Encyclopedia of Biological Chemistry

1st Edition

Editors: William Lennarz M. Lane Paul Modrich Jack Dixon Ernesto Carafoli John Exton Don Cleveland
Hardcover ISBN: 9780124437104
Imprint: Academic Press
Published Date: 20th October 2004
Page Count: 3000


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Written for a broad, cross-disciplinary audience, the Encyclopedia of Biological Chemistry addresses the fundamental discipline of biological chemistry underlying virtually all of the life sciences. This compilation of more than 500 different entries encompasses all aspects of biochemistry, as well as the extensions of this subject into the related fields of molecular biology, cell biology, genetics and biophysics. This comprehensive encyclopedia covers all areas of biological chemistry written by more than 500 selected international experts. Articles are generously illustrated including more than 800 images in four-color. Each entry contains a clear, concise review of the topic along with illustrations, a glossary of technical terms and a section for additional reading.

Each entry further contains general background and term definitions as well as a comprehensive review of the current research in the field. Students, science journalists and scientists seeking a concise introduction to specific topics will appreciate the clear, tabular format of each entry.

Also available online via ScienceDirect – featuring extensive browsing, searching, and internal cross-referencing between articles in the work, plus dynamic linking to journal articles and abstract databases, making navigation flexible and easy. For more information, pricing options and availability visit www.info.sciencedirect.com.

Key Features

  • Four-volume set with topics arranged from A to Z for easy reference
  • Seven subject areas covering all areas of biological chemistry
  • Over 500 full-color articles of 4-9 pages each
  • Over 1300 illustrations throughout with 800 in 4-color and over 200 tables
  • Glossary of specialized terms and 'Further Reading' section provided for every article
  • Includes entries on the latest research techniques
  • Appropriate for students, researchers, and professionals


Upper level college students, postdocs, and professionals in biochemistry, biophysics, cell biology, molecular biology, neuroscience, pharmacology, and oncology, academic and industrial libraries, and pharmaceutical companies.

Table of Contents

ABC Transporters Abscisic Acid (ABA) Actin Assembly/Disassembly Actin Capping and Severing Proteins Actin-Related Proteins Adenosine Receptors Adenylyl Cyclases Adrenergic Receptors Affinity Chromatography Affinity Tags for Protein Purification Allosteric Regulation Alternative Splicing: Regulation of Fibroblast Growth Factor Receptor (FGFR) Alternative Splicing: Regulation of Sex Determination in Drosophila melanogaster Amine Oxidases Amino Acid Metabolism Aminopeptidases Amyloid Anaplerosis Angiotensin Receptors ara Operon ARF Family Proteins Aspartic Proteases ATP Synthesis in Plant Mitochondria: Substrates, Inhibitors, Uncouplers ATP Synthesis: Mitochondrial Cyanide-Resistant Terminal Oxidases Autophagy in Fungi and Mammals Bax and Bcl2 Cell Death Enhancers and Inhibitors B-Cell Antigen Receptor Bile Salts and Their Metabolism Biliary Cirrhosis, Primary Bioenergetics: General Definition of Principles Biotin Biotinylation of Proteins Bradykinin Receptors Branched-Chain ¨¢-Ketoacids Brassinosteroids B12-Containing Enzymes Cadherin Signaling Cadherin-Mediated Cell¨CCell Adhesion Calcitonin Gene-Related Peptide and Adrenomedullin Receptors Calcitonin Receptor Calcium-Binding Proteins, Cytosolic (Annexins, Gelsolins, C2-Domain Proteins) Calcium, Biological Fitness of Calcium Buffering Proteins: Calbindins Calcium Buffering Proteins: ER Luminal Proteins Calcium/Calmodulin-Dependent


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Academic Press
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About the Editor

William Lennarz

WILLIAM J. LENNARZ received his B.S. in Chemistry from Pennsylvania State University and a Ph.D. in Organic Chemistry from the University of Illinois. Subsequently he carried out postdoctoral work at Harvard with Konrad Bloch on fatty acid biosynthesis. In 1962 he was appointed Assistant Professor at Johns Hopkins in the Department of Physiological Chemistry. After promotion to Associate Professor in 1967, and full Professor in 1971, he remained at Hopkins until 1983. At that time, he was appointed Robert A. Welch Professor and Chair of the Department of Biochemistry and Molecular Biology at the University of Texas Cancer Center, M.D. Anderson Hospital. In 1989 he became a Leading Professor and Chair of the Department of Biochemistry and Cell Biology at SUNY at Stony Brook. In 1990 he founded and became Director of the Institute for Cell and Developmental Biology at Stony Brook.

Dr. Lennarz has served on many national and international committees. He has served as President of the Biochemistry Chairman's Organization, President of the American Society for Biochemistry and Molecular Biology and President of the Society for Glycobiology. He was a member of the Executive Committee of the International Union of Biochemistry and Molecular Biology for almost a decade.

He has presented special lectures at the University of Notre Dame, the NIH, the University of West Virginia, Johns Hopkins University, Florida State University, the University of California at San Diego, the University of Arkansas, Indiana University and the Medical College of Virginia.

He is a member of the National Academy of Sciences. The focus of his early work was on lipids and bacterial cell surfaces. More recent efforts have been in the structure, biosynthesis and function of cell surface glycoproteins. The biosynthesis studies initially were carried out in liver and oviduct, but these efforts now are focused in yeast. The functional studies have concentrated on the role o

Affiliations and Expertise

State University of New York, Department of Biochemistry and Cell Biology, Stony Brook, U.S.A.

M. Lane

M. Daniel Lane, Ph.D. is Distinguished Service Professor of Biological Chemistry at the Johns Hopkins Medical School. He received B.S. and M.S. degrees from Iowa State University, a Ph.D. degree from the University of Illinois and an honorary Doctor of Humane Letters degree, from Iowa State University. He did a Senior Postdoctoral Fellowship with Professor Feodor Lynen at the Max-Planck Institute Für Zellchemie in Munich. Following faculty positions at Virginia Tech and New York University School of Medicine, he joined (in 1970) the faculty at the Johns Hopkins Medical School where he served as DeLamar Professor and Director of the Department of Biological Chemistry from 1978 to 1997. He was elected to membership in the National Academy of Sciences and the American Academy of Arts and Sciences (1987) and as a Fellow of the American Society of Nutritional Sciences (1996). He received the Mead Johnson Award from the American Society for Nutritional Sciences and the William C. Rose Award from the American Society for Biochemistry and Molecular Biology and served as President of the American Society of Biochemistry and Molecular Biology. He served on numerous editorial boards including the Journal of Biological Chemistry and the Annual Reviews of Biochemistry. With William Lennarz he co-edited the first edition (2004) of the Encyclopedia of Biological Chemistry. Currently he is Associate Editor for Biochemical and Biophysical Research Communications. His early work focused on enzymatic CO2 fixation reactions, notably the mechanisms by which the B-vitamin, biotin, functions in carboxylases. His research on acetyl-CoA carboxylase, key regulatory enzyme of fatty acid synthesis, led him to his present interests in the basic mechanisms of lipogenesis, adipogenesis and the hypothalamic control of energy balance.

Affiliations and Expertise

Johns Hopkins University, Baltimore, Maryland, USA

Paul Modrich

Affiliations and Expertise

Department of Biochemistry, Duke University Medical Center, Durham, North Carolina, USA

Jack Dixon

Ernesto Carafoli

John Exton

Don Cleveland


"There is excellent use of headings and subheadings to allow for easy scanability for relevant information. The binding is sturdy and the overall appearance of the encyclopedia is exceptional...highly recommended for academic and special libraries. The cross-disciplinary nature of this resource makes it a valuable item. It is current, comprehensive, and thoroughly researched, and will be a valuable resource for anyone looking for information in biological chemistry and its related fields." --E-STREAMS, 2005