Cytoplasmic Genes and Organelles

1st Edition - January 1, 1972
Author: Ruth Sager
Language: English
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 1 5 1 1 4 - 6

Cytoplasmic Genes and Organelles is about cytoplasmic genes: what they are and what they do. It applies the concepts and methods of cytoplasmic genetics to the problems of cell and… Read more

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Cytoplasmic Genes and Organelles is about cytoplasmic genes: what they are and what they do. It applies the concepts and methods of cytoplasmic genetics to the problems of cell and molecular biology to which they can uniquely contribute. It shows geneticists the many attractive problems in this area awaiting their attention; cell biologists and biochemists the usefulness of cytoplasmic genetic analysis in their endeavors; and students the potential power of an integrated experimental approach using cytoplasmic genes together with the more conventional tools of biochemistry and electron microscopy in the investigation of organelle biogenesis. The book treats the following aspects of cytoplasmic genetic systems: (1) the properties of cytoplasmic DNA; (2) the genetic analysis of cytoplasmic systems; and (3) the functions of cytoplasmic genes in organelle biogenesis. The opening chapter summarizes the principal findings to provide readers with a bird's eye view of the subject. Subsequent chapters cover topics such as cytoplastmic DNAs; cytoplasmic genes in Chlamydomonas; mitochondrial genetics of yeast; cytoplasmic genes in higher plants; the role of mitochondrial genes in mitochondrial biogenesis; and cytoplasmic genes and cell heredity.

PrefaceAcknowledgments 1. What are Cytoplasmic Genes Cytoplasmic DNA's Formal Genetics of Cytoplasmic Systems 2. Cytoplasmic DNA's Identification of Organelle DNA's Organelle DNA's of Plant Cells Identification of Mitochondrial DNA's The Uniqueness of Organelle DNA Size and Circularity of Organelle DNA Genomic Size of Organelle DNA's Heritable Alteration in Yeast Mitochondrial DNA Replication and Repair of Organelle DNA's Control of Replication of Organelle DNA's Loss of Organelle DNA Concluding Remarks Suggested Review Articles ReferencesGenetic Analysis of Cytoplasmic Systems 3. Cytoplasmic Genes in Chlamydomonas Introduction Some Properties of Chlamydomonas Transmission of Cytoplasmic Genes in Chlamydomonas: A Summary Genetic Analysis of Cytoplasmic Genes in Chlamydomonas Persistent Heterozygotes Concluding Remarks Suggested Review Articles References 4. Mitochondrial Genetics of Yeast Sexual Life of Saccharomyces cerevisiae Early Hints of Mitochondrial Heredity Cytoplasmic Petites Induction of Cytoplasmic Petites by Other Methods Suppressive Petites Studies of Suppressiveness at the Cellular Level Recent Developments in Mitochondrial Genetics of Yeast Concluding Remarks Suggested Review Articles References 5. Cytoplasmic Genes in Neurospora and Other Fungi Genetic Analysis of Poky and Related Strains of Neurospora Biochemical Studies of Poky Studies of Cytoplasmic Mutants by Microinjection Studies of Cytoplasmic Heredity in Podospora Studies of Cytoplasmic Heredity in Aspergillus Concluding Remarks Suggested Review Articles References 6. Cytoplasmic Genes in Higher Plants Chloroplast Variegation and Pollen Sterility in Zea mays Inheritance of Pollen Sterility Biparental Inheritance in Pelargonium Cytological Identification of "Mixed" Cells Epilobium and the Plasmone Hypothesis Plastid Autonomy in Oenothera The Role of Plastid Genes in Evolution in the Genus Oenothera Concluding Remarks Suggested Review Articles References Patterns of Transmission of Cytoplasmic Genes: A Summary Mutagenesis Phenotypes Identification Preferential TransmissionCytoplasmic Genes and Organelle Biogenesis Introductory Remarks 7. The Role of Mitochondrial Genes in Mitochondrial Biogenesis Structural Organization Mitochondrial RNA's and Ribosomes Origin of Mitochondrial Proteins Summary Suggested Review Articles References 8 . The Role of Cytoplasmic Genes in the Biogenesis of Chloroplasts Molecular Composition and Structure of Chloroplasts Chemical Composition of the Chloroplast Chloroplast Ribosomes and RNA's Origin of Chloroplast Proteins Concluding Remarks Suggested Review Articles References Concluding Remarks 9. Cytoplasmic Genes and Cell Heredity Some Postulated Advantages to Cells of Cytoplasmic Genomes Aspects of Cell Heredity Not Previously Considered Some Recent Applications of Cytoplasmic Genetics Concluding Remarks ReferencesAppendix Cesium Chloride Density Gradient Centrifugation Density Transfer Method to Examine the Molecular Pattern of DNA Replication Nearest-Neighbor Frequency Analysis Kinetics of Renaturation of DNA ReferencesGlossarySubject Index