Developmental Biology and Musculoskeletal Tissue Engineering - 1st Edition - ISBN: 9780128114674

Developmental Biology and Musculoskeletal Tissue Engineering

1st Edition

Principles and Applications

Editors: Girish Pattappa April Craft Oliver Gardner Martin Stoddart
Paperback ISBN: 9780128114674
Imprint: Academic Press
Published Date: 1st June 2018
Page Count: 300
Tax/VAT will be calculated at check-out Price includes VAT (GST)

Institutional Access

Secure Checkout

Personal information is secured with SSL technology.

Free Shipping

Free global shipping
No minimum order.

Description

Developmental Biology and Musculoskeletal Tissue Engineering: Principles and Applications focuses on the regeneration of orthopedic tissue, drawing upon expertise from developmental biologists specializing in orthopedic tissues and tissue engineers who have used and applied developmental biology approaches. Musculoskeletal tissues have an inherently poor repair capacity, and thus biologically-based treatments that can recapitulate the native tissue properties are desirable. Cell- and tissue-based therapies are gaining ground, but basic principles still need to be addressed to ensure successful development of clinical treatments. Written as a source of information for practitioners and those with a nascent interest, it provides background information and state-of-the-art solutions and technologies.

Recent developments in orthopedic tissue engineering have sought to recapitulate developmental processes for tissue repair and regeneration, and such developmental-biology based approaches are also likely to be extremely amenable for use with more primitive stem cells.

Key Features

  • Brings the fields of tissue engineering and developmental biology together to explore the potential for regenerative research
  • Provides an outline of the development of the musculoskeletal system in general
  • Addresses the effect of mechanical forces on the musculoskeletal system during its development
  • Discusses the importance of genes for the development of musculoskeletal tissues and their potential use in tissue engineering
  • Describes how developmental biology is being used to influence and guide tissue engineering approaches for cartilage, bone, Meniscus, disc, tendon and muscle repair

Readership

TE and developmental biology researches, post-docs and grad students; clinicians in the field of orthopaedics and tissue transplantation

Table of Contents

  1. Developmental biology of musculoskeletal tissues for Tissue Engineers
    2. The Mechanics of Musculoskeletal Development
    3. HOX genes in musculoskeletal development
    4. Developmental and orthopaedic diseases
    5. Synovial joint development
    6. Articular and Growth plate Cartilage development
    7. Bone development
    8. Meniscus development
    9. Disc development
    10. Tendon development
    11. Muscle development
    12. Biomimetic tissue engineering based on human development
    13. Clinical translation

Details

No. of pages:
300
Language:
English
Copyright:
© Academic Press 2018
Published:
Imprint:
Academic Press
Paperback ISBN:
9780128114674

About the Editor

Girish Pattappa

Senior Postdoctoral Fellow and Faculty of Dental Surgery Centre for Osteoarticular and dental tissue engineering, University of Nantes, France Co-Chair, TERMIS 2015 workshop, “The Tissue Engineering-Developmental Biology Paradigm – A Tool for Developing Successful Therapies”

Affiliations and Expertise

Department of Trauma Surgery, Regensburg University Medical Center, Regensburg, Germany

April Craft

Assistant Professor and Affiliate Faculty Member, Orthopaedic Surgery, Stem Cells and Regenerative Biology, Harvard University Assistant Professor, Department of Orthopaedic Surgery, Boston Children's Hospital Principal Faculty, Harvard Stem Cell Institute

Affiliations and Expertise

Boston Children's Hospital, Orthopaedic Research, Boston, MA, USA

Oliver Gardner

Post-doctoral research fellow, Orthopaedic Surgery, Boston Children's Hospital, Harvard Medical School and Harvard Department of Stem Cell and Regenerative Biology, Harvard University Co-Chair, TERMIS 2015 workshop, “The Tissue Engineering-Developmental Biology Paradigm – A Tool for Developing Successful Therapies”

Affiliations and Expertise

Orthopaedic Surgery, Boston Children's Hospital, Harvard Medical School and Harvard Department of Stem Cell and Regenerative Biology, Harvard University, Boston, MA, USA

Martin Stoddart

Principal Scientist, AO Research Institute, Stem Cell Focus Area Leader, Musculoskeletal Regeneration Program Honorary Professor, Institute for Science and Technology in Medicine, University of Keele, UK Honorary Professor, Medical Faculty, Albert Ludwigs University of Freiburg, Germany Fellow of the Royal Society of Biology (FRSB) Editorial Board Member, Journal of Functional Morphology and Kinesiology, Tissue Engineering, Biomed Research International Orthopeadics, Frontiers in Craniofacial Biology. Scientific Editor, European Cells and Materials Journal Associate Faculty Member, Faculty of 1000 Medicine

Affiliations and Expertise

AO Research Institute Davos, Davos, Switzerland