Developmental Aspects of the Cell Cycle

Developmental Aspects of the Cell Cycle

1st Edition - January 1, 1971

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  • Editor: Ivan Cameron
  • eBook ISBN: 9780323152099

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Description

Developmental Aspects of the Cell Cycle discusses the molecular, organelle, cellular, and organismal levels of cell cycle, cell proliferation, and cell differentiation. It addresses the possible antagonism between the ability of cells to proliferate and to differentiate. After brief historical, theoretical, and methodological background information for each cell system, this book concentrates on the mechanisms involved in the regulation of cell proliferation and differentiation. The book presents systems in which mass cultures of cells can be induced to undergo a synchronous transition from one cell state to another, enabling the amplification of cellular and biochemical events to be analyzed with the available morphological and biochemical techniques. Some chapters explain the possibility of cell state production by a microenvironment that occurs at the organismal level, in which a series of mitotic and growth steps causes cells proliferation. The concluding chapters discuss cell proliferation and differentiation in specific cell system, such as embryonic chick and male germ cell. This book will appeal to investigators in many disciplines, teachers, and life sciences students, particularly, to molecular, cellular, and developmental biologists.

Table of Contents


  • List of Contributors

    Preface

    1. The Cell Cycle and Cell Differentiation in Trypanosomatids

    I. Introduction

    II. Life Cycles and Cell Differentiation

    III. Cell Cycles and Differentiation

    References

    2. Characteristics of Macronuclear RNA in the Cell Cycle of Synchronized Tetrahymena

    I. Introduction

    II. Nucleocytoplasmic Interactions

    III. Stomatogenesis and Polyribosomal Assembly

    IV. Nucleic Acid Synthesis

    V. Summary and Concluding Remarks

    References

    3. Cell Transformation Studies on the Amoeba-Flagellate, Naegleria gruberi

    I. Introduction

    II. Historical Aspects

    III. Modern Studies

    IV. Concluding Remarks

    References

    4. Temporal Patterns in the Ciliated Protozoa

    I. The Nature of Temporal Events

    II. Maturity Patterns in Tetrahymena

    III. Mechanisms of Temporal Control

    IV. Concluding Remarks

    References

    5. Mitosis and Differentiation in Hydra Morphogenesis

    I. Introduction

    II. Structural Aspects

    III. Selection of Experimental Hydra

    IV. Techniques for Analyzing Mitosis in Hydra

    V. Effects of Mitotic Inhibitors on Regeneration and Morphogenesis

    VI. Concluding Remarks

    References

    6. Radiation Responses during the Mitotic Cycle of the Sea Urchin Egg

    I. Introduction

    II. General Effects of Irradiating Gametes or Zygotes

    III. Effects on Sperm

    IV. Effects on Unfertilized Eggs

    V. Cyclical Changes

    VI. Questions Concerning Targets

    VII. General Conclusions and Considerations for the Future

    References

    7. Cell Division and Transcription in Developing Frog Embryos

    I. Relation of Cell Division to Differentiation

    II. RNA Synthesis in Developing Frog Embryos

    III. Relation of Transcription to Time of DNA Replication

    IV. Effect of Rate and Number of Divisions on Transcription

    V. Summary

    References

    8. Relationship between Cell Proliferation and Cytodifferentiation in Embryonic Chick Tissues

    I. Introduction

    II. Review of Individual Developing Systems

    III. Discussions and Conclusions

    References

    9. Studies on Cellular Proliferation and Chondrogenesis

    I. Introduction

    II. Cell Cycle and Chondrogenesis

    III. Discussion

    IV. Summary

    References

    10. Differentiation of the Male Germ Cell

    I. Introduction

    II. The Cycle of the Seminiferous Epithelium

    III. Gametogenesis

    IV. Final Stages of Spermatozoan Differentiation—The Female Reproductive Tract

    References

    11. Immunoglobulin Production in Proliferating Lymphoid Cells

    I. Introduction

    II. Immunoglobulin Synthesis in Relation to Culture Dynamics

    III. Immunoglobulin Gene Expression during the Cell Cycle

    IV. Discussion

    V. Summary

    References

    12. Initial Stages of Cellular Differentiation in the Blood-Forming System of the Mouse

    I. Introduction

    II. Cellular Organization in the Hemopoietic System

    III. Regulation of Stem Cell Functions

    IV. Summary

    References

    13. Hormonal Regulation of Cell Proliferation and Differentiation

    I. Introduction

    II. Hormonal Regulation of Cell Proliferation

    III. Hormone-Dependent Cell Differentiation

    IV. Relationship of Proliferation to Differentiation

    V. Some Possible Mechanisms in Hormonal Regulation of Gene Expression

    VI. Summary

    References

    Author Index

    Subject Index






Product details

  • No. of pages: 400
  • Language: English
  • Copyright: © Academic Press 1971
  • Published: January 1, 1971
  • Imprint: Academic Press
  • eBook ISBN: 9780323152099

About the Editor

Ivan Cameron

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