Current Topics in Cellular Regulation - 1st Edition - ISBN: 9780121528164, 9781483217154

Current Topics in Cellular Regulation, Volume 16

1st Edition

Editors: Bernard L. Horecker Earl R. Stadtman
eBook ISBN: 9781483217154
Imprint: Academic Press
Published Date: 28th June 1980
Page Count: 332
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Table of Contents


List of Contributors


Brain Hexokinase, the Prototype Ambiquitous Enzyme


I. Introduction


II. Subcellular Distribution of Hexokinase in Brain Homogenates


III. Cytoplasmic and Mitochondrial Forms of Brain Hexokinase


IV. Mitochondrial Hexokinase


V. Ambiquitous Behavior of Brain Hexokinase


VI. The Molecular Basis for the Specific Binding of Brain Hexokinase by the Outer Mitochondrial Membrane


VII. Hexokinase Activity as a Reflection of Glycolytic Capacity


VIII. Concluding Comments


References


Appendix: Ambiquitous Behavior—A Biological Phenomenon of General Significance?


Appendix References


Compartmentation of Hexokinase and Creatine Phosphokinase, Cellular Regulation, and Insulin Action


I. Introduction


II. Experimental Evidence for Bound Hexokinase as a Compartmental Control Point


III. Bound Creatine Phosphokinase: Experimental Evidence for Compartmentation


IV. The Hexokinase-Mitochondrial Theory of Insulin Action and Hormonal Metabolic Control


References


Cytochrome c Methylation: Enzymology and Biologic Significance


I. Opening Remarks on Protein Methylation


II. Cytochrome c Methylation


III. Closing Remarks


References


Enzyme Organization in the Polyaromatic-Biosynthetic Pathway: The Arom Conjugate and Other Multienzyme Systems


I. Introduction


II. The Polyaromatic-Biosynthetic Multienzyme System


III. Phylogenetic Aspects of Enzyme Organization in the Polyaromatic Pathway


IV. Concluding Remarks


Appendix: Enzyme Organization in Vivo: Some Thermodynamic-Kinetic Perspectives


References


Proteolysis in Bacterial Sporulation


I. Introduction


II. T


Description

Current Topics in Cellular Regulation, Volume 16 considers the advances in the general area of cellular regulation.

This book discusses the subcellular distribution of hexokinase in brain homogenates and experimental evidence for bound hexokinase as a compartmental control point. The enzymology and biologic significance of cytochrome c methylation, polyaromatic-biosynthetic multienzyme system, and proteolytic modulation of gene expression in sporulation are also elaborated. This text likewise covers the occurrence of cyclic nucleotide-synthesizing and -degrading enzymes in the mammalian brain and calcium ion as a positive effector of oocyte maturation.

This volume is beneficial to biologists and researchers conducting work on the basic mechanisms involved in the regulation of diverse cellular activities.


Details

No. of pages:
332
Language:
English
Copyright:
© Academic Press 1980
Published:
Imprint:
Academic Press
eBook ISBN:
9781483217154

Ratings and Reviews


About the Editors

Bernard L. Horecker Editor

Earl R. Stadtman Editor