Table of Contents

1.Collection and handling of blood

2. Reference ranges and normal values

3. Basic haematological techniques

4. Preparation and staining methods for blood and bone marrow films

5. Blood cell morphology in health and disease

6. Supplementary techniques including blood parasite diagnosis

7. Bone marrow biopsy

8. Molecular and cytogenetic analysis

9. Iron deficiency anaemia and iron overload

10. Investigation of megaloblastic anaemia: cobalamin, folate and metabolite status

11. Laboratory methods used in the investigation of the haemolytic anaemias

12. Investigation of the hereditary haemolytic anaemias: membrane and enzyme abnormalities

13. Acquired haemolytic anaemias

14. Investigation of abnormal haemoglobins and thalassaemia

15. Erythrocyte and leucocyte cytochemistry

16. Immunophenotyping

17. Diagnostic radioisotopes in haematology

18. Investigation of haemostasis

19. Investigation of a thrombotic tendency

20. Laboratory control of anticoagulant, thrombolytic and antiplatelet therapy

21. Blood cell antigens and antibodies: erythrocytes, platelets and granulocytes

22. Laboratory aspects of blood transfusion

23. Approach to the diagnosis and classification of blood diseases

24. Laboratory organization and management

25. Quality assurance

26. Haematology in under-resourced laboratories

27. Appendix


Churchill Livingstone
eBook ISBN:
eBook ISBN:
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About the authors

Barbara Bain

Affiliations and Expertise

Professor in Diagnostic Haematology, St Mary’s Hospital Campus of Imperial College Faculty of Medicine; Honorary Consultant Haematologist, St Mary's Hospital and Imperial College Healthcare NHS Trust, London, UK

Imelda Bates

Affiliations and Expertise

Professor of Haematology, Liverpool School of Tropical Medicine, University of Liverpool, Liverpool, UK

Mike Laffan

Affiliations and Expertise

Professor of Haemostasis and Thrombosis, Honorary Consultant in Haematology, Division of Investigative Medicine, Imperial College School of Medicine, London, UK

S. Lewis

Affiliations and Expertise

Emeritus Reader in Haematology, University of London; Senior Research Fellow in Haematology, Imperial College School of Medicine, Hammersmith Hospital, London, UK