Development, Differentiation and Disease of the Para-Alimentary Tract

Development, Differentiation and Disease of the Para-Alimentary Tract

1st Edition - November 29, 2010

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  • Editor: Klaus Kaestner
  • Hardcover ISBN: 9780123852335
  • eBook ISBN: 9780123852342

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Understanding how digestive organs develop, their physiology and structure is important for determining new therapies to combat diseases of the digestive organs. This volume reviews the latest research and developments in this field.

Key Features

  • Discusses new discoveries, approaches, and ideas
  • Contributions from leading scholars and industry experts
  • Reference guide for researchers involved in molecular biology and related fields


Researchers, professors and graduate students in biochemistry, chemistry, molecular biology, biotechnology, and medicine

Table of Contents

  • 1. Transcriptional Control of Acinar Development and Homeostasis
    Raymond J. MacDonald, Galvin H. Swift, and Francisco X. Real
    2. Molecular Biology of Pancreatic Ductal Adenocarcinoma Progression:Aberrant Activation of Developmental Pathways
    Andrew D. Rhim and Ben Z. Stanger
    3. Transcriptional Control of Hepatocyte Differentiation
    Masato Nagaoka and Stephen A. Duncan
    4. Molecular Mechanisms of Biliary Development
    Frédéric P. Lemaigre
    5. Molecular determinants of liver zonation
    Cyril Torre, Christine Perret, and Sabine Colnot
    6. Fibrosis in the Liver: acute protection and chronic disease
    Youngmin Lee and Scott L. Friedman
    7. Hierarchies of transcriptional regulation during liver regeneration
    Svitlana Kurinna and Michelle Craig Barton
    8. Biology of the Adult Hepatic Progenitor Cell: "Ghosts in the Machine"
    Houda Darwiche and Bryon E. Petersen
    9. Signaling networks in human hepatocarcinogenesis - novel aspects and therapeutic options
    K. Breuhahn, P. Schirmacher

Product details

  • No. of pages: 304
  • Language: English
  • Copyright: © Academic Press 2010
  • Published: November 29, 2010
  • Imprint: Academic Press
  • Hardcover ISBN: 9780123852335
  • eBook ISBN: 9780123852342

About the Serial Volume Editor

Klaus Kaestner

Affiliations and Expertise

Institute of Diabetes, Obesity & Metabolism, University of Pennsylvania School of Medicine, PA, USA

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