An impressive four-volume work that provides an authoritative and comprehensive coverage of the complete field of respiratory medicine. It provides a vital interface between the pure and clinical science environments covering all aspects of respiratory medicine from the relevant molecular biology to the treatment of diseases that affect the respiratory system. It includes comprehensive coverage of lung cells, the structural components of the lung and key molecules that regulate lung function as well as all the major respiratory diseases. Students, researchers and professionals alike will find this an authoritative source of information on all aspects of respiratory medicine. Also available online via ScienceDirect (2006) – featuring extensive browsing, searching, and internal cross-referencing between articles in the work, plus dynamic linking to journal articles and abstract databases, making navigation flexible and easy. For more information, pricing options and availability visit

Key Features

* Includes diagrams of uniformly high quality and references to enable readers to access the wider literature * Highly structured through the use of chapter templates * Key four-color illustrations that will be invaluable teaching tools


Upper level undergraduates, graduate students, post docs and professionals in pulmonology, biochemistry, cell biology, immunology, physiology, anesthesiology, intensive care, and respiratory medicine

Table of Contents

TOPICS INCLUDE: Anatomy and development of the respiratory tract Anesthesia and surgery Biologic processes and associated cells and molecules Defence mechanisms Diagnostic evaluation Disorders of the control of breathing Disorders of the pleura Disorders of pulmonary circulation Environmental and occupational disease Exercise Infectious diseases Infiltrative and interstitial lung diseases Laboratory techniques for studying the lung in health and disease Lung growth Lung injury defence and repair Lung tissues Manifestations of respiratory disease Mechanics Morphogenesis Neonatal and pediatric lung Neoplasms Obstructive diseases Oxygen delivery Peripheral gas exchange Pulmonary circulation and fluid exchange Pulmonary gas exchange Respiratory failure Respiratory manifestations of extrapulmonary disease Respiratory physiology Respiratory pharmacology Sleep


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© 2006
Academic Press
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Electronic ISBN:

About the authors

Steven Shapiro

Steven J Shapiro MD is the Jack D. Myers Professor and Chair of the Department of Medicine at the University of Pittsburgh. Using a multidisciplinary approach, including cell and molecular biology, bioinformatics/functional genomics scientists, human geneticists, regenerative medicine biologists, and clinical trials, Dr Shapiro and his colleagues are attempting to understand the biological basis of COPD and develop a therapy to improve patient care. He is currently Editor in Chief of the American Journal of Respiratory Cell and Molecular Biology and serves on six additional editorial boards including the Journal of Clinical Investigation and Journal of Experimental Medicine. He is a recipient of the American Thoracic Society Research Achievement Award, and the Ochsner Award for tobacco-related research.

Geoffrey Laurent

Geoffrey J Laurent PhD Hon MRCP (U.K.) FRCPath (U.K.) is Professor and Director of the Centre for Respiratory Research at the Royal Free and University College Medical School, London, U.K., where he directs a team of internationally renowned scientists and physicians exploring the basic science of inflammation and tissue repair. He has published over 200 articles in international journals of biochemistry, cell biology and biomedical research and has edited several books. Professor Laurent is currently Editor in Chief of the International Journal of Biochemistry and Cell Biology, an Associate Editor of the American Journal of Respiratory Cell and Molecular Biology and a member of the editorial board of Thorax. He was recently awarded the European Respiratory Society Presidential Award for his contribution to lung research.