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Cytokine Effector Functions in Tissues - 1st Edition - ISBN: 9780128042144, 9780128042199

Cytokine Effector Functions in Tissues

1st Edition

Editors: Maria Foti Massimo Locati
Paperback ISBN: 9780128042144
eBook ISBN: 9780128042199
Imprint: Academic Press
Published Date: 17th July 2017
Page Count: 304
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Cytokine Effector Functions in Tissues discusses the cytokines networks in the context of the specific-tissue environment. It is an up-to-date collection of articles that addresses the specific issue of how the cytokines are able to condition tissue specific homeostasis. The book helps the reader understand how cytokines network inside the tissues and highlights whether tissue-protection or exacerbation will be finally controlled. It describes the cytokines detected and regulated in different tissues, such as the brain, lungs, spleen, liver, pancreas and intestine, also addressing the issue of timing in specific cell types.

Key Features

  • Categorizes the cytokines based primarily on tissue and target cells
  • Emphasizes different roles and outcomes observed during innate and adaptive response
  • Represents a rapid guide to cytokines in health and disease in tissue and organ context
  • Presents a different view on how known mediators may work if analyzed in a different perspective, determining the final outcome on tissue-specific target cells


Researchers in immunology, cytokines research, molecular biology, genetics, biochemistry, genome-wide association studies, pathobiology, diagnostic and clinical applications of all known interleukins, hematopoietic factors, growth factors, cytotoxins, interferons, new cytokines, and chemokines

Table of Contents


  Maria Foti

Cytokines as Tissue Regulators in Health and Disease

  Maria Foti

I. Cytokine Tissue Specific Regulation

1. Cytokine and the Adipose Tissue

  Isabelle Wolowczuk

2. Cytokine and Ovary

  Nicolas Michel Orsi

3. Cytokine and the Liver

  Pietro Invernizzi

II. Cytokines Regulation in Disease

4. Cytokines in Osteoarthritis

  Mohit Kapoor

5. Cytokines in Atherosclerosis

  Dipak Purshottam Ramji

6. Cytokines and Diabetes

  Juan F. Navarro-Gonzalez

7. Cytokines and Sarcoidosis

  Paul S. Thomas

8. Cytokine and Nerve Degeneration

  P. Dubovy

9. Cytokine and Skeletal Muscle Disease

  Boel De Paepe

10. Airway epithelial cytokines in asthma and chronic obstructive pulmonary diseas

  Rakesh K. Kumar

11. Eosinophils Cytokines and Allergies

  Paige Lacy

12. Cytokine in Transplantation

  Geoff Hill and Kate Markey

III. Cytokines and Therapeutic Applications

13. Cytokine Therapies in CANCER

  Ruth Ganss

14. MSCs Cytokines as cellular Therapies

  Dobroslav Kyurkchiev


No. of pages:
© Academic Press 2017
17th July 2017
Academic Press
Paperback ISBN:
eBook ISBN:

About the Editors

Maria Foti

Maria Foti

Maria Foti is Assistant Professor at the University of Milano-Bicocca. She is an internationally recognized immunologist/molecular biologist with experience in both academic science and biotechnology. She has worked for several years in the field of molecular immunology and cell biology of Dendritic Cells. She studied the molecular events associated with Dendritic cell early responses, suggesting the role of Dendritic Cells as the key players in the innate immune responses. Dr. Foti's lab has a focus on cytokine research including the role of cytokines produced by Dendritic cells in response to pathogens. She has been also involved in projects for the selection of biomarkers using the microarray technology in the field of cancer and Autoimmunity.

Affiliations and Expertise

University of Milano-Bicocca, Italy

Massimo Locati

Massimo Locati

Massimo Locati is Full Professor of General Pathology and Immunology at the Department of Medical Biotechnologies and Translational Medicine at the University of Milan and chief of the Leukocyte Biology Lab at the Humanitas Clinical and Research Center in Rozzano, Milan. His current scientific research interests are represented by cellular and molecular mechanisms involved in resolution of inflammation, identification of the biological role of chemokine decoy receptors, definition of chemokine receptors signalling properties and associated transcriptional events investigation of molecular mechanisms supporting macrophage activation and polarization, and role of regulatory RNA in innate immunity and immune- mediated diseases .

Affiliations and Expertise

Department of Medical Biotechnonology,University of Milan, Milan, Italy

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