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Diagnosis and Management in Parkinson's Disease - 1st Edition - ISBN: 9780128159460, 9780128159477

Diagnosis and Management in Parkinson's Disease

1st Edition

The Neuroscience of Parkinson’s Disease, Volume 1

Editors: Colin Martin Victor Preedy
Hardcover ISBN: 9780128159460
eBook ISBN: 9780128159477
Imprint: Academic Press
Published Date: 18th September 2020
Page Count: 782
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Diagnosis and Management in Parkinson's Disease: The Neuroscience of Parkinson’s, Volume 1 provides a single source of material covering different scientific domains of neuropathology underlying this condition. The book covers a wide range of subjects and unravels the complex relationships between genetics, molecular biology, pharmaceutical chemistry, neurobiology, imaging, assessments, and treatment regimens. It fills a much-needed gap as a "one-stop" synopsis of everything concerning the neurology and neuroscience related to Parkinson’s disease, from chemicals and cells to individuals. The book is an invaluable resource for neuroscientists, neurologists, and anyone in the field.

Key Features

  • Offers the most comprehensive coverage of a broad range of topics related to Parkinson's disease
  • Serves as a foundational collection for neuroscientists and neurologists on the biology of disease and brain dysfunction
  • Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding
  • Features preclinical and clinical studies to help researchers map out key areas for research and further clinical recommendations
  • Serves as a "one-stop" source for everything you need to know about Parkinson’s disease


Neuroscientists/neurologists, psychologists, health scientists, public health workers, research scientists, pharmacologists, and physicians. Graduate/postgraduate students, lecturers, and professors

Table of Contents

Part I: Introductory chapters and setting the scene

1. Progression of symptoms in Parkinson’s disease
Federico Paolini Paoletti, Lucia Farotti and Lucilla Parnetti

2. Cellular pathophysiology and basal ganglia dysfunction in Parkinson’s disease: an overview
K.F. Loewenbruck, F. Pan-Montojo and H. Reichmann

3. The role of environmental toxins and inflammation in Parkinson’s disease pathophysiology: a historical perspective and research-based evidence
F. Pan-Montojo, K.F. Loewenbruck and H. Reichmann

4. Environmental and genetic risk factors for Parkinson’s disease
Lazaros Belbasis, Vanesa Bellou and Evangelos Evangelou

5. Recent developments in the etiology, treatment, and potential therapeutic targets for Parkinson’s disease: a focus on biochemistry
Sapana Sameer Chaudhary, Sameer Chaudhary, Sakshi Rawat, Saieswari Natesan, Tanvee Pardeshi, Athanasios Alexiou and Ghulam Md Ashraf

6. Facial emotion recognition in Parkinson’s disease: methodological, clinical, and pathophysiological factors
Marco De Risi, Enrica Olivola, Giancarlo Di Gennaro and Nicola Modugno

7. Diurnal patterns and circadian aspects of Parkinson’s disease: retinal, hypothalamic/midbrain, and pineal participation
Gregory L. Willis

 8. Parkinson’s disease and social media
Ibrahim S. Al-Busaidi and Yassar Alamri

9. Sleep disturbances in Parkinson’s diseas
Adriano D.S. Targa, Juliane Fagotti, Patrícia Dominico, Ana Paula Chuproski and Marcelo M.S. Lima

10. Recurrent falls in people with Parkinson’s disease
Lorena Rosa S. Almeida, Serene S. Paul and Guilherme T. Valenca

11. Medical decision-making in patients with Parkinson’s disease
Janneke Koerts, Josephien Jansen, Anselm B.M. Fuermaier, Lara Tucha and Oliver Tucha

12. Visual impairment in Parkinson’s disease
Alessandro Arrigo, Alessandro Calamuneri, Emanuela Aragona, Enricomaria Mormina and Michele Gaeta

13. Autonomic problems in Parkinson’s disease: a focus on the bladder
Ryuji Sakakibara, Fuyuki Tateno, Tatsuya Yamamoto and Tomoyuki Uchiyama

14. Dementia and bladder dysfunction: a focus on treatments with anticholinergics
Ryuji Sakakibara and Fuyuki Tateno

15. Linking and comparing non-motor symptoms in aging and Parkinson’s disease
Petra Bago Rozankovic

16. Progression of motor symptoms in Parkinson’s disease
Daniela Vieira, Joana Jesus-Ribeiro and Cristina Januario

17. The stigma of Parkinson’s disease: development and implications
John T.H. Tsiang and Benjamin K.P. Woo

Part II: Biomarkers, instruments, diagnosis and assessments

18. Better neuroradiological approach for the diagnosis of early-stage Parkinson’s disease patients
Yasuaki Mizutani, Yoshiki Niimi and Tatsuro Mutoh

19. Use of positron-emission tomography as a diagnostic and differential diagnostic tool in parkinsonian syndromes
Petra Tomse, Tomaz Rus, Matej Perovnik, Chris C. Tang, David Eidelberg and Maja Trost

20. Keyboard typing for the detection of early Parkinson’s disease
Warwick R. Adams

21. Cerebrospinal fluid biomarkers of Parkinson’s disease: an update
Kanae Nagao and Peter A. LeWitt

22. Understanding Parkinson’s disease pathophysiology: clinical application of eye movement tasks and underlying neural correlates
Kikuro Fukushima, Junko Fukushima and Graham R. Barnes

23. Measuring quality of life in Parkinson’s disease
Maria Jo~ao Forjaz, Carmen Rodríguez-Blazquez and Pablo MartinezeMartin

24. Clinically assessing cognitive function in Parkinson’s disease
Megan Bakeberg, Maddeson Riley, Michelle Byrnes, Frank L. Mastaglia and Ryan S. Anderton

Part III: Pharmacological treatments, other agents and strategies

25. A new neuroprotective strategy for the drug therapy of Parkinson’s disease: Ca2þ/cAMP signaling as therapeutic targets
Afonso Caricati-Neto, Fulvio Alexandre Scorza and Leandro Bueno Bergantin

26. Dopamine agonists in treatment of Parkinson’s disease: an overview
Dan Luo, Maarten Reith and Aloke K. Dutta

27. Management with apomorphine in Parkinson’s disease
Manon Auffret, Sophie Drapier and Marc Verin

28. Management with monoamine oxidase B inhibitors in Parkinson’s disease
Thomas Muller

29. Management with antibiotics in Parkinson’s disease
Mariza Bortolanza, Bruno L. Santos-Lobato, Glauce Crivelaro Nascimento and Elaine Del-Bel

30. Intracerebroventricular administration of dopamine in Parkinson’s disease: treatment of motor fluctuations and dyskinesia
C. Laloux, C. Lachaud, C. Moreau, M. Fisichella, J.C. Devedjian, J.A. Duce and D. Devos

31. Placebo and nocebo responses in Parkinson’s disease
Fabrizio Benedetti, Elisa Carlino, Elisa Frisaldi, Alessandro Piedimonte, Maurizio Zibetti, Michele Lanotte and Leonardo Lopiano

32. Levodopa-induced dyskinesias in Parkinson’s disease
Stephanie L. Alberico and Nandakumar S. Narayanan

33. Cannabinoid receptor type 2 as a therapeutic target for Parkinson’s disease
Miguel A. Abellanas and Maria S. Aymerich

Part IV: Non-pharmacological, novel and other treatment procedures

34. Deep brain stimulation surgery in Parkinson’s disease
Lee Neilson, Jonathan Zande and Hesham Abboud

35. Gene delivery for Parkinson’s disease
Piotr Chmielarz, Anne Panhelainen, Mikko Airavaara and Andrii Domanskyi

36. Cell transplantation therapy for Parkinson’s disease
Piotr Chmielarz, Julia Konovalova and Andrii Domanskyi

37. Ursodeoxycholic and tauroursodeoxycholic acids as antiapoptotic agents: modulation of Parkinson’s disease
Noha F. Abdelkader

38. Interlinking potential therapy with botulinum neurotoxin-A and Parkinson’s disease
Andreas Wree, Alexander Hawlitschka, Carsten Holzmann, Martin Witt, Jens Kurth, Tobias Lindner, Teresa Mann and Veronica Antipova

39. Neuropeptide cocaine- and amphetamine-regulated transcript usage in Parkinson’s disease
Peizhong Mao and Yifan Mao

40. Photobiomodulation as a neuroprotective strategy for Parkinson’s disease
Claudia Petrucco, Patrick Benson, Luke Gordon, Jonathan Stone and Daniel M. Johnstone

41. Assistive technologies in Parkinson’s disease
Roongroj Bhidayasiri



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© Academic Press 2020
18th September 2020
Academic Press
Hardcover ISBN:
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About the Editors

Colin Martin

Dr. Martin is a Professor of Mental Health at Buckinghamshire New University. He is a Registered Nurse, Chartered Health Psychologist, and a Chartered Scientist. He has published or has in press well over 250 research papers and book chapters. He is a keen book author and editor having written and/or edited several books all of which reflect his diverse academic and clinical interests that examine in-depth, the interface between mental health and physical health. These outputs include the Handbook of Behavior; Food and Nutrition (2011), Perinatal Mental Health: A Clinical Guide (2012); Nanomedicine and the Nervous System (2012), and the major reference works Comprehensive Guide to Autism (2014), Diet and Nutrition in Dementia and Cognitive Decline (2015), Comprehensive Guide to Post-Traumatic Stress Disorder (2016) and Metabolism and Pathophysiology of Bariatric Surgery: Nutrition, Procedures, Outcomes, and Adverse Effects (2017).

Affiliations and Expertise

Professor of Mental Health, Bickinghamshire New University, High Wycombe, Buckinghamshire, England, United Kingdom

Victor Preedy

Dr. Preedy is a senior member of King's College London and Director of the Genomics Centre and a member of the Faculty of Life Sciences and Medicine. Professor Preedy has longstanding academic interests in substance misuse especially in relation to health and well-being. In his career Professor Preedy was Reader at the Addictive Behaviour Centre at The University of Roehampton, and also Reader at the School of Pharmacy (now part of University College London; UCL). Professor Preedy is an extremely experienced book editor, having edited influential works including but not limited to The Handbook of Alcohol Related Pathology, The Neuropathology of Drug Addictions and Substance Misuse, The Handbook of Cannabis and Related Pathologies, The Neuroscience of Cocaine, and upcoming titles The Neuroscience of Alcohol, The Neuroscience of Nicotine, and more (all Elsevier).

Affiliations and Expertise

Professor of Nutritional Biochemistry, Department of Nutrition and Dietetics, Professor of Clinical Biochemistry, Department of Clinical Biochemistry; Director of the Genomics Centre, King’s College, London, UK

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