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Disease Modelling and Public Health, Part B - 1st Edition - ISBN: 9780444639752, 9780444639769

Disease Modelling and Public Health, Part B, Volume 37

1st Edition

Serial Volume Editors: Arni Srinivasa Rao Saumyadipta Pyne C.R. Rao
Hardcover ISBN: 9780444639752
eBook ISBN: 9780444639769
Imprint: North Holland
Published Date: 31st October 2017
Page Count: 390
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Table of Contents

Section VI : Statistical Methodologies
1. Imputation of Area-Level Covariates by Registry Linking
J.S. Rao and Jie Fan
2. Asymptotic Approaches to Discovering Cancer Genomic Signatures
Maciej Pietrzak and Grzegorz A. Rempala
3. Emerging Statistical Methodologies in the Field of Microbiome Studies
Siddhartha Mandal

Section VII : Advanced Mathematical Methods
4. Reaction–Diffusion Equations and Their Application on Bacterial Communication
Christina Kuttler
5. Hepatitis C Virus (HCV) Treatment as Prevention: Epidemic and Cost-Effectiveness Modeling
Natasha K. Martin and Lara K. Marquez
6. Mathematical Modeling of Mass Screening and Parameter Estimation
Masayuki Kakehashi and Miwako Tsunematsu
7. Inferring Patterns, Dynamics, and Model-Based Metrics of Epidemiological Risks of Neglected Tropical Diseases
Anuj Mubayi
8. Theory and Modeling for Time Required to Vaccinate a Population in an Epidemic
Taejin Lee, Kurien Thomas and Arni S.R. Srinivasa Rao

Section VIII : Public Health and Epidemic Data Modeling
9. Frailty Models in Public Health
David D. Hanagal
10. Structural Nested Mean Models and History-Adjusted Marginal Structural Models for Time-Varying Effect Modification: An Application to Dental Data
Murthy N. Mittinty
11. Conditional Growth Models: An Exposition and Some Extensions
Clive Osmond and Caroline H.D. Fall
12. Parametric Model to Predict H1N1 Influenza in Vellore District, Tamil Nadu, India
Daphne Lopez and Gunasekaran Manogaran
13. Public Health Eye Care: Modeling Techniques to Translate Evidence Into Effective Action
Gudlavalleti V.S. Murthy and Neena S. John
14. Individual-Based Models for Public Health
Benjamin Roche and Raphaël Duboz


Handbook of Statistics: Disease Modelling and Public Health, Part B, Volume 37 addresses new challenges in existing and emerging diseases. As a two part volume, this title covers an extensive range of techniques in the field, with this book including chapters on Reaction diffusion equations and their application on bacterial communication, Spike and slab methods in disease modeling, Mathematical modeling of mass screening and parameter estimation, Individual-based and agent-based models for infectious disease transmission and evolution: an overview, and a section on Visual Clustering of Static and Dynamic High Dimensional Data.

This volume covers the lack of availability of complete data relating to disease symptoms and disease epidemiology, one of the biggest challenges facing vaccine developers, public health planners, epidemiologists and health sector researchers.

Key Features

  • Presents a comprehensive, two-part volume written by leading subject experts
  • Provides a unique breadth and depth of content coverage
  • Addresses the most cutting-edge developments in the field


Researchers in academia, industry and government, as well as students in statistics, health professionals, clinicians, data scientists and modellers


No. of pages:
© North Holland 2017
31st October 2017
North Holland
Hardcover ISBN:
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Ratings and Reviews

About the Serial Volume Editors

Arni Srinivasa Rao

Arni Srinivasa Rao

Arni S.R. Srinivasa Rao is a mathematical modeler and probability researcher who is a Professor in the Medical College of Georgia, Augusta University. He is the Director of Laboratory for Theory and Mathematical Modeling housed within the Division of Infectious Diseases, Medical College of Georgia, Augusta University. Previously, Dr. Rao conducted research and/or taught at Mathematical Institute, University of Oxford (2003, 2005-07), Indian Statistical Institute (1998-2002, 2006-2012), Indian Institute of Science (2002-04), University of Guelph (2004-06). Until 2012, Dr. Rao held a permanent faculty position at the Indian Statistical Institute. He has won the Heiwa-Nakajima Award (Japan) and Fast Track Young Scientists Fellowship in Mathematical Sciences (DST, New Delhi). Dr. Rao also proved a major theorem in stationary population models (Rao-Carey Theorem), Rao-Carey Partition Theorem in Populations and developed mathematical modeling based policies for the spread of diseases like HIV, H5N1,COVID-19 etc, He developed a new set of network models for understanding avian pathogen biology on grid graphs (these were called chicken walk models) and received wide coverage in the science media. Currently, he is researching in deep learning and artificial intelligence techniques to be used in medicine.

Affiliations and Expertise

Medical College of Georgia, and Professor, Department of Mathematics, Augusta University, Georgia, USA

Saumyadipta Pyne

PhD, Professor, Indian Institute of Public Health, Hyderabad, India

Affiliations and Expertise

Indian Institute of Public Health, Hyderabad, India

C.R. Rao

C. R. Rao is a world famous statistician who earned a place in the history of statistics as one of those “who developed statistics from its adhoc origins into a firmly grounded mathematical science.”

He was employed at the Indian Statistical Institute (ISI) in 1943 as a research scholar after obtaining an MA degree in mathematics with a first class and first rank from Andhra University in1941 and MA degree in statistics from Calcutta University in 1943 with a first class, first rank, gold medal and record marks which remain unbroken during the last 73 years.

“At the age of 28 he was made a full professor at ISI in recognition of his creativity.” While at ISI, Rao went to Cambridge University (CU) in 1946 on an invitation to work on an anthropometric project using the methodology developed at ISI. Rao worked in the museum of archeology and anthropology in Duckworth laboratory of CU during 1946-1948 as a paid visiting scholar. The results were reported in the book “Ancient Inhabitants of Jebel Moya” published by the Cambridge Press under the joint authorship of Rao and two anthropologists. On the basis of work done at CU during the two year period, 1946-1948, Rao earned a Ph.D. degree and a few years later Sc.D. degree of CU and the rare honor of life fellowship of Kings College, Cambridge.

He retired from ISI in 1980 at the mandatory age of 60 after working for 40 years during which period he developed ISI as an international center for statistical education and research. He also took an active part in establishing state statistical bureaus to collect local statistics and transmitting them to Central Statistical Organization in New Delhi. Rao played a pivitol role in launching undergraduate and postgraduate courses at ISI. He is the author of 475 research publications and several breakthrough papers contributing to statistical theory and methodology for applications to problems in all areas of human endeavor. There are a number of classical statistical terms named after him, the most popular of which are Cramer-Rao inequality, Rao-Blackwellization, Rao’s Orthogonal arrays used in quality control, Rao’s score test, Rao’s Quadratic Entropy used in ecological work, Rao’s metric and distance which are incorporated in most statistical books.

He is the author of 10 books, of which two important books are, Linear Statistical Inference which is translated into German, Russian, Czec, Polish and Japanese languages,and Statistics and Truth which is translated into, French, German, Japanese, Mainland Chinese, Taiwan Chinese, Turkish and Korean languages.

He directed the research work of 50 students for the Ph.D. degrees who in turn produced 500 Ph.D.’s. Rao received 38 hon. Doctorate degree from universities in 19 countries spanning 6 continents. He received the highest awards in statistics in USA,UK and India: National Medal of Science awarded by the president of USA, Indian National Medal of Science awarded by the Prime Minister of India and the Guy Medal in Gold awarded by the Royal Statistical Society, UK. Rao was a recipient of the first batch of Bhatnagar awards in 1959 for mathematical sciences and and numerous medals in India and abroad from Science Academies. He is a Fellow of Royal Society (FRS),UK, and member of National Academy of Sciences, USA, Lithuania and Europe. In his honor a research Institute named as CRRAO ADVANCED INSTITUTE OF MATHEMATICS, STATISTICS AND COMPUTER SCIENCE was established in the campus of Hyderabad University.

Affiliations and Expertise

University of Hyderabad Campus, India