Key Features

  • Avoid potential errors in diagnosis with a full chapter that offers expert approaches to specimen collection and processing.
  • Arrive at more accurate diagnoses with the aid of step-by-step algorithms plus hundreds of illustrations - including multiple images for each phenomenon representing a broad range of stains and magnifications.
  • Achieve optimal diagnostic certainty by viewing correlations between Pap, Diff-Quick (Romanowsky), and immunocytochemical stain for every type of serous effusion.
  • Recognize the difference in cell samples yielded after washing the serous cavity with saline or balanced salt solution versus effusion fluid.
  • Understand the advantages and disadvantages of Pap stains versus Diff-Quick stains in FNA evaluations.
  • Remain up to date with the latest technologies such as liquid based cytology (SurePath™) and ThinPrep™.
  • Easily apply principles to real-life practice by reviewing detailed histories.
  • Quickly locate the guidance you need with a color-coded chapter system.
  • Focus on the most important points with user-friendly highlighted boxes.

Table of Contents

1. Introduction

2. The panorama of different faces of mesothelial cells

3. Approach to diagnostic cytopathology of serous effusions

4. Diagnostic pitfalls in effusion fluid cytology

5. Immunocytochemistry of effusion fluids: introduction to SCIP approach

6. Reactive conditions

7. Diagnostic cytopathology of peritoneal washing

8. Mesothelioma

9. Metastatic carcinoma in effusions

10. Metastaic sarcomas, melanoma, and other non-epithelial malignancies

11. Where do they come from? Evaluation of unknown primary site of origin

12. Hematolyphoid disorders

13. Flow cytometry, molecular techniques, and other special techniques

Appendix 1: Collection and processing of serous cavity fluids for cytopathologic evaluation

Appendix 2: Immunocytochemistry of effusions - processing and commonly used immunomarkers



No. of pages:
© 2007
Print ISBN:
Electronic ISBN:

About the authors

Vinod Shidham

Affiliations and Expertise

Professor, Vice-chair, and Director of Cytopathology, Cytotechnology School, Cytopathology fellowship, & GI path fellowship, Dept of Pathology, Wayne State University School of Medicine & Detroit Medical Center, Detroit, MI, USA

Barbara Atkinson

Affiliations and Expertise

Chair and Professor, Department of Pathology and Laboratory Medicine, University of Kansas School of Medicine, Kansas City, KS, USA