Digital Health

Digital Health: Mobile and Wearable Devices for Participatory Health Applications is a key reference for engineering or clinical professionals who are considering the development or implementation of mobile and wearable solutions in the healthcare domain. The book presents a comprehensive overview of devices and appropriateness for the respective applications. It also explores the ethical, privacy and cybersecurity aspects inherent in networked and mobile technologies. The book also offers expert perspectives on various approaches to the implementation and integration of these devices and applications across all areas of healthcare.

The book is designed with a multidisciplinary audience in mind, from software developers and biomedical engineers who are designing these devices, to clinical professionals working with patients and engineers on device testing, human factors design, and user engagement/compliance.

• Presents an overview of the most important aspects of mHealth, from patient privacy and data security, to the development and implementation of networks, systems and devices
• Provides a toolbox for stakeholders involved in decision-making, surrounding the design, development and implementation of mHealth solutions
• Includes case studies, key references and insights from a wide range of global experts

Graduate students, researchers, and professionals in biomedical engineering, clinical engineering, computer science, and medical informatics, working with the design, development, and implementation of mobile and wearable medical devices. Healthcare professionals (clinicians, nurses) working with engineers on the implementation and human factors design of mobile and wearable medical devices

Contributors ix

Preface xi

1. Introduction to digital health approach and mHealth applications

for participatory health 1

Mohy Uddin and Shabbir Syed-Abdul

References 5

2. Digital health in the era of personalized healthcare:

opportunities and challenges for bringing research and patient

care to a new level 7

Jorge Cancela, Iliàs Charlafti, Seya Colloud and Catherine Wu

1. An introduction to the promise of the digital era 7

2. Opportunities for digital health in the context of personalized healthcare 9

3. Challenges throughout the life cycle of digital health solutions 19

4. Conclusions 27

Acknowledgments 28

Conflicts of interest 28

References 28

3. Digital health regulatory and policy considerations 33

Robert Jarrin, JD and Kapil Parakh, MD, MPH, PhD

1. Learning objectives 33

2. Flow and rationale of the chapter structure 34

3. Fundamentals of government and healthcare 34

4. How the US federal government is organized 34

5. Health and human services law, regulations, and policy 35

6. Government and its impact on digital health 36

7. International regulation of digital health 48

8. Conclusion 49

9. Description of pedagogical elements (e.g., case study, infographics

required, key references) 49

4. How to use the Integrated-Change Model to design digital

health programs 51

Kei Long Cheung, Santiago Hors-Fraile and Hein de Vries

1. Theory to understand health behavior 52

2. Integrated-Change Model 56

3. Digital health and tailoring 58

4. Pragmatic methodology to design digital health 59

5. Conclusions 64

References 64

5. Illustration of tailored digital health and potential new avenues 67

Kei Long Cheung, Santiago Hors-Fraile and Hein de Vries

1. Case of tobacco smoking 68

2. New avenues of computer tailoring 72

3. Use of artificial intelligence to progress computer tailoring 72

4. Conclusions 75

References 76

6. Wearables, smartphones, and artificial intelligence for digital

phenotyping and health 79

Ignacio Perez-Pozuelo, Dimitris Spathis, Emma A.D. Clifton and

Cecilia Mascolo

1. Towards digital phenotyping 79

2. Mobile health 80

3. Artificial intelligence 83

4. Toward objective measures of physical behaviors in epidemiology 85

5. Conclusion 95

Acknowledgments 96

References 96

7. mHealth for research: participatory research applications to

gain disease insights 101

Ipek Ensari and Noémie Elhadad

Learning objectives 101

1. Background on research mHealth applications 102

2. User engagement and participatory design in mHealth research 103

3. User engagement strategies and metrics 108

4. Making disease discoveries and insights from self-tracked data 116

5. Conclusion and discussion 118

Acknowledgments 119

References 119

8. Mobile health apps: the quest from laboratory to the market 125

Juan José Lull, Antonio Martínez-Millana and Vicente Traver

1. Introduction 126

2. Business model 126

3. Context: business models 127

4. From business models to products 128

5. Product dependencies 129

6. Marketing strategy 130

7. Intellectual property rights 131

8. Business scenarios 132

9. Distribution: exploitation models 136

10. Product use cases 137

11. Conclusion 143

References 143

9. mHealth in public health sector: challenges and opportunities

in low- and middle-income countries: a case study of Sri Lanka 145

Pamod Amarakoon, Roshan Hewapathirana and Vajira H.W. Dissanayake

1. Introduction 146

2. Use of mobile technology in the public health sector: Asian Regional

context 150

3. Opportunities 152

4. Challenges 156

References 163

10. Sustainability of mHealth solutions for healthcare system

strengthening 165

Mohamed-Amine Choukou

1. Introduction 165

2. mHealth solutions: disruptive technologies as a remedy for a system

under strain 167

3. Digital twin technology as an example of technology-driven healthcare

system change 170

4. mHealth solutions sustainability 171

5. mHealth solutions: path to sustainability 173

6. Conclusion and future directions 175

References 181

Index 185