Drug Delivery Aspects

Drug Delivery Aspects reviews additional features of drug delivery systems, along with the standard formulation development, like preclinical testing, conversion into solid dosage forms, roles of excipients and polymers used on stability and sterile processing. There is a focus on formulation engineering and related large scale (GMP) manufacturing, regulatory, and functional aspects of drug delivery systems. A detailed discussion on biologics and vaccines gives insights to readers on new developments in this direction.

The series Expectations and Realities of Multifunctional Drug Delivery Systems examines the fabrication, optimization, biological aspects, regulatory and clinical success of wide range of drug delivery carriers. This series reviews multifunctionality and applications of drug delivery systems, industrial trends, regulatory challenges and in vivo success stories. Throughout the volumes discussions on diverse aspects of drug delivery carriers, such as clinical, engineering, and regulatory, facilitate insight sharing across expertise area and form a link for collaborations between industry-academic scientists and clinical researchers.

Expectations and Realities of Multifunctional Drug Delivery Systems connects formulation scientists, regulatory experts, engineers, clinical experts and regulatory stake holders. The wide scope of the book ensures it as a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about drug delivery systems.

• Encompasses engineering and large-scale manufacturing of nanocarriers
• Considers preclinical, regulatory and ethical guidelines on nanoparticles
• Contains in-depth discussions on delivery of biologics, vaccines and sterilisation
• Industrial view on solid dispersions, milling techniques

Pharmaceutical Scientists in academia and industry; pharmacologists; regulatory experts; bioengineers

1. Versatile hyaluronic acid nanoparticles for improved drug delivery
   Mona M.A. Abdel-Mottaleb, Hend Abd-Allah, Riham I. El-Gogary, and Maha Nasr
   2. Preclinical testing—Understanding the basics first
   Ranjita Shegokar
   3. Aqueous polymeric coatings: New opportunities in drug delivery systems
   Abid Riaz Ahmed, Joana Portugal Mota, Ahmad Abdul-Wahhab Shahba, and Muhammad Irfan
   4. Large-scale manufacturing of nanoparticles—An industrial outlook
   Ranjita Shegokar and Mostafa Nakach
   5. The role of polymers and excipients in developing amorphous solid dispersions: An industrial perspective
   Vaibhav Sihorkar and Thomas Durig
   6. Biologics: Delivery options and formulation development strategies
   Ridahunlang Nongkhlaw, Parameswar Patra, Akash Chavrasiya, Nirmal Jayabalan, and Sachin Dubey
   7. The regulatory and ethical issues in nanoparticles, materials and particles (NMP) research
   J. Dias-Ferreira, Ranjita Shegokar, A. Santini, and E.B. Souto
   8. Sterile procedures for pharmaceutical dosage forms
   Sarabjit Singh and Dharmesh Mehta
   9. Vaccine delivery strategies against botulism
   Yongyong Yan, Diana Diaz-Arevalo, Haiyan Wang, Yanping Chen, and Mingtao Zeng
   10. Nanotechnological approaches for delivery of antiinflammatory drugs
   Anđelka B. Kovacevic
   11. Food to medicine transformation of stilbenoid vesicular and lipid-based nanocarriers: Technological advances
   Sara M. Abdel Samie and Maha Nasr