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Emerging Nanotechnologies in Immunology - 1st Edition - ISBN: 9780323400169, 9780323401135

Emerging Nanotechnologies in Immunology

1st Edition

The Design, Applications and Toxicology of Nanopharmaceuticals and Nanovaccines

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Editors: Ranjita Shegokar Eliana Souto
Hardcover ISBN: 9780323400169
eBook ISBN: 9780323401135
Imprint: Elsevier
Published Date: 19th May 2018
Page Count: 290
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Table of Contents

1. Nanopharmaceutics in immunology: what's new in research?
Ranjita Shegokar, Ana Rita Fernandes and Eliana Souto
2. Skin delivery of antimicrobial peptides
Monika Schaefer-Korting and Jens Rolff
3. Skin penetration of nanoparticles
Shohreh Nafisi and Howard I. Maibach
4. Regulatory and risk assessment perspective for Core-Multishell Nanocarriers: A novel excipient on its way towards marketing authorization
Sam D. More, Margret More, Florian Paulus, Emanuel Fleige amd Marcin Libera
5. Anti-inflammatory drugs: Pharmaceutical Nanotechnology approach
Andjelka B. Kovačevic, Sergio M.C.Silva and Slavomira Doktorovova
6. New strategies for the treatment of auto-immune diseases using nanotechnologies
Amelia M. Silva, Joao R. Siopa, Carlos Martins-Gomes, Maria C. Teixeira, Dario J. Santos, Maria dos Anjos Pires and Tatiana Andreani
7. Nanopharmaceutics Applications in Inhaler Systems
Aysu Yurdasiper, Mesut Arici and Mine Ozyazici
8. Immunomodulatory Effects of Curcumin in infectious and non-infectious diseases
Ranjita Shegokar
9. Advances in Antibiotic Nanotherapy: Overcoming Antimicrobial Resistance
Teixeira, M.C., Sanchez-Lopez, E., Espina, M., Calpena, A.C., Silva, A.M., Veiga, F.J., Garcia, M. L., Souto, E.B.


Emerging Nanotechnologies in Immunology aims to deliver a systematic and comprehensive review of data concerning the nature of interaction and nano-related risks between the nanophamaceuticals currently in the pipeline of S&T development for skin, ocular, and nasal drug delivery, including absorption, toxicity, and the ability to distribute after systemic exposure.

The scientific development of manufactured nanomaterials for drug delivery is increasing rapidly. One of the most prominent applications is topical drug delivery, where cutaneous, ocular, and nasal exposure becomes even more relevant. These targets are the first barrier that nanoparticles encounter when in contact with the human body.

The contributors addresses a representative set of the broad spectrum of nanopharmaceuticals currently being used, including cationic lipid nanoparticles, polymeric PLGA, PLA nanoparticles, biomacromolecules-based nanoparticles, and other scaffolds tissue engineered skin substitutes. Regulation and risk is also covered, since the safety of these nanophamaceuticals still represents a barrier to their wide innovative use.

Key Features

  • Provides the reader with a thorough knowledge of the safety aspects of nanopharmaceuticals which are currently under research
  •  Focuses on the characterization and quantification of the nanopharmaceuticals
  • Allows readers to understand the correlation between the nature of the materials and their potential nanotoxicological effects.
  • Includes an overview of regulatory aspects related to the R&D of nanopharmaceuticals.


Academics, researchers and scientists, as well as post-graduates, developing their research in the area of Topical Drug Delivery; Policy makers and pharmaceutical companies and learned societies, associations and research groups working in topical nanopharmaceuticals


No. of pages:
© Elsevier 2018
19th May 2018
Hardcover ISBN:
eBook ISBN:

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About the Editors

Ranjita Shegokar

Dr. Ranjita Shegokar holds a PhD degree in Pharmaceutical Technology from the SNDT University, India, and has been postdoctoral researcher in the Department of Pharmaceutics, Biopharmaceutics and NutriCosmetics at Free University of Berlin, Germany. Since last 8 years she is working in the pharmaceutical industry in various technical/R&D roles. Currently, she serves as Director of Pharma Business Unit at Capnomed GmbH, Germany. She has authored many research articles, book chapters, and presented several research papers in conferences. She has filed multiple patent application in area of drug delivery and drug targeting. She received several national and international awards for her research. Her areas of interest include polymeric nanoparticles, nanocrystals, lipid nanoparticles (SLNs/NLCs), nanoemulsions and role of excipients in delivery systems.

Affiliations and Expertise

Director, Pharma Business Unit, Capnomed GmbH, Germany

Eliana Souto

Prof. Eliana B. Souto is affiliated with the Department of Pharmaceutical Technology of the Faculty of Pharmacy, University of Coimbra, Portugal. She is graduated in Pharmaceutical Sciences from the same University (2000). She holds a master’s degree in Pharmaceutical Technology and Pharmacotechnique from the Faculty of Pharmacy, University of Porto, Portugal (2002) and a PhD in Pharmaceutical Technology, Biopharmaceutics, and Biotechnology from the Institut fuer Pharmazie der Freie Universitaet Berlin, Germany (2005). Since August 2012, she has held the habilitation degree (Dr. Habil.) from the University Fernando Pessoa, Portugal. Her research lines focus on the design, development, and characterization of new drug delivery systems. Other research interests include the controlled delivery of drugs across biological barriers, with especial emphasis for ocular and skin administration.

Affiliations and Expertise

Department of Pharmaceutical Technology of the Faculty of Pharmacy, University of Coimbra, Portugal.