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List of Contributors
Brain Hexokinase, the Prototype Ambiquitous Enzyme
II. Subcellular Distribution of Hexokinase in Brain Homogenates
III. Cytoplasmic and Mitochondrial Forms of Brain Hexokinase
IV. Mitochondrial Hexokinase
V. Ambiquitous Behavior of Brain Hexokinase
VI. The Molecular Basis for the Specific Binding of Brain Hexokinase by the Outer Mitochondrial Membrane
VII. Hexokinase Activity as a Reflection of Glycolytic Capacity
VIII. Concluding Comments
Appendix: Ambiquitous Behavior—A Biological Phenomenon of General Significance?
Compartmentation of Hexokinase and Creatine Phosphokinase, Cellular Regulation, and Insulin Action
II. Experimental Evidence for Bound Hexokinase as a Compartmental Control Point
III. Bound Creatine Phosphokinase: Experimental Evidence for Compartmentation
IV. The Hexokinase-Mitochondrial Theory of Insulin Action and Hormonal Metabolic Control
Cytochrome c Methylation: Enzymology and Biologic Significance
I. Opening Remarks on Protein Methylation
II. Cytochrome c Methylation
III. Closing Remarks
Enzyme Organization in the Polyaromatic-Biosynthetic Pathway: The Arom Conjugate and Other Multienzyme Systems
II. The Polyaromatic-Biosynthetic Multienzyme System
III. Phylogenetic Aspects of Enzyme Organization in the Polyaromatic Pathway
IV. Concluding Remarks
Appendix: Enzyme Organization in Vivo: Some Thermodynamic-Kinetic Perspectives
Proteolysis in Bacterial Sporulation
II. The Proteolytic System of Bacilli
III. Evidence for a Role of Proteolysis in Sporulation
IV. Protein Turnover and Sporulation
V. Proteolytic Modulation of Gene Expression in Sporulation
VI. Inactivation and Modification of Proteins
VII. Proteolysis During Germination
VIII. Concluding Remarks
Cyclic Nucleotides in the Central Nervous System
II. Occurrence of Cyclic Nucleotide-Synthesizing and -Degrading Enzymes in the Mammalian Brain: Occurrence of Phosphorylation-Dephosphorylation Systems That Are Regulated by Cyclic Nucleotides: Regional and Subcellular Localization
III. Evidence for Neuronal or Glial Localization
IV. Evidence for Involvement of Cyclic Nucleotides in Synaptic Transmission: Electrophysiological Studies
V. Neurotransmitter Activation of Adenylate Cyclase
VI. Neurotransmitter-Mediated Increases in cGMP Levels
VII. Regulation of 3′5′-Cyclic Nucleotide Phosphodiesterases
VIII. Regulation of Cyclic Nucleotide-Dependent Protein Kinases
IX. Interactions of Ca2+ with the Cyclic Nucleotide-Dependent Processes
X. Considerations on the Regulatory Organization of the Cyclic Nucleotide Systems
Regulation of Oocyte Maturation
II. Oocytes as Target Cells for Steroid Hormones
III. Calcium Ion as a Positive Effector of Oocyte Maturation
IV. Regulation by Cyclic AMP
V. The Maturation-Promoting Factor and Its Regulation
VI. Current Model of Oocyte Maturation
Contents of Previous Volumes
Current Topics in Cellular Regulation, Volume 16 considers the advances in the general area of cellular regulation.
This book discusses the subcellular distribution of hexokinase in brain homogenates and experimental evidence for bound hexokinase as a compartmental control point. The enzymology and biologic significance of cytochrome c methylation, polyaromatic-biosynthetic multienzyme system, and proteolytic modulation of gene expression in sporulation are also elaborated. This text likewise covers the occurrence of cyclic nucleotide-synthesizing and -degrading enzymes in the mammalian brain and calcium ion as a positive effector of oocyte maturation.
This volume is beneficial to biologists and researchers conducting work on the basic mechanisms involved in the regulation of diverse cellular activities.
- No. of pages:
- © Academic Press 1980
- 28th June 1980
- Academic Press
- eBook ISBN:
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