Engineering Principles in Physiology

Engineering Principles in Physiology

Volume 2

1st Edition - January 1, 1973

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  • Editors: J. H. U. Brown, Donald S. Gann
  • eBook ISBN: 9781483216652

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Engineering Principles in Physiology, Volume II covers the mechanisms of cardiovascular systems, respiration, and cellular processes. This volume is organized into three parts encompassing 17 chapters. The first part describes the structure, function, mechanical properties, circulation, and control of the cardiovascular system. This part also examines the mechanism of cardiac pump, the atrial electrical activity, and the venous system. The second part explores the interrelationships between the morphology, physiology, and control mechanisms of respiration. This part also considers the mathematical theory of renal function. The third part looks into the cellular dynamics and intracellular processes. This book will prove useful to physiologists, biomedical engineers, and workers in the related fields.

Table of Contents

  • List of Contributors

    Contents of Volume I

    Part IV. The Cardiovascular System as an Integrative Mechanism

    13. Structure and Function of the Peripheral Circulation

    I. The General Organization of the Cardiovascular System

    II. Concepts of Rheology

    III. Architecture and Physical Properties of the Vascular System

    IV. Models of the Cardiovascular System


    14. The Circulation and Its Control I: Mechanical Properties of the Cardiovascular System

    I. Introduction

    II. The Cardiovascular Plant


    15. The Circulation and Its Control II: Neural and Humoral Control of the Heart and Vessels

    I. Multiple Controls of the Circulation

    II. Nervous Control of Heart Rate

    III. Control of Cardiac Contractility

    IV. Neural Control of the Vessels

    V. Humoral Control of the Vascular System

    VI. Integration of Neural and Humoral Control


    16. The Heart as a Pump

    I. Introduction

    II. Mechanics of Ventricular Contraction

    III. The Cardiac Pump and the Circulation


    17. Electrical Activity of the Heart

    I. Introduction

    II. Clinical Interpretation of ECG

    III. Atrial Electrical Activity

    IV. Polarization

    V. Pathology


    18. The Venous System

    I. Introduction

    II. The Parts of the System

    III. The System as a Whole

    IV. Transmural Pressures, the Respiratory Pump, and Venous Collapse


    Part V. Energy Flow in the System—Input and Output

    19. The Body as an Engine

    I. Introduction

    II. Information Content of the System

    III. The Muscle as an Engine

    IV. Total Energy of the System

    V. The Energy Cycle

    VI. Whole Body Metabolism

    VII. Biological Work


    20. The Respiratory Apparatus

    I. Introduction

    II. The Pulmonary Machine

    III. Coordination of Ventilation and Perfusion

    IV. Diffusion of Gases

    V. The Artificial Lung

    VI. The Energy Cost of Ventilation

    VII. Summary


    21. Regulation of Respiration: Interrelationships between Morphology, Physiology, and Control Mechanisms

    I. Introduction

    II. Metabolism as a Regulator

    III. Gas Exchange

    IV. Humoral Dependent Responses

    V. Mechanics

    VI. Pulmonary Function

    VII. Postural Dynamics

    VIII. Cardiovascular Interactions

    IX. Voluntary and Protective Mechanisms

    X. Control of Respiration


    22. Oxygen Transport

    I. Introduction

    II. Blood as a Transport Medium

    III. Transport of Oxygen in Blood

    IV. Transport of Oxygen in Tissue

    V. Control of Oxygen Transport



    23. The Mathematical Theory of Renal Function

    I. Introduction

    II. Functional Anatomy

    III. Some General Mathematical and Physical Principles

    IV. Overall Operation of the Kidney

    V. Overall Operation of the Nephron

    VI. Mathematical Theory of the Transport of Water and Solutes in the Proximal and Distal Convoluted Tubules

    VII. The Medullary Counterflow System

    VIII. Toward a Working Mathematical Model of the Kidney



    24. The Human Kidney

    I. Introduction

    II. General Considerations

    III. Renal Control Mechanisms

    IV. An Engineering Reconstruction


    Part VI. The Fine Structure of the System—Intracellular Processes

    25. Compartmental Approaches to Water and Electrolyte Distribution

    I. Introduction

    II. Compartment Theory

    III. Simulation of Total Body Fluid Systems

    IV. The Plasma-Red Cell Electrolyte Exchange System



    26. Cellular Dynamics

    I. Introduction

    II. Cell Structure

    III. Cell Metabolism

    IV. Metabolic Dynamics

    V. The Steady State


    27. Intracellular Processes

    I. Introduction

    II. Kinetics of the Intracellular Processes

    III. Input of Materials

    IV. Input-Output Balance

    V. Control of Intracellular Processe


    28. Diffusion as a Physiological Process

    I. Introduction

    II. Diffusive Mass Transfer in the Cornea

    III. Convective Flow in the Cornea and Sclera

    IV. Fluid Dynamics of Aqueous Humor Production and Outflow

    V. Heat Transfer in the Eye


    29. Ion Transport in Gastric Mucosa

    I. Introduction

    II. Anatomy and Physiology of the Stomach

    III. Active Transport of H+ and Cl-

    IV. Postulated Mechanisms to Explain HCl Production

    V. Evidence for Electrogenicity

    VI. Model to Explain Electrogenicity of H+ Mechanism


    Author Index

    Subject Index

Product details

  • No. of pages: 470
  • Language: English
  • Copyright: © Academic Press 1973
  • Published: January 1, 1973
  • Imprint: Academic Press
  • eBook ISBN: 9781483216652

About the Editors

J. H. U. Brown

Donald S. Gann

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