Current Topics in Experimental Endocrinology - 1st Edition - ISBN: 9780121532017, 9781483217338

Current Topics in Experimental Endocrinology

1st Edition

Volume 1

Editors: L Martini V. H. T. James
eBook ISBN: 9781483217338
Imprint: Academic Press
Published Date: 28th February 1972
Page Count: 308
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Current Topics in Experimental Endocrinology, Volume 1 provides a review on experimental endocrinology. The book discusses the basic concepts of saturation analysis techniques; the concept of how steroid hormones might influence the differentiation of certain brain structures instrumental in the control of gonadotropin secretion; and trends in the physiology of the posterior pituitary. The text also describes role of thymosin and other thymic factors in the development, maturation, and functions of lymphoid tissue; the chemistry and comparative chemistry of calcitonin, factors affecting its secretion and metabolic degradation, and the results of its preliminary therapeutic application in the complex situation of disordered bone metabolism found in Paget's disease. The chemical nature and the importance of the long-acting thyroid stimulator; the endocrinological implications of prostaglandins; and effects of ovarian hormones at the subcellular level are also encompassed. Endocrinologists and students taking related courses will find the book invaluable.

Table of Contents

List of Contributors


Basic Concepts of Saturation Analysis Techniques

I. Introduction

II. Saturation Assay

III. Some Practical Aspects of Saturation Assay Procedures

IV. Conclusions


Steroid Hormones and the Differentiation of the Central Nervous System

I. General Introduction

II. The Androgen-sterilized Rat

III. The Possible Site of Action of Androgen

IV. The Possible Mechanism of Action of Androgen

V. Effects of Neonatal Treatment with Steroid Hormones Other Than Androgen on Subsequent Fertility

VI. Protection Against Steroid-Induced Sterility

VII. Summary and Conclusions


Recent Trends in the Physiology of the Posterior Pituitary

I. Introduction

II. Neurosecretion

III. Neurophysin

IV. Vasopressin

V. Oxytocin

VI. The Natriuretic Hormone

VII. Summary and Conclusions


Role of Thymosin and Other Thymic Factors in the Development, Maturation, and Functions of Lymphoid Tissue

I. Introduction

II. Embryonic Development and Differentiation of the Thymus Gland

III. Role of the Thymus in the Development, Maturation, and Function of the Lymphoid System

IV. Thymic Malfunction: Clinical Disorders

V. Mechanism of Action of the Thymus

VI. Concluding Comments



I. Introduction

II. The Chemistry of Calcitonins

III. Control of Secretion of Calcitonin

IV. Therapeutic Uses of Calcitonin


The Long-Acting Thyroid Stimulator

I. Introduction

II. Clinical Importance of LATS

III. Chemical Nature of LATS

IV. Effects of LATS and Its Active Fragments in Relation to Actions of TSH

V. Absorption of LATS by Thyroid Extracts


Endocrinological Implications of Prostaglandins

I. Introduction

II. Tropic Hormone Effects

III. Neuroendocrinological Considerations

IV. Posterior Pituitary

V. Exocrine Hormone Interaction

VI. Actions on Lipid and Carbohydrate Metabolism

VII. Conclusions


Effects of Ovarian Hormones at the Subcellular Level

I. Introduction

II. Estrogens

III. Progestins

IV. Hormone-Receptor Interaction Pattern and Its Biochemical Significance


Author Index

Subject Index


No. of pages:
© Academic Press 1971
Academic Press
eBook ISBN:

About the Editor

L Martini

V. H. T. James

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