Dancing Protein Clouds: Intrinsically Disordered Proteins in the Norm and Pathology - 1st Edition - ISBN: 9780128168516

Dancing Protein Clouds: Intrinsically Disordered Proteins in the Norm and Pathology, Volume 166

1st Edition

Serial Volume Editors: Vladimir Uversky
Hardcover ISBN: 9780128168516
Imprint: Academic Press
Published Date: 15th September 2019
Page Count: 300
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Table of Contents

1. Protein intrinsic disorder and structure-function continnum
Vladimir N. Uversky
2. Intrinsic disorder associated with 14-3-3 proteins and their partners
Nikolai N. Sluchanko
3. Intrinsically Disordered Proteins and Phenotypic Switching in Cancer: The Role of Conformational Dynamics
Prakash Kulkarni
4. Translational diffusion of flexible molecules
Irina Nesmelova
5. Disorder-to-Order Transition During Amyloid Formation
Samrat Mukhopadhyay
6. Impacts of Mitochondrial Dysfunction and Oxidative Stress on Intrinsically Disordered Proteins in Alzheimer´s and Parkinson´s Disease Pathologies
Orkid Coskuner
7. Shear-Induced Amyloid Formation of IDPs in the Brain
Conrad N. Trumbore
8. Roles of intrinsic disorder in sarcomere formation and function
Dmitri Tolkatchev and Alla S. Kostyukova
9. Computational prediction of functions of intrinsically disordered regions
Lukasz Kurgan
10. The Balance between Liquid-Liquid Phase Separation and Fibrillization in Neurodegenerative Diseases
Benjamin Wolozin
11. Involvement of intrinsically disordered proteins in mechanism of viral pathogenesis and control
Rajanish Giri


Dancing Protein Clouds: Intrinsically Disordered Proteins in the Norm and Pathology, Volume 166 in the Progress in Molecular Biology and Translational Science series, provides the most topical, informative and exciting monographs available on a wide variety of research topics relating to Dancing protein clouds. Specific chapters cover topics such as Protein intrinsic disorder and structure-function continuum, Intrinsic disorder associated with 14-3-3 proteins and their partners, Intrinsically disordered proteins and phenotypic switching in cancer: The role of conformational dynamic, translational diffusion of flexible molecules, The impacts of mitochondrial dysfunction and oxidative stress on intrinsically disordered proteins in Alzheimer´s and Parkinson´s disease pathologies, and more.

Key Features

  • Includes comprehensive coverage of molecular biology
  • Presents ample use of tables, diagrams, schemata and color figures to enhance the reader's ability to rapidly grasp the information provided
  • Contains contributions from renowned experts in the field


Each volume in the series is useful for scientists working actively in a field, including those at levels ranging from graduate student to senior investigator. Also appropriate for new investigators to a field who wish to familiarize themselves with the latest work


No. of pages:
© Academic Press 2019
Academic Press
Hardcover ISBN:

Ratings and Reviews

About the Serial Volume Editors

Vladimir Uversky Serial Volume Editor

Vladimir Uversky is an Associate Professor at the Department of Molecular Medicine of University of South Florida, College of Medicine, and a Leading Scientist at the Institute for Biological Instrumentation, Russian Academy of Sciences. He received his B.S. and M.S. degrees in Physics from Leningrad State University in Russia in 1986, then, completed Ph.D. and Doctor of Sciences (D.Sc.) degrees in Physics and Mathematics (field of study - Biophysics) at the Moscow Institute of Physics and Technology (1991) and the Institute Experimental and Theoretical Biophysics of the Russian Academy of Sciences (1998), respectively. He spent his early career working on protein folding at Institute of Protein Research and the Institute for Biological Instrumentation (Russia). In 1998, he moved to the University of California Santa Cruz to study protein folding, misfolding, protein conformation diseases, and protein intrinsic disorder phenomenon. In 2004, he was invited to join the Indiana University School of Medicine to primary work on the intrinsically disordered proteins. Since 2010, he is with USF, where he continues to study intrinsically disordered proteins and analyze protein folding and misfolding processes. He has authored over 750 scientific publications and edited several books and book series on protein structure, function, folding and misfolding. He is the editor of several scientific journals. In 2014, 2015, 2016, and 2017, he was included by the Thomson Reuters to the list of Highly Cited Researchers.

Affiliations and Expertise

University of South Florida, USA