Emerging Technologies for Heart Diseases - 1st Edition - ISBN: 9780128137062

Emerging Technologies for Heart Diseases

1st Edition

Volume 1: Heart Failure and Valvular Disease

Editors: Udi Nussinovitch
Hardcover ISBN: 9780128137062
Imprint: Academic Press
Published Date: 1st March 2020
Page Count: 352
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Description

Emerging Technologies for Heart Diseases: Volume 1: Heart Failure and Valvular Disease covers current and novel therapeutic options for cardiac patients. The first volume is dedicated to heart failure and valvular disorders, with the second covering myocardial ischemia and arrhythmias. Each clinical topic is addressed in several chapters that are divided according to the therapeutic approach (mechanical or electrical device-based, or cell and gene-based). Each chapter focuses on clinically available solutions, new therapies currently under evaluation, promising preclinical technologies, and emerging concepts and innovations that have not yet been tested. In addition, the book discusses future challenges and opportunities for clinical implementation.

Finally, lessons learned from abandoned experimental practices are also covered, giving the readers the widest possible perspective of current therapeutic dilemmas. Overall, this textbook was designed for physicians who want to stay up-to-date on current and future therapies, for biomedical companies, and for those who wish to broaden their knowledge of new cardiovascular therapeutic options.

Key Features

  • Provides a comprehensive review of the latest therapeutic developments for heart failure, valvular heart disease and clinical implications
  • Delivers a review of emerging medical technologies and presents insights into their therapeutic promise
  • Presents chapters that are arranged according to disease pathogeneses and relevance
  • Includes coverage of mechanical, electrophysiological and biological approaches in the management of patients with heart failure

Readership

Basic scientists who develop biological approaches for the treatment of heart conditions. Medical professionals who wish to enhance their knowledge of current and emerging medical

Table of Contents

Volume 1:

SECTION 1: Treatment of heart failure – device-based therapies
1. Artificial mechanical hearts and ventricular assist devices
2. Cardiac resynchronization therapy
3. Left atrial decompression devices
4. Treatment of diastolic heart failure
5. Treatment of volume overload

SECTION 2: Treatment of systolic heart failure - cell and gene based therapies, and tissue engineering approach
6. Xenotransplantation
7. Marrow-derived stromal cells
8. Cardiac derived stem cells and cardiac progenitor cells (CPC)
9. Human embryonic stem cells
10. Induced pluripotent stem cells (iPSCs)
11. Transdifferentiation
12. In-vitro cardiac tissue engineering
13. Decellularization techniques
14. Gene and protein therapy for myocardial regeneration

SECTION 3: Treatment of systolic heart failure - modulation of the extracellular matrix and cardiac structure
15. Biopolymers
16. Cardiac reconstruction

SECTION 4: Treatment of systolic heart failure - novel pharmacological treatments
17. Novel pharmacotherapy for treatment of heart failure

SECTION 5: Treatment of valvular diseases
18. Cell, gene, and tissue engineering approach towards regeneration of heart valves
19. Transaortic valve implantation (TAVI)
20. Mitral valve modulation and repair
21. Percutaneous mitral valve replacement

Details

No. of pages:
352
Language:
English
Copyright:
© Academic Press 2020
Published:
Imprint:
Academic Press
Hardcover ISBN:
9780128137062

About the Editor

Udi Nussinovitch

Udi Nussinovitch, MD, PhD graduated in 2007 from the Sackler Faculty of Medicine, Tel Aviv University, training at The Sheba Medical Center, The Rambam Healthcare Center and the Israeli Naval Medical Institute (INMI) while concurrently graduating with a PhD in cardiac electrophysiology from the Technion Institute of Technology, Israel. Dr Nussinovitch has dedicated his research to investigating novel therapeutic approaches for tachy- and bradyarrhythmias and the modulation of the cardiac electrophysiologic substrate for therapeutic purposes. He has published articles in leading scientific journals and has authored articles focusing on the cardiovascular system. He has also published several chapters in scientific textbooks and was the editor of a clinical cardiac textbook entitled The Heart in Rheumatic, Autoimmune and Inflammatory Diseases: Pathophysiology, Clinical Aspects and Therapeutic Approaches, 1st edition; 2017, Elsevier Publishing Group. Recently, Dr Nussinovitch co-founded several biotech companies. He also authored several articles for “Medgadget”, a highly read medical internet blog focusing on emerging medical technologies. Dr Nussinovitch has been the recipient of several research awards and has served as a reviewer for leading journals within the scope of his expertise. Dr Nussinovitch carries out his clinical work at the Rambam Healthcare Center, a tertiary medical facility and leading referral center in northern Israel.

Affiliations and Expertise

Rambam Medical Center and Technion Institute of Technology, Israel

Ratings and Reviews