Drugs in Psychiatric Practice

Drugs in Psychiatric Practice

1st Edition - February 2, 1983

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  • Author: Unknown Author
  • eBook ISBN: 9781483191935

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Description

Drugs in Psychiatric Practice present a comprehensive examination of the drug treatment in psychiatry. It discusses certain ways in which drugs behaved. It addresses the advances in pharmacology and the basis of prescription. Some of the topics covered in the book are the classification of psychotropic drugs; basic principles of pharmacokinetics and drug metabolism; anti-schizophrenic drugs; evaluation of psychotropic drugs; unconventional chemotherapy; anti-parkinsonian and anti-dyskinetic drugs; introduction of amitriptyline; and tricyclic antidepressants. The role of tricyclic drugs in the treatment of enuresis and the drug treatment of organic brain syndrome are fully covered. An in-depth account of the monoamine oxidase inhibitors and amine precursors are provided. The tolerance and pharmacological dependence on alcohol are completely presented. A chapter is devoted to the factors involve in ethanol metabolism. Another section focuses on the unwanted effects of psychotropic drugs. The book can provide useful information to doctors, pharmacists, psychologists, students, and researchers.

Table of Contents


  • Introduction

    1 Classification of Psychotropic Drugs

    What is a Psychotropic Drug?

    Types of Classification

    Classification of Drugs Used in This Book

    2 Pharmacokinetics and Drug Metabolism—Basic Principles

    Definitions and Basic Principles in Pharmacokinetics

    Absorption

    Protein Binding and Distribution

    Metabolism

    Excretion

    Pharmacokinetics and Pharmacological Effect

    Conclusions

    3 Evaluation of Psychotropic Drugs

    Animal Studies

    Experimental Studies in Volunteers

    Experimental Studies in Patients

    Early Clinical Trials

    Controlled Clinical Trials

    Marketing

    Early and Late Clinical Evaluation

    4 Antischizophrenic Drugs

    Introduction

    Nomenclature

    Unconventional Chemotherapy

    Pharmacology

    Non-DA-Related Pharmacology

    Pharmacokinetics

    Clinical Efficacy

    Unwanted Effects

    5 Antiparkinsonian and Antidyskinetic Drugs

    Introduction

    Pathophysiology of Neuroleptic-Induced Movement Disorders

    Drug Treatment of Neuroleptic-Induced Movement Disorders

    6 Antianxiety Drugs

    Generalized Central Anxiolytics (Sedative Drugs)

    Specific Central Anxiolytics (Ataractic Drugs)

    Peripheral Anxiolytics

    Comparison of Antianxiety Drugs

    7 Tricyclic Antidepressants

    Introduction

    Pharmacology

    Pharmacokinetics

    Clinical Use

    Introduction of Amitriptyline

    Other Tricyclic Antidepressant Drugs

    Comparisons Between Tricyclic Drugs and Other Antidepressive Treatments

    Tricyclic Drugs in the Treatment of Enuresis

    General Topics Concerning the Tricyclic Drugs

    Unwanted Effects

    8 New Generation of Antidepressants

    Tricyclic Antidepressants

    MAO Inhibitors

    Maprotiline

    Mianserin

    Viloxazine

    Flupenthixol

    Nomifensine

    Trazadone

    Zimelidine

    Comments

    Summary

    9 Monoamine Oxidase Inhibitors and Amine Precursors

    Pharmacology

    Pharmacokinetics

    Clinical Use

    Dosage and Clinical Response

    Unwanted Effects

    Individual Monoamine Oxidase Inhibitors

    Main Clinical Indications for Maois

    Amine Precursors

    10 Lithium Carbonate

    Introduction and Historical Aspects

    Pharmacology

    Pharmacokinetics

    Determination of Lithium Concentration

    Lithium Preparations

    Clinical Use

    Treatment of Depression with Lithium

    Lithium and Schizoaffective Disorders

    Lithium and Other Conditions

    Unwanted Effects

    Drug Interactions

    Unwanted and Toxic Effects of Lithium

    11 Psychostimulants

    Introduction

    Pharmacology

    Pharmacokinetics

    Clinical Efficacy

    Adverse Effects

    Methylphenidate

    Other Psychostimulants

    Fenfluramine

    Caffeine

    Drug Interactions

    12 Drugs of Dependence

    Controlled Drugs

    Opiate Drugs

    Tobacco Smoking and Nicotine Dependence

    Amphetamines

    Hallucinogens

    Solvent Abuse

    Minor Analgesic Abuse

    Non-Barbiturate Sedatives

    Barbiturates

    Cannabis

    Cocaine

    13 Alcohol

    Historical Background

    Ethanol Metabolism

    Ethanol Oxidation

    Problem Drinking

    Tolerance and Pharmacological Dependence

    Alcohol and Women

    Ethanol and the Neuronal Membrane

    The Fetal Alcohol Syndrome

    Hangover and the Role of Congeners

    Clinical Use of Ethanol

    Drug Interactions

    Drug Treatment for Problem Drinking

    14 Drugs in Child Psychiatry

    Pharmacokinetics

    Pharmacodynamics

    Antianxiety Drugs

    Tricyclic Antidepressants

    Monoamine Oxidase Inhibitors

    Amine Precursors

    Lithium Carbonate

    Psychostimulants

    Summary of Clinical Use

    Unwanted Effects of Psychotropic Drugs in Children

    15 Drugs in Psychogeriatrics

    Introduction

    Pharmacokinetic and Pharmacodynamic Aspects of Aging

    Other Aspects of Aging of Relevance to Psychotropic Drug Therapy

    Unwanted Effects of Psychotropic Drugs—Some General Principles

    Antidepressant Drugs and the Treatment of Depression

    Minor Tranquillizers and the Treatment of Anxiety and Insomnia

    Major Tranquillizers and the Treatment of Paranoid States

    The Drug Treatment of Organic Brain Syndrome

    Lithium and the Treatment of Mania and Recurrent Depression

    Non-Psychotropic Drugs Causing Psychiatric Problems

    Conclusions

    16 Other Uses of Psychotropic Drugs in Psychiatry

    Anorexia Nervosa

    Obesity

    Sexual Disorders

    Drugs to Improve Sexual Performance

    Other Uses of Hormones in Psychiatry

    Index of Drug Interactions

    Index of International Trade Names

    Subject Index


Product details

  • No. of pages: 454
  • Language: English
  • Copyright: © Butterworth-Heinemann 1983
  • Published: February 2, 1983
  • Imprint: Butterworth-Heinemann
  • eBook ISBN: 9781483191935

About the Author

Unknown Author

Dr. Sam Stuart is a physiotherapist and a research Fellow within the Balance Disorders Laboratory, OHSU. His work focuses on vision, cognition and gait in neurological disorders, examining how technology-based interventions influence these factors. He has published extensively in world leading clinical and engineering journals focusing on a broad range of activities such as real-world data analytics, algorithm development for wearable technology and provided expert opinion on technology for concussion assessment for robust player management. He is currently a guest editor for special issues (sports medicine and transcranial direct current stimulation for motor rehabilitation) within Physiological Measurement and Journal of NeuroEngineering and Rehabilitation, respectively.

Affiliations and Expertise

Senior Research Fellow, Department of Sport, Exercise and Rehabilitation, Northumbria University, UK Honorary Physiotherapist, Northumbria Healthcare NHS Foundation Trust, North Shields, UK

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