Diagnosis and Management in Dementia
1st Edition
The Neuroscience of Dementia, Volume 1
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Description
Diagnosis and Management in Dementia: The Neuroscience of Dementia, Volume 1 consolidates different fields of dementia into a single book, covering a range of subjects, including Alzheimer’s disease, Lewy body dementia, mixed dementia, vascular dementia, physical activity, risk factors, mortality, biomarkers, SPECT, CT, MRI, questionnaires, nutrition, sleep, delirium, hearing loss, agitation, aggression, delusions, anxiety, depression, hallucinations, psychosis, senile plaques, tau and amyloid-beta, neuroinflammation, molecular biology, and more. With an impact on millions globally, and billions of research dollars being invested in dementia research, this book will stimulate research in the area and inform researchers.
Key Features
- Offers comprehensive coverage of a broad range of topics related to dementia
- Serves as a foundational collection for neuroscientists and neurologists on the biology of dementia and brain dysfunction
- Contains in each chapter an abstract, key facts, mini dictionary of terms, and summary points to aid in understanding
- Provides unique sections on specific subareas, intellectual components, and knowledge-based niches that will help readers navigate key areas for research and further clinical recommendations
- Features preclinical and clinical studies to help researchers map out key areas for research and further clinical recommendations
- Serves as a "one-stop" source for everything you need to know about dementia
Readership
Neuroscientists/neurologists, psychologists, health scientists, public health workers, research scientists, pharmacologists, and physicians. Graduate/postgraduate students, lecturers, and professors
Table of Contents
Foreword
Carolyn Roberts
Preface
I. Dementia: Introductory Chapters and Setting the Scene
1. Mixed dementia: an overview
Jaqcues J. De Reuck
2. Vascular dementia: an overview
Virginia Cipollini
3. Small vessel disease and dementia
Francesco Arba
4. Linking Amyotrophic lateral sclerosis (ALS) and Frontotemporal dementia
Philippe Couratier
5. Mortality in dementia: linking in delirium
Thiago Silva
6. Midlife diabetes and the risk of dementia- understanding the link
Sean Kennelly and Adam H. Dyer
7. Gait and Alzheimer's disease /Gait and dementia
Michele Linda Callisaya
8. Hypertension and dementia
Rebecca F. Gottesman
9. Genetics of dementia: focus on Alzheimer’s disease
Francesca Fernandez
10. Clinical and pathological phenotypes in autosomal dominant frontotemporal dementia
Innocenzo Rainero
11. Risk factors in dementia: genetic and nongenetic
Evangelos Evangelou
12. Lipidomics and biomarker in Alzheimer’s disease
Perminder S. Sachdev and UNIVERSITY OF NEW SOUTH WALES
13. The 5xFAD mouse model of Alzheimer’s disease
Sylvie Claeysen
II. Biomarkers, Psychometric Instruments And Diagnosis
14. Use of cerebrospinal fluid in diagnosis of dementia
Angelo Nuti
15. Salivary biomarkers in Alzheimer’s disease
Francesca Fernandez
16. Diacylglycerols as biomarkers in dementia
Paul Wood
17. Butyrylcholinesterase (BChE) as a biomarker in Alzheimer’s disease
Sultan Darvesh
18. Blood brain-derived neurotrophic factor as a biomarker of Alzheimers disease
Marta Balietti
19. Methods of amyloid PET Imaging and its applications to Alzheimer’s disease spectrum
Shizuo Hatashita Sr.
20. Applications of diffusion-weighted imaging (DWI) Tractography and Alzheimer’s disease
Nicola Amoroso
21. Transcranial Magnetic stimulation and diagnostic applications to dementias
Matthew Kiernan and Thanuja Dharmasada
22. Retinal imaging and dementia as a diagnostic tool
Carol Y. Cheung
23. The prediction of Alzheimer’s disease
Athanasios Alexiou
24. Addenbrooke's Cognitive Examination
Jordi A. Matias-Guiu
25. The Montreal Cognitive Assessment (MoCA) and applications to dementia
Andrea Bosco
26. ALBA Screening Instrument (ASI) and applications to dementia
Angel Golimstok
27. The Quick Mild Cognitive Impairment (Qmci) screen and applications to dementia
Roger Clarnette
28. Assessment of activities of daily living (ADL) applied to dementia
Patricia De Vriendt
III. Pharmacological Treatments For Dementia
29. Cholinesterase inhibitors in dementias: an overview
Patrizia Mecocci
30. Choline-containing phospholipids and treatment of adult-onset dementia disorders
Francesco Amenta
31. Donepezil usage: a focused review
Francesco Amenta
32. Memantine: a focused review
Sergio del Rio Sancho
33. The benefits of calcium channel blockers for the therapy of dementia
L. Bergantin
34. Pitfalls for pharmacotherapeutic trials in dementia
T. Mueller
35. All-trans retinoic acid in Alzheimer’s disease
Siamak Beheshti
36. Dementias and usage of NMDA receptor antagonists
Brianna E. Glynn-Servedio
37. Dementia and bladder dysfunction: a focus on treatments with anticholinergics
Ryuji Sakakibara
38. Linking astrocytes' exosomes to Alzheimer's pathogenesis and therapy
Anna Chiarini
39. Changing the fate: therapeutic mechanisms focus on the switch of beta-amyloid precursor protein (APP) processing
Kristina Endres
40. Acetylcholinesterase inhibitory agents in plants and application to dementia: Alzheimers Disease
Willian Orlando Castillo-Ordonez
41. Removal of blood amyloid as a safety strategy
Nobuya Kitaguchi
IV. Non-Pharmacological Treatments and Procedures
42. Caring for people with Dementia in the Acute Hospital
R. Briggs and Sean Kennelly
43. Environmental enrichment in dementia
Kimberley Stuart
44. Music therapy in dementia
Alfredo Raglio and Lapo Attardo
45. Aromatherapy in dementia
G. Bagetta and Damiana Scuteri
46. Dancing in dementia
Lee-Fay Low and Kathryn Dovey
47. Hypoxic-hyperoxic training and dementia
Martin Burtscher
48. Linking amyloid and depression in dementia: effects of treatments by non-drug means
Akihiko Nunomura
49. Regional dementia care networks
Franziska laporte Uribe
50. Cognitive behavioural therapy (CBT) use in Alzheimer’s disease
Alicia Ann Walf
51. Maximizing cognition in Mild Cognitive Impairment and early-stage dementia
Bridget Regan
52. Exercise, cognitive creativity, and dementia
Paul D. Loprinzi
53. Linking care staff, person-focused communications and dementias
Marie Y. Savundranayagam
Details
- No. of pages:
- 835
- Language:
- English
- Copyright:
- © Academic Press 2020
- Published:
- 1st August 2020
- Imprint:
- Academic Press
- Hardcover ISBN:
- 9780128158548
About the Editors
Colin R. Martin
Dr. Martin is a Professor of Mental Health at Buckinghamshire New University. He is a Registered Nurse, Chartered Health Psychologist, and a Chartered Scientist. He has published or has in press well over 250 research papers and book chapters. He is a keen book author and editor having written and/or edited several books all of which reflect his diverse academic and clinical interests that examine in-depth, the interface between mental health and physical health. These outputs include the Handbook of Behavior; Food and Nutrition (2011), Perinatal Mental Health: A Clinical Guide (2012); Nanomedicine and the Nervous System (2012), and the major reference works Comprehensive Guide to Autism (2014), Diet and Nutrition in Dementia and Cognitive Decline (2015), Comprehensive Guide to Post-Traumatic Stress Disorder (2016) and Metabolism and Pathophysiology of Bariatric Surgery: Nutrition, Procedures, Outcomes, and Adverse Effects (2017).
Affiliations and Expertise
Professor of Perinatal Mental Health, Institute of Clinical and Applied Health Research (ICAHR), University of Hull, UK
Victor Preedy
Victor R. Preedy BSc, PhD, DSc, FRSB, FRSPH, FRCPath, FRSC is a staff member of the Faculty of Life Sciences and Medicine within King's College London. He is also a member of the Division of Diabetes and Nutritional Sciences (research) and the Department of Nutrition and Dietetics (teaching). Professor Preedy is also Director of the Genomics Centre of King's College London. Professor Preedy graduated in 1974 with an Honours Degree in Biology and Physiology with Pharmacology. He gained his University of London PhD in 1981. In 1992, he received his Membership of the Royal College of Pathologists and in 1993 he gained his second doctorate (DSc), for his outstanding contribution to protein metabolism in health and disease. Professor Preedy was elected as a Fellow to the Institute of Biology in 1995 and to the Royal College of Pathologists in 2000. Since then he has been elected as a Fellow to the Royal Society for the Promotion of Health (2004) and The Royal Institute of Public Health (2004). In 2009, Professor Preedy became a Fellow of the Royal Society for Public Health and in 2012 a Fellow of the Royal Society of Chemistry. Professor Preedy has carried out research when attached to Imperial College London, The School of Pharmacy (now part of University College London) and the MRC Centre at Northwick Park Hospital. He has collaborated with research groups in Finland, Japan, Australia, USA and Germany. Prof Preedy is a leading expert on the science of health and has a long standing interest in neurological disease and tissue pathology. He has lectured nationally and internationally. To his credit, Professor Preedy has published over 600 articles, which includes peer-reviewed manuscripts based on original research, abstracts and symposium presentations, reviews and numerous books and volumes.
Affiliations and Expertise
Professor of Nutritional Biochemistry, Department of Nutrition and Dietetics, Professor of Clinical Biochemistry, Department of Clinical Biochemistry; Director of the Genomics Centre, King’s College, London, UK
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