DNA Repair

DNA Repair

1st Edition - October 15, 2019

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  • Editors: Linlin Zhao, Laurie S. Kaguni
  • eBook ISBN: 9780128173978
  • Hardcover ISBN: 9780128173961

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Description

DNA Repair, Volume 45 in The Enzymes series highlights new advances in the field, with this new volume presenting interesting chapters on DNA polymerase beta and other gap-filling enzymes in mammalian base excision repair, Translesion polymerases, mechanism and function, The Rev1-Polζ Mutasome: Structure and Interactions in Translesion Synthesis, Challenges for base excision repair enzymes: acquiring access to damaged DNA in chromatin Nucleotide excision repair, DNA damage recognition mechanisms in mammalian nucleotide excision repair, Advances in understanding DNA mismatch repair, and more.

Key Features

  • Provides the authority and expertise of leading contributors from an international board of authors
  • Presents the latest release in The Enzymes series

Readership

Specialists in the field of Enzymes

Table of Contents

  • 1. DNA polymerase beta and other gap-filling enzymes in mammalian base excision repair
    William A. Beard and Samuel H. Wilson
    2. Challenges for base excision repair enzymes: Acquiring access to damaged DNA in chromatin
    Chuxuan Li and Sarah Delaney
    3. Damage removal and gap filling in nucleotide excision repair
    Michael G. Kemp
    4. Mechanism and regulation of DNA damage recognition in mammalian nucleotide excision repair
    Kaoru Sugasawa
    5. The Rev1-Polζ translesion synthesis mutasome: Structure, interactions and inhibition
    Alessandro A. Rizzo and Dmitry M. Korzhnev
    6. Contacts and context that regulate DNA helicase unwinding and replisome progression
    Himasha M. Perera, Megan S. Behrmann, Joy M. Hoang, Wezley C. Griffin and Michael A. Trakselis
    7. Iron-sulfur clusters in nucleic acid metabolism: Varying roles of ancient cofactors
    Yara Khodour, Laurie S. Kaguni and Johnny Stiban
    8. Enzymology of mitochondrial DNA repair
    Rebeca R. Alencar, Caio M.P.F. Batalha, Thiago S. Freire and Nadja C. Souza-Pinto
    9. Mechanism of DNA primer synthesis by human PrimPol
    Luis Blanco, Patricia A. Calvo, Alberto Diaz-Talavera, Gustavo Carvalho, Nieves Calero, Ana Martínez-Carrón, Cristina Velázquez-Ruiz, Sabina Villadangos, Susana Guerra and María I. Martínez-Jiménez
    10. Mitochondrial DNA degradation: A quality control measure for mitochondrial genome maintenance and stress response
    Linlin Zhao

Product details

  • No. of pages: 354
  • Language: English
  • Copyright: © Academic Press 2019
  • Published: October 15, 2019
  • Imprint: Academic Press
  • eBook ISBN: 9780128173978
  • Hardcover ISBN: 9780128173961

About the Serial Volume Editors

Linlin Zhao

Linlin Zhao is at University of California, Riverside, USA

Affiliations and Expertise

University of California, Riverside, USA

Laurie S. Kaguni

Laurie S. Kaguni is at Michigan State University, MI, USA

Affiliations and Expertise

Michigan State University, MI, USA

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