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Diagnosis and Management in Parkinson's Disease - 1st Edition - ISBN: 9780128159460

Diagnosis and Management in Parkinson's Disease

1st Edition

The Neuroscience of Parkinson’s Disease, Volume 1

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Editors: Colin R. Martin Victor Preedy
Hardcover ISBN: 9780128159460
Imprint: Academic Press
Published Date: 7th September 2020
Page Count: 782
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Diagnosis and Management in Parkinson's Disease: The Neuroscience of Parkinson’s, Volume 1 provides a single source of material covering different scientific domains of neuropathology underlying this condition. The book covers a wide range of subjects and unravels the complex relationships between genetics, molecular biology, pharmaceutical chemistry, neurobiology, imaging, assessments, and treatment regimens. It fills a much-needed gap as a "one-stop" synopsis of everything concerning the neurology and neuroscience related to Parkinson’s disease, from chemicals and cells to individuals. The book is an invaluable resource for neuroscientists, neurologists, and anyone in the field.

Key Features

  • Offers the most comprehensive coverage of a broad range of topics related to Parkinson's disease
  • Serves as a foundational collection for neuroscientists and neurologists on the biology of disease and brain dysfunction
  • Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding
  • Features preclinical and clinical studies to help researchers map out key areas for research and further clinical recommendations
  • Serves as a "one-stop" source for everything you need to know about Parkinson’s disease


Neuroscientists/neurologists, psychologists, health scientists, public health workers, research scientists, pharmacologists, and physicians. Graduate/postgraduate students, lecturers, and professors

Table of Contents

Virginia Bottomley

I. Introductory Chapters and Setting the Scene
1. Progression of symptoms in Parkinson's disease
Lucilla Parnetti
2. Cellular pathophysiology and basal ganglia dysfunction in Parkinson's disease: An Overview
Heinz Reichmann and Kai Felix Loewenbrueck
3. The role of environmental toxins and inflammation in Parkinson’s disease pathophysiology: a historical perspective and research-based evidence
Heinz Reichmann and Kai Felix Loewenbrueck
4. Risk factors in Parkinson's Disease: genetic and nongenetic
Evangelos Evangelou
5. Recent developments in the etiology, treatment and potential therapeutic targets for Parkinson's Disease: a focus on biochemistry
Athanasios Alexiou
6. Facial emotions and Parkinson's disease
G. Di Gennaro and Marco De Risi
7. The role of the circadian system in Parkinson’s Disease
G. Willis
8. Parkinson's disease and social media
Ibrahim S. Al-Busaidi
9. Sleep in Parkinson's disease
Marcelo M. S. Lima
10. Recurrent falls in Parkinson's disease
Lorena Rosa Santos de Almeida
11. Parkinsons patients deciding their own treatment
J. Koerts
12. Visual impairment in Parkinson's disease
Alessandro Arrigo
13. Autonomic problems in Parkinson’s disease: a focus on the bladder
Ryuji Sakakibara
14. Autonomic problems in Parkinson’s disease: a focus on the bowel
Ryuji Sakakibara
15. Linking and comparing nonmotor symptoms in ageing and Parkinson’s disease
Petra Bago Rozankovic
16. Progression of motor symptoms in Parkinson's Disease
Joana Ribeiro and Daniela Vieira
17. The stigma of Parkinson's disease
Benjamin K.P. Woo

II. Biomarkers, Instruments, Diagnosis and Assessments
18. Better neuroradiological approaches for the diagnosis of early stage Parkinson's disease patients
Tatsuro Mutoh
19. Use of positron emission tomography (PET) as a diagnostic and differential diagnostic tool in Parkinsonian syndromes
Maja Trost
20. Finger typing for the detection of early Parkinson's Disease
Warwick Adams
21. CSF biomarkers of Parkinson's disease
P. Lewitt
22. Application of eye movement tasks as an aid to understanding Parkinson's disease pathophysiology
Kikuro Fukushima
23. Measuring quality of life
Pablo Martinez Martin and Camen Rodriquez-Blazquez
24. Clinically assessing cognitive function in Parkinson’s disease
Ryan Anderton

III. Pharmacological Treatments, Other Agents and Strategies
25. Good news for the drug therapy of Parkinson`s disease
L. Bergantin
26. Dopamine Agonists and Parkinson’s disease: an overview
Aloke K. Dutta
27. Management with apomorphine in Parkinson’s disease
Manon Auffret
28. Management with MAO-B Inhibitors in Parkinson’s disease
T. Mueller
29. Management with antibiotics in Parkinson’s disease
Elaine Del-Bel and Mariza Bortolanza
30. Administration of dopamine in the brain in Parkinson’s disease
David Devos
31. Placebo and nocebo effects in Parkinson's disease
Fabrizio Benedetti
32. Levodopa-induced dyskinesias
N. S. Narayanan and Stephanie Alberico
33. Cannabinoid receptor type 2 as a therapeutic target for Parkinson’s disease
Miguel Abellanas and M. Aymerich

IV. Non-Pharmacological, Novel and Other Treatment Procedures
34. Deep Brain Stimulation Surgery in Parkinson's Disease
Hesham Abboud
35. Gene delivery for Parkinson’s disease
M. Airavaara and Andrii Domanskyi
36. Transdifferentiation of glial cells into dopamine neutrons via viral vectors/ Introducing transgenes into cells into the brain
M. Airavaara and Andrii Domanskyi
37. Urso- and tauroursodeoxycholic acids as anti-apoptotic agents: Modulation of Parkinson's disease
Noha Abdelkader
38. Interlinking potential therapy with botulinum neurotoxin A and Parkinson's disease
Andreas Wree
39. Neuropeptide CART (cocaine-amphetamine-regulated transcript) and usage in Parkinson's disease
P. Mao
40. Photobiomodulation as a neuroprotective strategy for Parkinson’s disease
Daniel M. Johnstone
41. Assisted devices in Parkinson's disease
Roongroj Bhidayasiri


No. of pages:
© Academic Press 2020
7th September 2020
Academic Press
Hardcover ISBN:

About the Editors

Colin R. Martin

Dr. Martin is a Professor of Mental Health at Buckinghamshire New University. He is a Registered Nurse, Chartered Health Psychologist, and a Chartered Scientist. He has published or has in press well over 250 research papers and book chapters. He is a keen book author and editor having written and/or edited several books all of which reflect his diverse academic and clinical interests that examine in-depth, the interface between mental health and physical health. These outputs include the Handbook of Behavior; Food and Nutrition (2011), Perinatal Mental Health: A Clinical Guide (2012); Nanomedicine and the Nervous System (2012), and the major reference works Comprehensive Guide to Autism (2014), Diet and Nutrition in Dementia and Cognitive Decline (2015), Comprehensive Guide to Post-Traumatic Stress Disorder (2016) and Metabolism and Pathophysiology of Bariatric Surgery: Nutrition, Procedures, Outcomes, and Adverse Effects (2017).

Affiliations and Expertise

Professor of Perinatal Mental Health, Institute of Clinical and Applied Health Research (ICAHR), University of Hull, UK

Victor Preedy

Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRCPath, FRSC is a staff member of the Faculty of Life Sciences and Medicine within King's College London. He is also a member of the Division of Diabetes and Nutritional Sciences (research) and the Department of Nutrition and Dietetics (teaching). Professor Preedy is also Director of the Genomics Centre of King's College London. Professor Preedy graduated in 1974 with an Honours Degree in Biology and Physiology with Pharmacology. He gained his University of London PhD in 1981. In 1992, he received his Membership of the Royal College of Pathologists and in 1993 he gained his second doctorate (DSc), for his outstanding contribution to protein metabolism in health and disease. Professor Preedy was elected as a Fellow to the Institute of Biology in 1995 and to the Royal College of Pathologists in 2000. Since then he has been elected as a Fellow to the Royal Society for the Promotion of Health (2004) and The Royal Institute of Public Health (2004). In 2009, Professor Preedy became a Fellow of the Royal Society for Public Health and in 2012 a Fellow of the Royal Society of Chemistry. Professor Preedy has carried out research when attached to Imperial College London, The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with research groups in Finland, Japan, Australia, USA and Germany. Prof Preedy is a leading expert on the science of health and has a long standing interest in neurological disease and tissue pathology. He has lectured nationally and internationally. To his credit, Professor Preedy has published over 600 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and numerous books and volumes.

Affiliations and Expertise

Professor of Nutritional Biochemistry, Department of Nutrition and Dietetics, Professor of Clinical Biochemistry, Department of Clinical Biochemistry; Director of the Genomics Centre, King’s College, London, UK

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