Description

The nervous system is highly complex both in its structural order and in its ability to perform the many functions required for survival and interaction with the environment; understanding how it develops has proven to be one of the greatest challenges in biology. Such precision demands that key events at every developmental stage are executed properly and are coordinated to produce the circuitry underlying each of the adult nervous system's functions. This volume describes the latest research on the cellular and molecular mechanisms of neural circuitry development, while providing researchers with a one-stop overview and synthesis of contemporary thought in the area.

Key Features

Reviews current research findings on the development of neural circuitry, providing researchers with an overview and synthesis of the latest contemporary thought in the cellular and molecular mechanisms that underlie the development of neural circuitry Includes chapters discussing topics such as the guidance of nerve growth and the formation of plasticity of synapses, helping researchers better understand underlying mechanisms of neural circuit development and maintenance that may play a role in such human diseases/conditions as depression, anxiety, and pain Chapters make use of a variety of human and animal models, allowing researchers to compare and contrast neural circuitry development across a wide spectrum of models

Readership

Researchers and students of cell, developmental, and molecular biology as well as genetics.

Table of Contents

1. Takao Hensch 2. The developmental genetic influences on cortical interneuron connectivity and diversity (Gord Fishell) 3. Development of neural circuits in the fly ventral nervous system (Marta Zlatic and Wesley Grueber) 4. Regulating synapse formation in developing neural circuits (Daniel Colon-Ramos) 5. Development of the C.elegans motor circuit (David Miller) 6. Anterograde and retrograde signals in fly visual system development (Sam Kunes) 7. Anterograde and retrograde signals in fly visual system development (Peter Scheiffele) 8. Development of neural circuits in the vertebrate spinal cord (Jeremy Dasesn) 9. Development of neural circuits in the Adult Hippocampus (Fred Gage, Yan Li and Yangling Mu) 10. Theoretical models of neural circuit development (Geoffrey Goodhill) 11. Maintenance of neuronal circuit structure (Claire Benard & Oliver Hobert)

Details

No. of pages:
240
Language:
English
Copyright:
© 2009
Published:
Imprint:
Academic Press
Print ISBN:
9780123744692
Electronic ISBN:
9780080922614