Desk Encyclopedia of General Virology - 1st Edition - ISBN: 9780123751461, 9780123751621

Desk Encyclopedia of General Virology

1st Edition

Editors: Marc van Regenmortel Brian Mahy
Hardcover ISBN: 9780123751461
eBook ISBN: 9780123751621
Imprint: Academic Press
Published Date: 2nd September 2009
Page Count: 672
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Description

Section 1. GENERAL TOPICS
History of virology : bacteriophages
History of virology :  plant viruses
History of virology : vertebrate viruses
Nature of viruses
Origin of viruses
Ribozymes
Virus species
Quasispecies
Virus databases
Phylogeny of viruses
Evolution of viruses
Taxonomy, classification and nomenclature of viruses
Virus classification by pairwise sequence comparison
Prions of vertebrates
Viruses and bioterrorism

Section 2. VIRIONS  
Principles of virion structure
Structure of non-enveloped virions
Electron microscopy of viruses
Cryo-electron microcopy
Assembly of non-enveloped virions
Assembly of enveloped virions
Assembly of bacterial viruses
Genome packaging of bacterial viruses
Viral membranes
Mimivirus

Section 3. NUCLEIC ACIDS 
Recombination
Satellite nucleic acids and viruses
Retrotransposons of vertebrates
Defective interfering viruses
Interfering RNAs
Viruses as vectors in gene therapy 

Section 4. VIRUS INFECTION 
Viral receptors 
Virus entry to bacterial cells
Membrane  fusion
Replication of viruses
Persistent and latent viral infection
Apoptosis and virus infection
Viral pathogenesis
Antiviral agents
Diagnosis using serological and molecular approaches
Diagnosis using microarrays
Disease surveillance

Section 5. IMMUNE RESPONSES
Innate immunity
Defeating innate immunity
Antigen presentation
Antigenicity and immunogenicity  of viral proteins
Cytokines and chemokines
Cell-mediated immunity to viruses
Antibody - mediated immunity to viruses
Orthomyxovirus antigen structure
Antigenic variation
Vaccine strategies
DNA Vaccines
Vaccine safety
Neutralization of infectivity
Immunopathology

Section 6. DESCRIPTION AND MOLECULAR BIOLOGY OF SOME VIRUSES
Adenoviruses : molecular biology
Baculoviruses : molecular biology of granuloviruses
Baculoviruses : molecular biology of nucleopolyhedroviruses
Coronaviruses : molecular biology
Hepatitis virus B : molecular biology
Herpes simplex viruses : molecular biology
Human cytomegalovirus : molecular biology
Human immunodeficiency viruses : molecular biology
Iridoviruses
Kaposi’s sarcoma-associated herpesvirus : molecular biology
Mononegavirales
Nidovirales
Nodaviruses
Orthomyxoviruses : molecular biology
Papillomaviruses  : molecular biology
Partitiviruses
Phycodnaviruses
Picornaviruses
Reoviruses  : molecular biology
Seadornaviruses
Tetraviruses
Togaviruses : molecular biology

Key Features

  • The most comprehensive single-volume source providing an overview of virology to non-specialists
  • Bridges the gap between basic undergraduate texts and specialized reviews
  • Concise and general overviews of important topics within the field will help when preparing for lectures, writing reports, or drafting grant applications
  • Readership

    virologists, microbiologists, immunologists, parasitologists working in research, teaching, industry and government

    Table of Contents

    Section 1. GENERAL TOPICS
    History of virology : bacteriophages
    History of virology :  plant viruses
    History of virology : vertebrate viruses
    Nature of viruses
    Origin of viruses
    Ribozymes
    Virus species
    Quasispecies
    Virus databases
    Phylogeny of viruses
    Evolution of viruses
    Taxonomy, classification and nomenclature of viruses
    Virus classification by pairwise sequence comparison
    Prions of vertebrates
    Viruses and bioterrorism

    Section 2. VIRIONS  
    Principles of virion structure
    Structure of non-enveloped virions
    Electron microscopy of viruses
    Cryo-electron microcopy
    Assembly of non-enveloped virions
    Assembly of enveloped virions
    Assembly of bacterial viruses
    Genome packaging of bacterial viruses
    Viral membranes
    Mimivirus

    Section 3. NUCLEIC ACIDS 
    Recombination
    Satellite nucleic acids and viruses
    Retrotransposons of vertebrates
    Defective interfering viruses
    Interfering RNAs
    Viruses as vectors in gene therapy 

    Section 4. VIRUS INFECTION 
    Viral receptors 
    Virus entry to bacterial cells
    Membrane  fusion
    Replication of viruses
    Persistent and latent viral infection
    Apoptosis and virus infection
    Viral pathogenesis
    Antiviral agents
    Diagnosis using serological and molecular approaches
    Diagnosis using microarrays
    Disease surveillance

    Section 5. IMMUNE RESPONSES
    Innate immunity
    Defeating innate immunity
    Antigen presentation
    Antigenicity and immunogenicity  of viral proteins
    Cytokines and chemokines
    Cell-mediated immunity to viruses
    Antibody - mediated immunity to viruses
    Orthomyxovirus antigen structure
    Antigenic variation
    Vaccine strategies
    DNA Vaccines
    Vaccine safety
    Neutralization of infectivity
    Immunopathology

    Section 6. DESCRIPTION AND MOLECULAR BIOLOGY OF SOME VIRUSES
    Adenoviruses : molecular biology
    Baculoviruses : molecular biology of granuloviruses
    Baculoviruses : molecular biology of nucleopolyhedroviruses
    Coronaviruses : molecular biology
    Hepatitis virus B : molecular biology
    Herpes simplex viruses : molecular biology
    Human cytomegalovirus : molecular biology
    Human immunodeficiency viruses : molecular biology
    Iridoviruses
    Kaposi’s sarcoma-associated herpesvirus : molecular biology
    Mononegavirales
    Nidovirales
    Nodaviruses
    Orthomyxoviruses : molecular biology
    Papillomaviruses  : molecular biology
    Partitiviruses
    Phycodnaviruses
    Picornaviruses
    Reoviruses  : molecular biology
    Seadornaviruses
    Tetraviruses
    Togaviruses : molecular biology

    Details

    No. of pages:
    672
    Language:
    English
    Copyright:
    © Academic Press 2010
    Published:
    Imprint:
    Academic Press
    eBook ISBN:
    9780123751621
    Hardcover ISBN:
    9780123751461

    About the Editor

    Marc van Regenmortel

    Affiliations and Expertise

    ESBS , CNRS , Strasbourg, France

    Brian Mahy

    Affiliations and Expertise

    Coordinating Center for Infectious Diseases, CDC, Atlanta, GA, USA