Engineering Strategies for Regenerative Medicine

Engineering Strategies for Regenerative Medicine

1st Edition - November 13, 2019

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  • Editors: Tiago Fernandes, Maria Diogo, Joaquim Cabral
  • eBook ISBN: 9780128166703
  • Paperback ISBN: 9780128162217

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Engineering Strategies for Regenerative Medicine considers how engineering strategies can be applied to accelerate advances in regenerative medicine. The book provides relevant and up-to-date content on key topics, including the interdisciplinary integration of different aspects of stem cell biology and technology, diverse technologies, and their applications. By providing massive amounts of data on each individual, recent scientific advances are rapidly accelerating medicine. Cellular, molecular and genetic parameters from biological samples combined with clinical information can now provide valuable data to scientists, clinicians and ultimately patients, leading to the development of precision medicine. Equally noteworthy are the contributions of stem cell biology, bioengineering and tissue engineering that unravel the mechanisms of disease, regeneration and development.

Key Features

  • Considers how engineering strategies can accelerate novel advances in regenerative medicine
  • Takes an interdisciplinary approach, integrating different aspects of research, technology and application
  • Provides up-to-date coverage on this rapidly developing area of medicine
  • Presents insights from an experienced and cross-disciplinary group of researchers and practitioners with close links to industry


Research and development departments; graduate students, researchers in academia and industry; clinicians; industrial professionals; biomedical researchers; biomedical engineers

Table of Contents

  • Introduction
    1. Pluripotent Stem Cell Biology and Engineering
    2. Process Development and Manufacturing Approaches for Mesenchymal stem cell therapies
    3. Bio-inspired Materials and Tissue Engineering Approaches applied to the Regeneration of Musculoskeletal Tissues
    4. Bioengineering Strategies for Gene Delivery
    5. Advanced Microtechnologies for High-Throughput Screening
    6. Inductive Factors for generation of pluripotent stem cell-derived cardiomyocytes
    7. Pluripotent cells for the assessment of chemically-induced teratogenesis and developmental toxicology
    8. Conclusions and Closing Remarks

Product details

  • No. of pages: 284
  • Language: English
  • Copyright: © Academic Press 2019
  • Published: November 13, 2019
  • Imprint: Academic Press
  • eBook ISBN: 9780128166703
  • Paperback ISBN: 9780128162217

About the Editors

Tiago Fernandes

Dr Tiago G. Fernandes is currently a Post-doctoral research fellow at the Institute for Biotechnology and Bioengineering, Lisbon, Portugal. His research interests are focused on the development of artificial cellular niches for studying the mechanisms that affect human stem cell pluripotency, and the cellular and molecular events that regulate stem cell functions. During his doctoral studies he also worked at the Rensselaer Polytechnic Institute, NY, USA, in the development of microscale platforms for high-throughput studies of stem cell fate.

Affiliations and Expertise

Post-doctoral Research Fellow, Institute for Biotechnology and Bioengineering, Lisbon, Portugal

Maria Diogo

Dr Maria Margarida Diogo received her PhD degree in Biotechnology from Instituto Superior Técnico (IST) from January 2000 to April 2004. Her thesis was dedicated to the development of Bioprocesses for Production and Purification of Plasmid DNA for Gene Therapy and DNA vaccines. As a result of this work, a United States Patent was published in 2007. From April 2004 to March 2008 she received a post-doctoral fellowship to work in the field of Stem Cell Bioengineering and she is presently a Research Scientist at the Stem Cell Bioengineering Laboratory at Instituto Superior Técnico (IST).

Affiliations and Expertise

Stem Cell Bioengineering Laboratory, Instituto Superior Técnico (IST), Technical University of Lisbon, Portugal

Joaquim Cabral

Dr Joaquim M. S. Cabral is Professor of Biological Engineering, in the Department of Bioengineering at Instituto Superior Técnico (IST), Technical University of Lisbon, Portugal. He was the founder and current Head of Department of Bioengineering, and the Director of the Institute for Biotechnology and Bioengineering, a Research Laboratory Associated to the Ministry of Science, Technology and Higher Education in Portugal. His research aims at contributing to biochemical engineering science through novel developments in Bioprocess Engineering and Stem Cell Bioengineering.

Affiliations and Expertise

Instituto Superior Técnico (IST), Technical University of Lisbon, Portugal

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