Detection Methods for Cynobacterial toxins

1st Edition

Editors: G A Codd T M Jefferies C W Keevil E Potter
Hardcover ISBN: 9781855738027
eBook ISBN: 9781845698164
Imprint: Woodhead Publishing
Published Date: 1st January 1994
Page Count: 202
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Description

Cyanobacteria, or blue-green algae, commonly occur in a variety of water types throughout the world. A variable, but, high proportion of the cyanobacterial blooms and scums, which can develop annually in lakes, reservoirs, canals and slow-flowing rivers, contain potent toxins. Although animal poisonings and human health problems associated with the ingestion of, or contact with, cyanobacterial scums have long been recognized, a developing understanding of the health hazards posed by the toxins requires that reliable, sensitive, specific and convenient methods are available for their detection and quantification.

Detection methods for cynobacterial toxins looks at the application of biological, toxicological, biochemical and physicochemical techniques in studies of cyanobacterial toxins and at experimental methods that have identified at least 50 cyanobacterial compounds toxic to vertebrates.

Academics, public health bodies, environmental protection agencies and water companies are all involved in monitoring cyanobacterial levels and effects, and this book will help to ensure that their research is not duplicated, is standardized and comparable, and that optimal progress can be made in an important area that is still in its developing stages.

Readership

Academics, public health bodies, environmental protection agencies, and water companies

Table of Contents

Health problems from exposure to cyanobacteria and proposed safety guidelines for drinking and recreational water; An epidemiological critique of reports of human illness associated with cyanohacteria; Cyclic peptide hepatotoxins from fresh water cyanobacteria water blooms collected in the river dnieper reservoirs and other water bodies from the European part of Russia; Structural analysis of cyanobacterial toxins; Determinations of anatoxin-a, homoanatoxin and propylanatoxin in cyanobacterial extracts by HPLC, GC-mass spectrometry and capillary electrophoresis; Enantiomer-specific analysis of homoanatoxin-a. a cyanophyte neurotoxin; Neurotoxins from Australian Anabaena; The analysis of microcystin-LR in water: Application in water treatment studies; The analysis of microcystins in raw and treated water; Application of HPLC and mass spectrometry (MALDI) to the detection and identification of toxins from microcystis, oscillatoria and aphanizomenon from several freshwater reservoirs; Routes of intoxication; Testing of toxicity in cyanobacteria by cellular assays; A sensitive bioscreen for detection of cyclic peptide toxins of the microcystin class; The inhibition of protein phosphatases by toxins: Implications for health and an extremely sensitive and rapid bioassay for toxin detection; Detection of hepatotoxins by protein phosphatase inhibition assay: advantages, pitfalls and anomalies; Alternatives to the mouse bioassay for cyanobacterial toxicity assessment; Evaluation of assay methods for the determination of cyanobacterial hepatotoxicity; The role of synthetic chemistry in the production of standards for toxin analysis; Sources of uncertainty in assessing the health risk of cyanobacterial blooms in drinking water supplies; Standing committee of analysts; Toxic cyanobacteria (blue-green algae) in Portuguese freshwaters; Screening of cyanobactenal toxins in microcystis aeruginosa collected from blooms and cultures; Toxicity studies with blue-green algae from Flemis

Details

No. of pages:
202
Language:
English
Copyright:
© Woodhead Publishing 1994
Published:
Imprint:
Woodhead Publishing
eBook ISBN:
9781845698164
Hardcover ISBN:
9781855738027

About the Editor

G A Codd

Affiliations and Expertise

University of Dundee

T M Jefferies

Affiliations and Expertise

University of Bath

C W Keevil

Affiliations and Expertise

Centre for Applied Microbiology and Research

E Potter

Affiliations and Expertise

National Rivers Authority, UK