Emerging Nanotechnologies in Immunology

Emerging Nanotechnologies in Immunology

The Design, Applications and Toxicology of Nanopharmaceuticals and Nanovaccines

1st Edition - May 17, 2018

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  • Editors: Ranjita Shegokar, Eliana Souto
  • Hardcover ISBN: 9780323400169
  • eBook ISBN: 9780323401135

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Emerging Nanotechnologies in Immunology aims to deliver a systematic and comprehensive review of data concerning the nature of interaction and nano-related risks between the nanophamaceuticals currently in the pipeline of S&T development for skin, ocular, and nasal drug delivery, including absorption, toxicity, and the ability to distribute after systemic exposure.The scientific development of manufactured nanomaterials for drug delivery is increasing rapidly. One of the most prominent applications is topical drug delivery, where cutaneous, ocular, and nasal exposure becomes even more relevant. These targets are the first barrier that nanoparticles encounter when in contact with the human body.The contributors addresses a representative set of the broad spectrum of nanopharmaceuticals currently being used, including cationic lipid nanoparticles, polymeric PLGA, PLA nanoparticles, biomacromolecules-based nanoparticles, and other scaffolds tissue engineered skin substitutes. Regulation and risk is also covered, since the safety of these nanophamaceuticals still represents a barrier to their wide innovative use.

Key Features

  • Provides the reader with a thorough knowledge of the safety aspects of nanopharmaceuticals which are currently under research
  • Focuses on the characterization and quantification of the nanopharmaceuticals
  • Allows readers to understand the correlation between the nature of the materials and their potential nanotoxicological effects
  • Includes an overview of regulatory aspects related to the R&D of nanopharmaceuticals


Academics, researchers and scientists, as well as post-graduates, developing their research in the area of Topical Drug Delivery; Policy makers and pharmaceutical companies and learned societies, associations and research groups working in topical nanopharmaceuticals

Table of Contents

  • 1. Nanopharmaceutics in immunology: what's new in research?
    Ranjita Shegokar, Ana Rita Fernandes and Eliana Souto
    2. Skin delivery of antimicrobial peptides
    Monika Schaefer-Korting and Jens Rolff
    3. Skin penetration of nanoparticles
    Shohreh Nafisi and Howard I. Maibach
    4. Regulatory and risk assessment perspective for Core-Multishell Nanocarriers: A novel excipient on its way towards marketing authorization
    Sam D. More, Margret More, Florian Paulus, Emanuel Fleige amd Marcin Libera
    5. Anti-inflammatory drugs: Pharmaceutical Nanotechnology approach
    Andjelka B. Kovačevic, Sergio M.C.Silva and Slavomira Doktorovova
    6. New strategies for the treatment of auto-immune diseases using nanotechnologies
    Amelia M. Silva, Joao R. Siopa, Carlos Martins-Gomes, Maria C. Teixeira, Dario J. Santos, Maria dos Anjos Pires and Tatiana Andreani
    7. Nanopharmaceutics Applications in Inhaler Systems
    Aysu Yurdasiper, Mesut Arici and Mine Ozyazici
    8. Immunomodulatory Effects of Curcumin in infectious and non-infectious diseases
    Ranjita Shegokar
    9. Advances in Antibiotic Nanotherapy: Overcoming Antimicrobial Resistance
    Teixeira, M.C., Sanchez-Lopez, E., Espina, M., Calpena, A.C., Silva, A.M., Veiga, F.J., Garcia, M. L., Souto, E.B.

Product details

  • No. of pages: 290
  • Language: English
  • Copyright: © Elsevier 2018
  • Published: May 17, 2018
  • Imprint: Elsevier
  • Hardcover ISBN: 9780323400169
  • eBook ISBN: 9780323401135

About the Editors

Ranjita Shegokar

Ranjita Shegokar holds a Ph.D. degree in Pharmaceutical Technology from the SNDT University, India, and has been a postdoctoral researcher in the Department of Pharmaceutics, Biopharmaceutics and NutriCosmetics at the Free University of Berlin, Germany. For the last many years, she has been working with various multinational pharmaceutical companies in technical/R&D leadership roles. Currently, she serves as Chief Scientific Officer (CSO) at Capnopharm GmbH, Germany. She has authored several research articles, book chapters, and presented her research in many national/international conferences. She has filed multiple patent applications in the area of drug delivery and targeting. Besides that, she has edited many trending books in the area of pharmaceutical nanotechnology and drug delivery aspects. For her research, she has received many prestigious national and international awards among them include recently received prestigious German Innovation Award 2022. Her areas of interest include polymeric nanoparticles, nanocrystals, lipid nanoparticles (SLNs/NLCs), nanoemulsions, cancer drug targeting and the role of excipients in delivery systems. (www.ranjitas.com)

Affiliations and Expertise

Postdoctoral Researcher, Department of Pharmaceutics, Biopharmaceutics and NutriCosmetics, Free University of Berlin, Germany

Eliana Souto

Eliana B. Souto is Habil. Professor from the Department of Pharmaceutical Technology of the Faculty of Pharmacy of University of Porto. Prof. Souto graduated in Pharmaceutical Sciences from University of Coimbra (2000), is holder of a master’s in science degree in Pharmaceutical Technology from University of Porto (2002), and PhD in Pharmaceutical Nanotechnology and Biopharmaceutics from the Institut fuer Pharmazie der Freie Universitaet Berlin, Germany (2005). Her research lines include the design, development, and characterization of new drug delivery systems to overcome biological barriers. Prof. Souto serves as Associate Editor, member of the Editorial Board, and Reviewer of several international scientific journals and has published more than 500 works (original and review papers, books and book chapters) in the field of nanosciences and nanomedicine. Prof. Souto also acts as independent expert for several national, European and international funding agencies, and as consultant for pharmaceutical industry.

Affiliations and Expertise

Professor, Department of Pharmaceutical Technology of the Faculty of Pharmacy, University of Porto, Portugal

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