Energetics of Biological Macromolecules, Part C - 1st Edition - ISBN: 9780121822248, 9780080496788

Energetics of Biological Macromolecules, Part C, Volume 323

1st Edition

Editor-in-Chiefs: John Abelson Melvin Simon
Serial Volume Editors: Michael Johnson Gary Ackers
eBook ISBN: 9780080496788
Imprint: Academic Press
Published Date: 28th July 2000
Page Count: 584
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Description

Volume 323 of Methods in Enzymology is dedicated to the energetics of biological macromolecules. Understanding the molecular mechanisms underlying a biological process requires detailed knowledge of the structural relationships within the system and an equally detailed understanding of the energetic driving forces that control the structural interactions. This volume presents modern thermodynamic techniques currently being utilized to study the energetic driving forces in biological systems. It will be a useful reference source and textbook for scientists and students whose goal is to understand the energetic relationships between macromoleculer structures and biological functions. This volume supplements Volumes 259 and Volume 295 of Methods in Enzymology.

Key Features

@introbul:Key Features @bul:* Probing Stability of Helical Transmembrane Proteins

  • Energetics of Vinca Alkaloid Interactions with Tubulin
  • Deriving Complex Ligand Binding Formulas
  • Mathematical Modeling of Cooperative Interactions in Hemoglobin
  • Analysis of Interactions of Regulatory Protein TyrR with DNA
  • Parsing Free Energy of Drug-DNA Interactions
  • Use of Fluorescence as Thermodynamics Tool

Readership

Biochemists, biophysicists, molecular biologists, analytical chemists, and physiologists.


Details

No. of pages:
584
Language:
English
Copyright:
© Academic Press 2000
Published:
Imprint:
Academic Press
eBook ISBN:
9780080496788

Reviews

@from:Praise for the Series @qu:"The Methods in Enzymology series represents the gold-standard." @source:--NEUROSCIENCE @qu:"Incomparably useful." @source:--ANALYTICAL BIOCHEMISTRY @qu:"It is a true 'methods' series, including almost every detail from basic theory to sources of equipment and reagents, with timely documentation provided on each page." @source:--BIO/TECHNOLOGY @qu:"The series has been following the growing, changing and creation of new areas of science. It should be on the shelves of all libraries in the world as a whole collection." @source:--CHEMISTRY IN INDUSTRY @qu:"The appearance of another volume in that excellent series, Methods in Enzymology, is always a cause for appreciation for those who wish to successfully carry out a particular technique or prepare an enzyme or metabolic intermediate without the tiresome prospect of searching through unfamiliar literature and perhaps selecting an unproven method which is not easily reproduced." @source:--AMERICAN SOCIETY OF MICROBIOLOGY NEWS @qu:"If we had some way to find the work most often consulted in the laboratory, it could well be [the] multivolume series Methods in Enzymology...a great work." @source:--ENZYMOLOGIA @qu:"A series that has established itself as a definitive reference for biochemists." @source:--JOURNAL OF CHROMATOGRAPHY


About the Editor-in-Chiefs

John Abelson Editor-in-Chief

Affiliations and Expertise

California Institute of Technology, Division of Biology, Pasadena, U.S.A.

Melvin Simon Editor-in-Chief

Affiliations and Expertise

The Salk Institute, La Jolla, CA, USA

About the Serial Volume Editors

Michael Johnson Serial Volume Editor

Affiliations and Expertise

University of Virginia Health Sciences Center, Charlottesville, USA

Gary Ackers Serial Volume Editor

Affiliations and Expertise

Washington University School of Medicine, St. Louis, Mo, USA