Drug Design - 1st Edition - ISBN: 9780120603077, 9781483216096

Drug Design

1st Edition

Medicinal Chemistry: A Series of Monographs, Vol. 7

Editors: E. J. Ariëns
eBook ISBN: 9781483216096
Imprint: Academic Press
Published Date: 28th January 1976
Page Count: 312
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Drug Design, Volume VII covers the design of agents such as blood substitutes, pesticides derived from insect pheromones, and herbicides related to the auxin-type plant hormones. The book discusses the design of artificial blood substitutes and auxin-type herbicides; the use of insect pheromones as a basis for the development of more effective selective pest control agents; and the development and application of new steric substituent parameters in drug design.
The text also describes the use of computer technology in drug design. Pharmacologists, chemists, biochemists, and people involved in drug design and manufacture will find the book invaluable.

Table of Contents

List of Contributors Preface Contents of Other Volumes Chapter 1. The Design of Artificial Blood Substitutes I. Introduction II. Constituents III. Formulation of Artificial Blood Substitutes IV. Preparation of Perfluorochemical-Type Artificial Blood Substitutes V. Testing Procedures VI. Biological Considerations VII. Potential and Summary References Chapter 2. Insect Pheromones as a Basis for the Development of More Effective Selective Pest Control Agents I. Introduction II. Terminology III. Identification of Pheromones IV. Sex Pheromones of Lepidoptera V. Pheromones and Food Attractants of Termites VI. Ant Trail Pheromones and Related Semiochemicals VII. Application of Pheromones and Their Analogs in Pest Control VIII. Prospects for Designing New Compounds with Pheromonal Activities (Parapheromones) References Chapter 3. The Design of Auxin-Type Herbicides I. Introduction II. Natural Plant Growth Regulators III. Synthetic Growth Regulators Related to Indole-3-Acetic Acid IV. Other Synthetic Auxins References Chapter 4. Development and Application of New Steric Substituent Parameters in Drug Design I. Introduction II. Development of the New Steric Parameters III. Use of the New Steric Parameters IV. Scope and Limitations References Chapter 5. Computer Technology in Drug Design I. Introduction II. Computer Intelligence Applied to Drug Design III. Conclusion Appendix References Index


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© Academic Press 1976
Academic Press
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E. J. Ariëns

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