Drug Design - 1st Edition - ISBN: 9780120603077, 9781483216096

Drug Design

1st Edition

Medicinal Chemistry: A Series of Monographs, Vol. 7

Editors: E. J. Ariëns
eBook ISBN: 9781483216096
Imprint: Academic Press
Published Date: 28th January 1976
Page Count: 312
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Description

Drug Design, Volume VII covers the design of agents such as blood substitutes, pesticides derived from insect pheromones, and herbicides related to the auxin-type plant hormones. The book discusses the design of artificial blood substitutes and auxin-type herbicides; the use of insect pheromones as a basis for the development of more effective selective pest control agents; and the development and application of new steric substituent parameters in drug design.
The text also describes the use of computer technology in drug design. Pharmacologists, chemists, biochemists, and people involved in drug design and manufacture will find the book invaluable.

Table of Contents


List of Contributors

Preface

Contents of Other Volumes

Chapter 1. The Design of Artificial Blood Substitutes

I. Introduction

II. Constituents

III. Formulation of Artificial Blood Substitutes

IV. Preparation of Perfluorochemical-Type Artificial Blood Substitutes

V. Testing Procedures

VI. Biological Considerations

VII. Potential and Summary

References

Chapter 2. Insect Pheromones as a Basis for the Development of More Effective Selective Pest Control Agents

I. Introduction

II. Terminology

III. Identification of Pheromones

IV. Sex Pheromones of Lepidoptera

V. Pheromones and Food Attractants of Termites

VI. Ant Trail Pheromones and Related Semiochemicals

VII. Application of Pheromones and Their Analogs in Pest Control

VIII. Prospects for Designing New Compounds with Pheromonal Activities (Parapheromones)

References

Chapter 3. The Design of Auxin-Type Herbicides

I. Introduction

II. Natural Plant Growth Regulators

III. Synthetic Growth Regulators Related to Indole-3-Acetic Acid

IV. Other Synthetic Auxins

References

Chapter 4. Development and Application of New Steric Substituent Parameters in Drug Design

I. Introduction

II. Development of the New Steric Parameters

III. Use of the New Steric Parameters

IV. Scope and Limitations

References

Chapter 5. Computer Technology in Drug Design

I. Introduction

II. Computer Intelligence Applied to Drug Design

III. Conclusion

Appendix

References

Index




Details

No. of pages:
312
Language:
English
Copyright:
© Academic Press 1976
Published:
Imprint:
Academic Press
eBook ISBN:
9781483216096

About the Editor

E. J. Ariëns