Drug Discovery and Development - 2nd Edition - ISBN: 9780702042997, 9780702053160

Drug Discovery and Development

2nd Edition

Technology in Transition

Authors: Raymond Hill
Paperback ISBN: 9780702042997
eBook ISBN: 9780702053160
Imprint: Churchill Livingstone
Published Date: 30th August 2012
Page Count: 368

Table of Contents

Contents

SECTION 1

INTRODUCTION AND BACKGROUND

1. The development of the pharmaceutical industry 

H P Rang

2. The nature of disease and the purpose of therapy 

H P Rang, R G Hill

3. Therapeutic modalities 

H P Rang, H LeVine, R G Hill

SECTION 2

DRUG DISCOVERY

4. The drug discovery process: general principles and some case histories 

H P Rang, R G Hill

5. Choosing the project 

H P Rang, R G Hill

6. Choosing the target 

H P Rang, R G Hill

7. The role of information, bioinformatics and genomics  

B Robson, R McBurney

8. High-throughput screening 

D Cronk

9. The role of medicinal chemistry in the drug discovery process 

P Beswick, A Naylor

10. DMPK optimization strategy in drug discovery 

P G Ballard, P Brassil, K H Bui, H Dolgos, C Petersson, A Tunek, P J H Webborn

11. Pharmacology: its role in drug discovery 

H P Rang

12. Biopharmaceuticals 

H LeVine

13. Scaffolds: Small globular proteins as antibody substitutes  

D Grabulovski, J Bertschinger

SECTION 3

DRUG DEVELOPMENT

14. Drug development: introduction

H P Rang, R G Hil

Details

No. of pages:
368
Language:
English
Copyright:
© Churchill Livingstone 2012
Published:
Imprint:
Churchill Livingstone
eBook ISBN:
9780702053160
Paperback ISBN:
9780702042997

About the Author

Raymond Hill

Affiliations and Expertise

President, British Pharmacological Society, London, UK