Emerging Nanotechnologies in Dentistry

Emerging Nanotechnologies in Dentistry

Processes, Materials and Applications

2nd Edition - October 30, 2017

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  • Editors: Karthikeyan Subramani, Waqar Ahmed
  • Hardcover ISBN: 9780128122914
  • eBook ISBN: 9780128122921

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Description

Emerging Nanotechnologies in Dentistry, Second Edition, brings together an international team of experts from the fields of materials science, nanotechnology and dentistry to explain these new materials and their applications for the restoration, fixation, replacement or regeneration of hard and soft tissues in and about the oral cavity and craniofacial region. New nanomaterials are leading to a range of emerging dental treatments that utilize more biomimetic materials that more closely duplicate natural tooth structure (or bone, in the case of implants). Each chapter has been comprehensively revised from the first edition, and new chapters cover important advances in graphene based materials for dentistry, liposome based nanocarriers and the neurotoxicity of nanomaterials used in dentistry.

Key Features

  • Offers a comprehensive professional reference for the subject covering materials fabrication and use of materials for all major diagnostic and therapeutic dental applications: repair, restoration, regeneration, implants and prevention
  • Focuses in depth on the materials manufacturing processes involved, with emphasis on pre-clinical and clinical applications, use and biocompatibility
  • Examines the use of novel nanomaterials including graphene in dentistry, exploring how these may best be used

Readership

Academics and biomedical engineers working in the areas of nanomedicine, nanomaterials, dentistry and oral health

Table of Contents

  • Cover image
  • Title page
  • Table of Contents
  • Copyright
  • Dedication
  • List of Contributors
  • Foreword
  • Acknowledgments
  • Chapter 1. Nanotechnology and its applications in dentistry—An introduction
  • Abstract
  • 1.1 Introduction
  • 1.2 Nanotechnology Approaches
  • 1.3 Nanotechnology to Nanomanufacturing
  • 1.4 Nanodentistry
  • 1.5 Future Directions and Conclusions
  • References
  • Chapter 2. Nanoparticles for dental materials: Synthesis, analysis, and applications
  • Abstract
  • 2.1 Introduction: Why Use Nanoparticles?
  • 2.2 Synthesis of Nanoparticles
  • 2.3 Examples of Dental Materials Using Nanoparticles
  • 2.4 Selected Properties of Dental Materials Containing Nanoparticles
  • 2.5 Clinical Experience With Dental Materials Containing Nanoparticles
  • 2.6 Conclusions
  • References
  • Chapter 3. Antimicrobial nanoparticles in restorative composites
  • Abstract
  • 3.1 Introduction
  • 3.2 Antibacterial Restorative Composites
  • 3.3 Antimicrobial Macromolecules
  • 3.4 Nanoparticles
  • 3.5 Conclusions
  • References
  • Chapter 4. Nanotechnology in operative dentistry: A perspective approach of history, mechanical behavior, and clinical application
  • Abstract
  • 4.1 Introduction
  • 4.2 Historical Review: Nanotechnology Applications in Operative Dentistry
  • 4.3 Biomimetics
  • 4.4 Nanotechnology in CAD/CAM
  • 4.5 Fillers in Composite Resins
  • 4.6 SEM and EDS Evaluations
  • 4.7 Filler Weight Content (wt%)
  • 4.8 Water Sorption
  • 4.9 Mechanical Behavior
  • 4.10 Clinical Application
  • 4.11 Conclusions
  • Acknowledgments
  • References
  • Chapter 5. Impact of nanotechnology on dental implants
  • Abstract
  • 5.1 Introduction
  • 5.2 Nanoscale Surface Modifications
  • 5.3 Interactions of Surface Dental Implants With Blood
  • 5.4 Interactions Between Surfaces and MSCs
  • 5.5 Tissue Integration
  • 5.6 Conclusion
  • Acknowledgments
  • References
  • Chapter 6. Titanium surface modification techniques for dental implants—From microscale to nanoscale
  • Abstract
  • 6.1 Introduction
  • 6.2 Titanium Surface Modification Methods
  • 6.3 Recent Techniques
  • 6.4 Limitations & Conclusion
  • Acknowledgments
  • References
  • Chapter 7. Titanium nanotubes as carriers of osteogenic growth factors and antibacterial drugs for applications in dental implantology
  • Abstract
  • 7.1 Introduction
  • 7.2 Titanium Nanotubes
  • 7.3 TiO2 Nanotubes for Implant Fabrication
  • 7.4 Functionalization of TiO2 Nanotubes with Growth Factors and Antibacterial/Antiinflammatory Drugs
  • 7.5 Recent Advancements
  • 7.6 Conclusions
  • References
  • Chapter 8. Cellular responses to nanoscale surface modifications of titanium implants for dentistry and bone tissue engineering applications
  • Abstract
  • 8.1 Introduction
  • 8.2 Nanotopography Generated from Surface Modification of Ti Implants
  • 8.3 Nanotopography and Protein Absorption
  • 8.4 Nanotopography Alters Osteoblast Responses
  • 8.5 Nanotopography and Stem Cell Responses
  • 8.6 Conclusions
  • References
  • Chapter 9. Corrosion resistance of Ti–6Al–4V with nanostructured TiO2 coatings
  • Abstract
  • 9.1 Introduction
  • 9.2 Nanostructured TiO2 Deposited on Ti–6Al–4V
  • 9.3 Characterization Techniques
  • 9.4 Corrosion Test With Electrochemical Techniques
  • 9.5 Conclusion
  • References
  • Chapter 10. Multiwalled Carbon nanotubes/hydroxyapatite nanoparticles incorporated GTR membranes
  • Abstract
  • 10.1 Introduction
  • 10.2 Periodontal Defects and GTR
  • 10.3 Use of Electrospinning for Preparation of Nanocomposites
  • 10.4 GTR Membranes Based on Electrospun CNT/HA Nanoparticles Incorporated Composite Nanofibers
  • 10.5 Conclusions
  • References
  • Chapter 11. Nanoapatitic composite scaffolds for stem cell delivery and bone tissue engineering
  • Abstract
  • 11.1 Introduction
  • 11.2 Development of Nanoapatitic and Macroporous Scaffolds
  • 11.3 Cell Infiltration into Scaffold
  • 11.4 Biomimetic Nanoapatite–Collagen Fiber Scaffold
  • 11.5 Fast Fracture of Nanoapatite Scaffold
  • 11.6 Fatigue of Nanoapatite Scaffold
  • 11.7 Nanoapatite Scaffold–Human Umbilical Cord Stem Cell Interactions
  • 11.8 Seeding Bone Marrow Stem Cells on Nanoapatite Scaffolds
  • 11.9 Conclusions
  • Acknowledgments
  • References
  • Chapter 12. Self-assembly of proteins and peptides and their applications in bionanotechnology and dentistry
  • Abstract
  • 12.1 Introduction
  • 12.2 Mechanism of Molecular Self-Assembly
  • 12.3 Classification of Self-Assembly
  • 12.4 Self-Assembly of Proteins and Peptides
  • 12.5 Bionanotechnology Applications
  • 12.6 Peptide Nanofibers, Nanotubes, and Nanowires
  • 12.7 Three-Dimensional Peptide Matrix Scaffolds
  • 12.8 Advantages and Limitations of Self-Assembling Peptide Matrix Scaffolds
  • 12.9 Self-Assembly in Regenerative Biology and Dentistry
  • 12.10 Conclusions
  • References
  • Chapter 13. Surface engineering of dental tools with diamond for enhanced life and performance
  • Abstract
  • 13.1 Tooth Materials
  • 13.2 Dental Burs
  • 13.3 Chemical Vapor Deposition of Diamond Films Onto Dental Burs
  • 13.4 Bur Performance Investigations
  • 13.5 Conclusions
  • References
  • Further Reading
  • Chapter 14. Nanomechanical characterization of mineralized tissues in the oral cavity
  • Abstract
  • 14.1 Introduction
  • 14.2 Basic Data Analysis Protocol for Nanoindentation
  • 14.3 Nanoindentation of Oral Mineralized Tissues
  • 14.4 Summary
  • References
  • Further Reading
  • Chapter 15. Nanoindentation techniques for the determination of mechanical properties of materials in dentistry
  • Abstract
  • 15.1 Introduction
  • 15.2 Basic Information From the Load–Displacement Curves
  • 15.3 Characterization of Inelastic Properties
  • 15.4 Determination of Properties in Nonhomogeneous Bodies
  • 15.5 Characterization of Time-Dependent Load Response
  • 15.6 Resistance Against Crack Propagation
  • 15.7 Scratch Tests for the Evaluation of Friction and Wear Resistance
  • 15.8 Devices for Nanoindentation
  • Acknowledgments
  • References
  • Chapter 16. Nanocharacterization techniques for dental implant development
  • Abstract
  • 16.1 Measurement of the Topology of Nanostructures
  • 16.2 Measurement of Nanostructure Internal Geometries
  • 16.3 Measurement of Composition of Nanostructures
  • 16.4 Measurement of the Mechanical Properties of Nanostructures
  • 16.5 Conclusions
  • References
  • Chapter 17. Nanoparticulate drug-delivery systems for oral cancer treatment
  • Abstract
  • 17.1 Introduction
  • 17.2 Cancer-Treatment Techniques
  • 17.3 Mechanism of Action of Chemotherapeutic Agents
  • 17.4 Oral Cancer
  • 17.5 TNM Classification of Tumors
  • 17.6 Management of Oral Cancer
  • 17.7 Nanoparticulate-Based Drug Delivery in Cancer Treatment
  • 17.8 Limitations of Nanoparticles and Conclusion
  • References
  • Chapter 18. Carbon nanotubes: Applications in cancer therapy and drug delivery research
  • Abstract
  • 18.1 Introduction
  • 18.2 Cellular Uptake of CNTs
  • 18.3 CNTs as Carriers for Small and Large Drug Molecules
  • 18.4 Carbon Nanotubes for Oral Cancer Therapy
  • 18.5 Conclusion
  • References
  • Chapter 19. Nanodiagnostics in microbiology and dentistry
  • Abstract
  • 19.1 Introduction
  • 19.2 Nanomaterials
  • 19.3 Biomedical Applications of Nanotechnology and Its Limitations
  • 19.4 Nanotechnology Applications in Drug-Delivery Systems, Nanodiagnostics, and Various Other Fields
  • 19.5 Contribution of Microbiology to Nanotechnology
  • 19.6 AFM Imaging of Microorganisms
  • 19.7 Nanoplasmonic Sensors Detecting Live Viruses
  • 19.8 Nanodentistry
  • 19.9 Conclusions
  • References
  • Chapter 20. Neurotoxicity of nanomaterials
  • Abstract
  • 20.1 Introduction
  • 20.2 Possible Dental Nanomaterials
  • 20.3 Neurotoxicity of Dental Nanomaterials
  • 20.4 Future Research Prospects
  • 20.5 Conclusion
  • Acknowledgments
  • References
  • Index

Product details

  • No. of pages: 496
  • Language: English
  • Copyright: © Elsevier 2017
  • Published: October 30, 2017
  • Imprint: Elsevier
  • Hardcover ISBN: 9780128122914
  • eBook ISBN: 9780128122921

About the Editors

Karthikeyan Subramani

Assistant Professor of Dental Medicine at Roseman University of Health Sciences, USA. He was the recipient of the prestigious 2006 Andre Schroeder Research Prize from Straumann (Switzerland) for his innovative research findings during his Biomedical Nanotechnology degree program in the United Kingdom. Dr. Subramani was involved in the International Team for Implantology (ITI) funded research projects in Switzerland, the Netherlands and in the USA. He has authored numerous peer-reviewed research papers and review manuscripts and has authored numerous book chapters. He is also the editor of the Elsevier book Nanomaterials in Clinical Dentistry together with Waqar Ahmed.

Affiliations and Expertise

College of Dental Medicine, Roseman University of Health Sciences, Henderson, NV, USA

Waqar Ahmed

Professor of Nanotechnology at the University of Lincoln, UK. His research interests include the synthesis of nanomaterials and nanoparticles and their applications in medicine, dentistry and energy applications

Affiliations and Expertise

School of Mathematics and Physics, University of Lincoln, Lincoln, UK

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