Environmental Causes and Prevention Measures for Alzheimer’s Disease - 1st Edition - ISBN: 9780128111628

Environmental Causes and Prevention Measures for Alzheimer’s Disease

1st Edition

Authors: George Brewer
Paperback ISBN: 9780128111628
Imprint: Academic Press
Published Date: 5th October 2017
Page Count: 144
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Environmental Causes for Alzheimer’s Disease and Prevention Measures examines the increased incidence of the disease in developed countries and aims to educate neuroscientists, medical practitioners, and other educated individuals about new insights into environmental causation, primarily metals. This book looks into the web of evidence around the hypothesis of copper toxicity, and the additional role that a high fat diet plays in disease progression and cognition loss. The data and its implications are discussed, along with potential prevention measures, which will generate excitement and interest among neuroscientists, medical practitioners, and other biomedical researchers.

Key Features

  • Emphasizes and provide data on the history and epidemiology of Alzheimer’s disease, highlighting its epidemic proportions in developed countries but relative rarity in undeveloped countries
  • Discusses data on new environmental factors in developed countries
  • Provides prevention measures to potentially reduce Alzheimer’s rates through diet


Neuroscientists, medical professionals in neuroscience and neurology, toxicologists, biological scientists,  epidemiologists, postdoctoral fellows, and graduate students

Table of Contents

1. Introduction
2. A Little Background on Alzheimer’s Disease
3. Environmental Intoxicants
4. Candidate Environmental Factors: Diet and Other Lifestyle Factors (new chapter added in response to Reviewer Comments)
5. Candidate Environmental Factors: The Metals – Aluminum, Lead, Mercury, Zinc. Iron, and Copper (new chapter added in response to Reviewer Comments)
6. Copper as a Major Environmental Intoxicant (new chapter added in response to Reviewer Comments)
7. The Differences Between Inorganic Copper-2 and Organic Copper-1
8. Inorganic Copper as a Potential Major Cause for the Epidemic of Alzheimer’s Disease
9. Inorganic Copper-2 Ingestion
10. The Amyloid Cascade Hypothesis and Other Theories of Primary Alzheimer’s Disease Causation
11. Dietary Changes and Increased Copper Absorption in Developed Countries
12. Eliminating Ingestion of Inorganic Copper-2 and Diet Modification
13. Healthy Drinking Water and Nontoxic Multimineral/Multivitamin Pills


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© Academic Press 2018
Academic Press
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About the Author

George Brewer

Dr. Brewer has a bachelor’s degree in pharmacy and a medical degree. After completing his internship, fellowship and residency at the University of Chicago, he accepted a position at the NIH at Michigan’s Department of Human Genetics in 1963. He became an assistant professor of internal medicine and then full professor in five years, in the Departments of Human Genetics and Internal Medicine. He also was an adjunct professor of veterinary medicine at nearby Michigan State University from 1989 to 1995. During this time, Dr. Brewer developed zinc as a therapy for Wilson’s disease and received U.S. FDA approval. He is currently developing a drug for multiple therapeutic purposes. He has held memberships in more than 15 professional societies, serving as president of the regional chapter of the American Federation of Clinical Research, the American College of Nutrition and the International Society for Trace Elements Research in Humans. He has authored 342 publications and received numerous awards including the Distinguished Alumni Award from the University of Chicago, the Raulin Award from the International Society for Trace Element Research in Humans, and the Master Award from the American College of Nutrition. He is a Fellow in the American Association for the Advancement of Science.

Affiliations and Expertise

Morton S. and Henrietta K. Sellner Emeritus Professor of Human Genetics and Emeritus Professor of Internal Medicine, Retired, University of Michigan, Ann Arbor, MI, USA