Current Topics in Cellular Regulation - 1st Edition - ISBN: 9780121528294, 9781483217284

Current Topics in Cellular Regulation, Volume 29

1st Edition

Editors: Bernard L. Horecker Earl R. Stadtman
eBook ISBN: 9781483217284
Imprint: Academic Press
Published Date: 28th May 1988
Page Count: 364
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Table of Contents


Control of Metabolism by Dynamic Macromolecular Interactions


I. Introduction


II. Control of Metabolic Pathways


III. Dynamically Organized Enzyme Systems


IV. Energetic Aspects


V. Concluding Remarks


References


Ligand Binding and Multienzyme Complex Formation Between Ornithine Carbamoyltransferase and Arginase from Saccharomyces cerevisiae


I. Introduction


II. Regulation of Arginine Metabolism in Saccharomyces cerevisiae


III. Quaternary Structure of Yeast OTCase and Arginase


IV. Quaternary Structure of the OTCase-Arginase Multienzyme Complex


V. Test for an Ornithine Isosteric Effector Site


VI. Intrinsic and Extrinsic Effects


References


Regulation of Fatty Acid Uptake and Synthesis in Mammary and Adipose Tissues: Contrasting Roles for Cyclic AMP


I. Introduction


II. The Cyclic AMP Economy of Mammary Tissue During Lactation


III. Acute Regulation of Fatty Acid Uptake and Biosynthesis Processes in Lactating Mammary Tissue


IV. Regulation of Acetyl-CoA Carboxylase


V. Cyclic AMP-Dependent Protein Phosphorylation in Mammary Epithelial Cells


VI. Concluding Remarks


References


Structural and Functional Relationships of Guanosine Triphosphate Binding Proteins


I. Introduction


II. The Role of Guanine Nucleotide Binding Proteins in Hormonal Regulation of Adenylate Cyclase Activity


III. The Role of Guanine Nucleotide Binding Proteins in Visual Signal Transmission


IV. Novel Guanine Nucleotide Binding Proteins with Other Functions, and Known Guanine Nucleotide Binding Proteins with Novel Functions


V. G Protein Structures


VI. Summary


References


The Glycogen Storage Disease (gsd/g


Description

Current Topics in Cellular Regulation: Volume 29 is a collection of papers that deals with dynamic macromolecular interactions, ligand binding, multi-enzyme complex formation, the regulation of fatty acid uptake, and synthesis in mammary or adipose tissues. Other papers explain the functional relationships of guanosine triphosphate binding proteins, the glycogen storage disease, the regulation of the pentose phosphate pathway in the brain, as well as the regulation of carotenoid biosynthesis. One paper discusses the dissociable enzyme complexes stabilized by weak interactions, particularly on the interaction of cytosolic enzymes with the contractile apparatus, with membranes, or with functionally related enzymes. Another paper investigates the mechanism of acute regulation, in mammary epithelial cells, of the processes which collaborate to supply fatty acids for esterification to form glycerolipids (which is predominantly triacylglycerol). Glycerolipids comprise mostly the total lipid content of the secretory product of those cells—mammalian milk. The paper notes that a counter-regulatory hormone collaborating with insulin in the regulation of lipid metabolism in the lactating mammary cell, does not act via cyclic AMP. The collection can prove beneficial for biochemists, micro-biologists, bio-physicists, cellular researchers, and academicians involved in the study of cellular biology or physiology.


Details

No. of pages:
364
Language:
English
Copyright:
© Academic Press 1988
Published:
Imprint:
Academic Press
eBook ISBN:
9781483217284

Ratings and Reviews


About the Editors

Bernard L. Horecker Editor

Earl R. Stadtman Editor