Cytoplasmic Genes and Organelles

Cytoplasmic Genes and Organelles

1st Edition - January 1, 1972

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  • Author: Ruth Sager
  • eBook ISBN: 9780323151146

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Cytoplasmic Genes and Organelles is about cytoplasmic genes: what they are and what they do. It applies the concepts and methods of cytoplasmic genetics to the problems of cell and molecular biology to which they can uniquely contribute. It shows geneticists the many attractive problems in this area awaiting their attention; cell biologists and biochemists the usefulness of cytoplasmic genetic analysis in their endeavors; and students the potential power of an integrated experimental approach using cytoplasmic genes together with the more conventional tools of biochemistry and electron microscopy in the investigation of organelle biogenesis. The book treats the following aspects of cytoplasmic genetic systems: (1) the properties of cytoplasmic DNA; (2) the genetic analysis of cytoplasmic systems; and (3) the functions of cytoplasmic genes in organelle biogenesis. The opening chapter summarizes the principal findings to provide readers with a bird's eye view of the subject. Subsequent chapters cover topics such as cytoplastmic DNAs; cytoplasmic genes in Chlamydomonas; mitochondrial genetics of yeast; cytoplasmic genes in higher plants; the role of mitochondrial genes in mitochondrial biogenesis; and cytoplasmic genes and cell heredity.

Table of Contents

  • Preface


    1. What are Cytoplasmic Genes

    Cytoplasmic DNA's

    Formal Genetics of Cytoplasmic Systems

    2. Cytoplasmic DNA's

    Identification of Organelle DNA's

    Organelle DNA's of Plant Cells

    Identification of Mitochondrial DNA's

    The Uniqueness of Organelle DNA

    Size and Circularity of Organelle DNA

    Genomic Size of Organelle DNA's

    Heritable Alteration in Yeast Mitochondrial DNA

    Replication and Repair of Organelle DNA's

    Control of Replication of Organelle DNA's

    Loss of Organelle DNA

    Concluding Remarks

    Suggested Review Articles


    Genetic Analysis of Cytoplasmic Systems

    3. Cytoplasmic Genes in Chlamydomonas


    Some Properties of Chlamydomonas

    Transmission of Cytoplasmic Genes in Chlamydomonas: A Summary

    Genetic Analysis of Cytoplasmic Genes in Chlamydomonas

    Persistent Heterozygotes

    Concluding Remarks

    Suggested Review Articles


    4. Mitochondrial Genetics of Yeast

    Sexual Life of Saccharomyces cerevisiae

    Early Hints of Mitochondrial Heredity

    Cytoplasmic Petites

    Induction of Cytoplasmic Petites by Other Methods

    Suppressive Petites

    Studies of Suppressiveness at the Cellular Level

    Recent Developments in Mitochondrial Genetics of Yeast

    Concluding Remarks

    Suggested Review Articles


    5. Cytoplasmic Genes in Neurospora and Other Fungi

    Genetic Analysis of Poky and Related Strains of Neurospora

    Biochemical Studies of Poky

    Studies of Cytoplasmic Mutants by Microinjection

    Studies of Cytoplasmic Heredity in Podospora

    Studies of Cytoplasmic Heredity in Aspergillus

    Concluding Remarks

    Suggested Review Articles


    6. Cytoplasmic Genes in Higher Plants

    Chloroplast Variegation and Pollen Sterility in Zea mays

    Inheritance of Pollen Sterility

    Biparental Inheritance in Pelargonium

    Cytological Identification of "Mixed" Cells

    Epilobium and the Plasmone Hypothesis

    Plastid Autonomy in Oenothera

    The Role of Plastid Genes in Evolution in the Genus Oenothera

    Concluding Remarks

    Suggested Review Articles


    Patterns of Transmission of Cytoplasmic Genes: A Summary




    Preferential Transmission

    Cytoplasmic Genes and Organelle Biogenesis

    Introductory Remarks

    7. The Role of Mitochondrial Genes in Mitochondrial Biogenesis

    Structural Organization

    Mitochondrial RNA's and Ribosomes

    Origin of Mitochondrial Proteins


    Suggested Review Articles


    8 . The Role of Cytoplasmic Genes in the Biogenesis of Chloroplasts

    Molecular Composition and Structure of Chloroplasts

    Chemical Composition of the Chloroplast

    Chloroplast Ribosomes and RNA's

    Origin of Chloroplast Proteins

    Concluding Remarks

    Suggested Review Articles


    Concluding Remarks

    9. Cytoplasmic Genes and Cell Heredity

    Some Postulated Advantages to Cells of Cytoplasmic Genomes

    Aspects of Cell Heredity Not Previously Considered

    Some Recent Applications of Cytoplasmic Genetics

    Concluding Remarks



    Cesium Chloride Density Gradient Centrifugation

    Density Transfer Method to Examine the Molecular Pattern of DNA Replication

    Nearest-Neighbor Frequency Analysis

    Kinetics of Renaturation of DNA



    Subject Index

Product details

  • No. of pages: 420
  • Language: English
  • Copyright: © Academic Press 1972
  • Published: January 1, 1972
  • Imprint: Academic Press
  • eBook ISBN: 9780323151146

About the Author

Ruth Sager

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