Drug Delivery Aspects

Drug Delivery Aspects

Volume 4: Expectations and Realities of Multifunctional Drug Delivery Systems

1st Edition - March 27, 2020

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  • Editor: Ranjita Shegokar
  • eBook ISBN: 9780128218501
  • Paperback ISBN: 9780128212226

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Drug Delivery Aspects reviews additional features of drug delivery systems, along with the standard formulation development, like preclinical testing, conversion into solid dosage forms, roles of excipients and polymers used on stability and sterile processing. There is a focus on formulation engineering and related large scale (GMP) manufacturing, regulatory, and functional aspects of drug delivery systems. A detailed discussion on biologics and vaccines gives insights to readers on new developments in this direction. The series Expectations and Realities of Multifunctional Drug Delivery Systems examines the fabrication, optimization, biological aspects, regulatory and clinical success of wide range of drug delivery carriers. This series reviews multifunctionality and applications of drug delivery systems, industrial trends, regulatory challenges and in vivo success stories. Throughout the volumes discussions on diverse aspects of drug delivery carriers, such as clinical, engineering, and regulatory, facilitate insight sharing across expertise area and form a link for collaborations between industry-academic scientists and clinical researchers. Expectations and Realities of Multifunctional Drug Delivery Systems connects formulation scientists, regulatory experts, engineers, clinical experts and regulatory stake holders. The wide scope of the book ensures it as a valuable reference resource for researchers in both academia and the pharmaceutical industry who want to learn more about drug delivery systems.

Key Features

  • Encompasses engineering and large-scale manufacturing of nanocarriers
  • Considers preclinical, regulatory and ethical guidelines on nanoparticles
  • Contains in-depth discussions on delivery of biologics, vaccines and sterilisation
  • Industrial view on solid dispersions, milling techniques


Pharmaceutical Scientists in academia and industry; pharmacologists; regulatory experts; bioengineers

Table of Contents

  • 1. Versatile hyaluronic acid nanoparticles for improved drug delivery
    Mona M.A. Abdel-Mottaleb, Hend Abd-Allah, Riham I. El-Gogary, and Maha Nasr
    2. Preclinical testing—Understanding the basics first
    Ranjita Shegokar
    3. Aqueous polymeric coatings: New opportunities in drug delivery systems
    Abid Riaz Ahmed, Joana Portugal Mota, Ahmad Abdul-Wahhab Shahba, and Muhammad Irfan
    4. Large-scale manufacturing of nanoparticles—An industrial outlook
    Ranjita Shegokar and Mostafa Nakach
    5. The role of polymers and excipients in developing amorphous solid dispersions: An industrial perspective
    Vaibhav Sihorkar and Thomas Durig
    6. Biologics: Delivery options and formulation development strategies
    Ridahunlang Nongkhlaw, Parameswar Patra, Akash Chavrasiya, Nirmal Jayabalan, and Sachin Dubey
    7. The regulatory and ethical issues in nanoparticles, materials and particles (NMP) research
    J. Dias-Ferreira, Ranjita Shegokar, A. Santini, and E.B. Souto
    8. Sterile procedures for pharmaceutical dosage forms
    Sarabjit Singh and Dharmesh Mehta
    9. Vaccine delivery strategies against botulism
    Yongyong Yan, Diana Diaz-Arevalo, Haiyan Wang, Yanping Chen, and Mingtao Zeng
    10. Nanotechnological approaches for delivery of antiinflammatory drugs
    Anđelka B. Kovacevic
    11. Food to medicine transformation of stilbenoid vesicular and lipid-based nanocarriers: Technological advances
    Sara M. Abdel Samie and Maha Nasr

Product details

  • No. of pages: 266
  • Language: English
  • Copyright: © Elsevier 2020
  • Published: March 27, 2020
  • Imprint: Elsevier
  • eBook ISBN: 9780128218501
  • Paperback ISBN: 9780128212226

About the Editor

Ranjita Shegokar

Dr. Ranjita Shegokar holds a PhD degree in Pharmaceutical Technology from the SNDT University, India, and has been postdoctoral researcher in the Department of Pharmaceutics, Biopharmaceutics and NutriCosmetics at Free University of Berlin, Germany. Since last 8 years she is working in the pharmaceutical industry in various technical/R&D roles. Currently, she serves as Director of Pharma Business Unit at Capnomed GmbH, Germany. She has authored many research articles, book chapters, and presented several research papers in conferences. She has filed multiple patent application in area of drug delivery and drug targeting. She received several national and international awards for her research. Her areas of interest include polymeric nanoparticles, nanocrystals, lipid nanoparticles (SLNs/NLCs), nanoemulsions and role of excipients in delivery systems.

Affiliations and Expertise

Capnomed GmbH, Tubingen, Germany

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