Dendrimer-Based Nanotherapeutics

Dendrimer-Based Nanotherapeutics

1st Edition - April 14, 2021

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  • Editor: Prashant Kesharwani
  • eBook ISBN: 9780128212516
  • Paperback ISBN: 9780128212509

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Dendrimer-Based Nanotherapeutics delivers a comprehensive resource on the use of dendrimer-based drug delivery. Advances in the application of nanotechnology in medicine have given rise to multifunctional smart nanocarriers that can be engineered with tunable physicochemical characteristics to deliver one or more therapeutic agent(s) safely and selectively to cancer cells, including intracellular organelle-specific targeting. This book compiles the contribution of dendrimers in the field of nanotechnology to aid researchers in exploring dendrimers in the field of drug delivery and related applications. This book covers the history of the area to the most recent research. The starting chapter covers detailed information about basic properties about dendrimers i.e. properties, nomenclature, synthesis methods, types, characterization of dendrimers, safety and toxicity issues of dendrimers. Further chapters discuss the most recent advancements in the field of dendrimer i.e. dendrimer-drug conjugates, PEGylated dendrimer, dendrimer surface engineering, dendrimer hybrids, dendrimers as solubility enhancement, in targeting and delivery of drugs, as photodynamic therapy, in tissue engineering, as imaging contrast agents, as antimicrobial agents, advances in targeted dendrimers for cancer therapy and future considerations of dendrimers. Dendrimer-Based Nanotherapeutics will help the readers to understand the most recent progress in the field of dendrimer-based research, suitable for pharmaceutical scientists, advanced students, and those working in related healthcare fields.

Key Features

  • Discusses various routes such as oral, pulmonary, transdermal, delivery and local administration of dendrimer delivery of bioactive
  • Explores a wide range of applications of dendrimer-based drug delivery using the latest advancements in nanomedicine
  • Provides the most recent research on dendrimers as well as context and background, providing a useful resource for all levels of researcher


Young scientists starting to work in the field of dendrimers. Academic researchers and students working on the basic research field at the Chemistry Department, Engineering departments (for example, Chemical Engineering, Materials Science and Engineering, and Biomedical Engineering, etc.), and the Pharmaceutics Department. Researcher and graduate students working in the area of nanotechnology, pharmaceutical sciences, polymer science, chemistry, materials, engineering, medicine, and physicians can read or go through the recent advances in this field of research

Table of Contents

  • 1. History and introduction of dendrimers
    2. Properties of dendrimers
    3. Biological interactions of dendrimers
    4. Dendrimer nomenclature and synthesis methods
    5. Types of dendrimers
    6. Characterization of dendrimers
    7. Safety and toxicity issues of dendrimers
    8. Dendrimer-drug conjugate
    9. PEGylated dendrimer
    10. Surface engineered dendrimers in targeting and delivery of drugs
    11. Dendrimer hybrids with other nanocarriers
    12. Dendrimers for solubility enhancement
    13. Dendrimers for gene therapy
    14. Dendrimer for photodynamic therapy
    15. Dendrimers in tissue engineering
    16. Dendrimer as imaging contrast agents
    17. Dendrimer as antimicrobial agents
    18. Theranostic dendrimer for cancer
    19. Dendrimer as anti-inflammatory prodrugs
    20. Advances in targeted dendrimers for cancer therapy and challenges for clinical translation
    21. Conclusion and future considerations of dendrimers

Product details

  • No. of pages: 484
  • Language: English
  • Copyright: © Academic Press 2021
  • Published: April 14, 2021
  • Imprint: Academic Press
  • eBook ISBN: 9780128212516
  • Paperback ISBN: 9780128212509

About the Editor

Prashant Kesharwani

Dr. Prashant Kesharwani is Assistant Professor of Pharmaceutics at the School of Pharmaceutical Education and Research, Jamia Hamdard University, New Delhi, India. He has more than 250 international publications in well reputed journals and 13 international books (Elsevier). He is a recipient of several internationally acclaimed awards viz ‘Ramanujan Fellowship, DST, India-2017’, ‘Excellence Research Award 2014’, ‘Young Innovator Award (Gold medal) 2012’, ‘International Travel Award/Grant from DST (New Delhi) and INSA (CCSTDS, Chennai) 2012’. He has received an ICMR Senior Research Fellowship (PhD) and AICTE Junior Research Fellowship (M. Pharm.). He has presented many invited talks and oral presentations at prestigious scientific peer-conferences, received international acclaims and awards for research contribution, supervised students/junior researchers and actively participated in outreach and scientific dissemination for the service of wider community.

Affiliations and Expertise

Prashant Kesharwani, Assistant Professor, School of Pharmaceutical Education and Research, Jamia Hamdard University, New Delhi, India

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