Design of Nanostructures for Theranostics Applications

Design of Nanostructures for Theranostics Applications

1st Edition - November 30, 2017

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  • Editor: Alexandru Grumezescu
  • eBook ISBN: 9780128136706
  • Paperback ISBN: 9780128136690

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Design of Nanostructures for Theranostics Applications focuses on the theranostics applications of nanostructures. In particular, multifunctional nanoparticles for diagnostics and treatment of different diseases, including those relating to the blood-brain barrier, are discussed in detail. Chapters explore different type of nanostructures, covering design, fabrication, functionalization and optimization, helping readers obtain the desired properties. Written by a diverse range of international academics, this book is a valuable reference resource for those working in both nanoscience and the pharmaceutical industry.

Key Features

  • Explores how the design of a range of nanomaterials make them effective theranostic agents, including multifunctional core-shell nanostructures, mesoporous silica nanoparticles, and quantum dots
  • Shows how nanomaterials are used effectively for a range of diseases, including breast cancer, prostate cancer and neurological disorders
  • Assesses the pros and cons of using different nanomaterials for different types of treatment


Pharmaceutical scientists, biomaterials scientists, toxicologists, biomedical engineers, medicinal chemists and postgraduate students specializing in the areas of nanomedicine, bionanomaterials and nanotechnology applications in healthcare

Table of Contents

  • 1. Multifunctional nanoparticles for successful targeted drug delivery and diagnostics across the blood-brain barrier
    2. Trastuzumab drug delivery systems for Magnetic Resonance detection
    3. A novel approach for drug targeting: core-shell type lipid-polymer hybrid nanocarriers
    4. Multifunctional core-shell polymeric and hybrid nanoparticles as anticancer nanomedicines
    5. Multifunctional Core Shell Nanostructures as Theranostics
    6. Prospects of precision therapy and imaging of glioblastoma in vivo using quantum dots
    7. Mesoporous silica nanoparticles as drug carrier for cancer therapy and bioimaging
    8. Current approaches in breast cancer targeting pharmaceuticals
    9. Novel multifunctional nano-carrier mediated co-delivery for targeting and treatment of prostate cancer
    10. Nanoparticles and their promising applications in therapeutics and diagnostics of various neurological disorders
    11. Conventional and current imaging techniques in cancer research and clinics
    12. Synthetic microbial ecology and nanotechnology for production of taxol and its precursors: a step towards sustainable production of cancer therapeutics
    13. Polymeric and lipid-based systems for controlled drug release: an engineering point of view
    14. Mercaptosuccinic Acid Capped CdTe/CdS/ZnS nanoparticles Core-Double Shell Quantum Dots: Structural Optical Imaging and Cytotoxic Assessment on Normal and Cancer Cells
    15. Quantum Dots in Pharmaceutical Sciences
    16. Liposomes and Micelles as Lipid Based Nanocarriers for Diagnostic and Imaging Purposes
    17/ Dendrimer-drug conjugates: synthesis, characterization and application in anticancer drug delivery

Product details

  • No. of pages: 692
  • Language: English
  • Copyright: © Elsevier 2018
  • Published: November 30, 2017
  • Imprint: Elsevier
  • eBook ISBN: 9780128136706
  • Paperback ISBN: 9780128136690

About the Editor

Alexandru Grumezescu

Dr. Grumezescu is Assistant Professor at the Department of Science and Engineering of Oxide Materials and Nanomaterials, in the Faculty of Applied Chemistry and Materials Science, with a second affiliation to the Faculty of Medical Engineering, at the Politehnica University of Bucharest in Romania. He is an experienced and oft-published researcher and editor in the field of nano and biomaterials, and he is the Editor-in-Chief of three journals: Biointerface Research in Applied Chemistry, Letters and Applied NanoBioScience, and Biomaterials and Tissue Engineering Bulletin. He also serves as editor or guest editor for several notable journals. Dr. Grumezescu has published 150 peer-reviewed papers, 20 book chapters, 6 co-authored books and 11 edited books.

Affiliations and Expertise

Assistant Professor, Department of Science and Engineering of Oxide Materials and Nanomaterials, Faculty of Applied Chemistry and Materials Science and Faculty of Medical Engineering, Politehnica University of Bucharest, Romania

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