Description

Thanks to advances in genetics and genomics, research on inner ear development has flourished. Better approaches and experimental models have shed light on the function of a variety of vertebrate genes and their related proteins. This latest volume of Current Topics in Developmental Biology delves into this new research to show how the discovery of more genes involved in the development of the inner ear leads to the generation of new models that examine a wealth of issues -- from the origins of human deafness to the roles of genes during inner ear induction, development and differentiation. The wide variety of experimental approaches will help readers to understand the broad range of issues related to inner ear morphogenesis and other concepts from complementary areas of investigation. This state-of-the-art overview will be essential reading for researchers, clinicians and students alike.

Key Features

* Scores of high-quality, full- color figures * Detailed schemes on the structure and timing of ear development * Current Topics in Developmental Biology is the longest-running forum for contemporary issues in developmental biology

Readership

Undergraduate and graduate students in biology, developmental biology, neuroscience, audiology and hearing sciences, university teachers as well as specialized medical professional such as otologists and specialists in certain areas of hearing sciences.

Table of Contents

Reviews include: Molecular conservation and novelties in vertebrate ear development Formation of the outer and middle ear, molecular mechanisms Molecular basis of inner ear induction FGF signaling in ear development and innervation The roles of retinoic acid during inner ear development Growth factors and early development of otic neurons

Details

No. of pages:
490
Language:
English
Copyright:
© 2003
Published:
Imprint:
Academic Press
Print ISBN:
9780121531577
Electronic ISBN:
9780080490915

About the editors

Raymond Romand

Affiliations and Expertise

Institut de Clinique de la Souris and Institut de Biologie Moléculaire et Cellulaire Illkirch, France

Isabel Varela-Nieto

Affiliations and Expertise

Instituto de Investigaciones Biomédicas "Alberto Sols," CSIC-UAM, Madrid, Spain