Diagnostic Molecular Biology - 1st Edition - ISBN: 9780128028230

Diagnostic Molecular Biology

1st Edition

Authors: Chang-Hui Shen
Paperback ISBN: 9780128028230
Imprint: Academic Press
Published Date: 1st June 2018
Page Count: 448
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Diagnostic Molecular Biology describes the fundamentals of molecular biology in a clear, concise manner to help readers comprehend this complex subject. Each technique is explained within a conceptual framework to enhance understanding, and current applications of clinical laboratory techniques are covered in detail. This targeted approach covers the principles of molecular biology, including the basic knowledge of nucleic acids, proteins, chromosomes, and the basic techniques and instrumentations that are commonly used in the field of molecular biology. In addition, detailed procedures and explanations, and the applications of the principle and techniques currently employed in the clinical laboratory are covered.

Key Features

  • Provides an understanding of what techniques are used to diagnosis at the molecular level
  • Explains how to use information technology to communicate and assess results in the lab
  • Places protocols into context with practical applications


Researchers and technicians in the lab, pathologists, and students in molecular biology and microbiology

Table of Contents

Part I
1. Introduction
2. Genes
3. Nucleic acids based cellular activities
4. Genes encode polypeptides
5. Genome

Part II
6. Extraction and purification of nucleic acids and proteins
7. Detection and analysis of nucleic acids and proteins
8. Characterization of nucleic acids and proteins
9. Amplification of nucleic acids
10. Genes and genomes sequencing techniques
11. Techniques in studying gene expression and function
12. Techniques in studying genomes

Part III
13. Techniques in human identification
14. Molecular diagnosis of mutation and inherited diseases
15. Molecular diagnosis of microorganisms and infectious diseases
16. Molecular diagnosis of cancers
17. Safety and quality management in clinical medical laboratory


No. of pages:
© Academic Press 2018
Academic Press
Paperback ISBN:

About the Author

Chang-Hui Shen

Chang-Hui Shen graduated from Nation Chung-Hsing University, Taiwan, with both a BS and MS, earning his PhD from the University of Edinburgh. he has been a visiting fellow of the National Institues of Health, since moving onto the College of Staten Island, first as an Assitant Professor, presently as an Associate Professor.

Affiliations and Expertise

Associate Professor and Deputy Chair, Biology Department, College of Staten Island, CUNY Biochemistry/Biology Ph.D. Program, CUNY Graduate Center Institute for Macromolecular Assemblies, New York, USA

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