Oxidative Stress and Dietary Antioxidants

2nd Edition - April 16, 2020

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  • Editor: Victor Preedy
  • Paperback ISBN: 9780128157763
  • eBook ISBN: 9780128157770

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Diabetes: Oxidative Stress and Dietary Antioxidants, Second Edition, builds on the success of the first edition, covering updated research on the science of oxidative stress in diabetes and the potentially therapeutic usage of natural antioxidants in the diet and food matrix. The processes within the science of oxidative stress are not described in isolation, but rather in concert with other processes, such as apoptosis, cell signaling and receptor mediated responses. This approach recognizes that diseases are often multifactorial and oxidative stress is a single component of this. Since the publication of the first edition, the science of oxidative stress and free radical biology continues to rapidly advance with thousands of the research articles on the topic. New sections in this update cover the role of dietary advanced glycation end products (AGEs) in causing OS in diabetes, oxidative stress and diabetes-induced bone metabolism, and oxidative stress and diabetic foot ulcer.

Key Features

  • Saves clinicians and researchers time in quickly accessing the very latest details on a broad range of diabetes and oxidation issues
  • Combines the science of oxidative stress and the putative therapeutic usage of natural antioxidants in the diet, its food matrix or plant
  • Includes preclinical, clinical and population studies to help endocrinologists, diabetologists, nutritionists, dieticians and clinicians map out key areas for research and further clinical recommendations


Diabetologists, endocrinologists, nutritionists, dietitians, food scientists, physicians and clinical workers, health care workers and research scientists

Table of Contents

  • 1. Oxidative Stress and Diabetes
    2. Sources of free radicals in diabetes
    3. Oxidative stress and autophagy in diabetes
    4. Exosomes and oxidative stress Linking insulin, oxidative stress and mitochondria (author to be aware of overlap with Mitochondrial oxidative stress in diabetes Prof. V. M. Victor)
    5. Diabetes, peroxisomes and reactive radical species
    6. NADPH oxidase and oxidative stress: implications for diabetes
    7. Linking xanthine oxidase and free radicals in diabetic condition
    8. Linking arachidonic acid metabolism and oxidative stress: implications for diabetes
    9. Linking cytochome P450s, oxidative stress and diabetes
    10. Linking heme metabolism, oxidative stress and diabetes
    microRNAs in linking reactive species and diabetes (where possible author to add other small RNAs to the review)
    11. Mitochondrial oxidative stress in diabetes
    12. Oxidative stress, diabetes and iron
    13. Oxidative stress and diabetic neuropathy
    14. Diabetic stroke and oxidative stress
    15. Diabetic cardiomyopathy and oxidative stress
    16. Oxidative stress in diabetic retinopathy
    17. Bone, diabetes and oxidative stress
    18. Linking insulin, advanced glycation end products and oxidative stress
    19. Metformin, oxidative stress and diabetes
    20. SGLT2 inhibitors, diabetes and oxidative stress
    21. Antioxidants and Diabetes
    22. Effect of Red sage (salvia miltiorrhiza) on antioxidant enzymes in diabetic patients
    23. Antioxidant spices and herbs and use in diabetes
    24. Resveratrol and oxidative stress in diabetes
    25. Vitamin D, oxidative stress and diabetes
    26. Glutamine and antioxidant potential in diabetes
    27. Herbal Chrysanthemi Flos, oxidative damage and diabetic vascular protection
    28. Polyphenols, oxidative stress and vascular damage in diabetes
    29. Alpha-tocopherol supplementation, lipid profile and insulin sensitivity in diabetes
    30. Vitamin E and vascular protection in diabetes
    31. Carotenoids, diabetes and oxidative balance (This must be an original review)
    32. Ginkgo biloba, oxidative stress, atherosclerosis protection in diabetes
    33. Taurine and cardiac oxidative stress in diabetes
    34. Statins, diabetic oxidative stress and vascular tissue
    35. Anti-oxidative component of docosahexaenoic acid (DHA) in the brain in diabetes
    36. Resveratrol and cerebral arterioles in type 1 diabetes
    37. Antioxidant supplements and diabetic retinopathy
    38. Neuroprotective lutein in the retina and oxidative stress
    39. Anti-oxidant related micronutrients and diabetic retinopathy
    40. Pomegranate juice, oxidative stress and the lung in diabetes
    41. Antioxidants, Oxidative stress and Pre-eclampsia in Type 1 diabetes
    42. Zinc supplementation, diabetic foot and antioxidant capacity
    43. Assays and techniques
    44. Methods for assaying selenium proteins and metabolites
    45. Assessing the antioxidant activities of plants
    46. Liquid chromatography-electrospray ionization-tandem mass spectrometry and applications to antioxidant biodiscovery
    47. Measurement of Intracellular reactive oxygen species and application
    48. Methods for assaying biomarkers of oxidative stress in in vivo studies and applications to diabetes
    49. Methods for extracting antioxidants from plants
    50. Measurement of Intracellular reactive oxygen species and application Biomarkers of lipid peroxidation
    51. Battery tests: DPPH, FRAP and ABTS assays and applications to diabetes
    52. Battery tests: Radical-scavenging activity, superoxide radical-scavenging and hydroxyl radical-scavenging assays

Product details

  • No. of pages: 454
  • Language: English
  • Copyright: © Academic Press 2020
  • Published: April 16, 2020
  • Imprint: Academic Press
  • Paperback ISBN: 9780128157763
  • eBook ISBN: 9780128157770

About the Editor

Victor Preedy

Dr. Preedy is a senior member of King's College London and Director of the Genomics Centre and a member of the Faculty of Life Sciences and Medicine. Professor Preedy has longstanding academic interests in substance misuse especially in relation to health and well-being. In his career Professor Preedy was Reader at the Addictive Behaviour Centre at The University of Roehampton, and also Reader at the School of Pharmacy (now part of University College London; UCL). Professor Preedy is an extremely experienced book editor, having edited influential works including but not limited to The Handbook of Alcohol Related Pathology, The Neuropathology of Drug Addictions and Substance Misuse, The Handbook of Cannabis and Related Pathologies, The Neuroscience of Cocaine, and upcoming titles The Neuroscience of Alcohol, The Neuroscience of Nicotine, and more (all Elsevier).

Affiliations and Expertise

Professor of Nutritional Biochemistry, Department of Nutrition and Dietetics, Professor of Clinical Biochemistry, Department of Clinical Biochemistry; Director of the Genomics Centre, King’s College, London, UK

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  • امير Mon May 11 2020