Current Topics in Cellular Regulation

Current Topics in Cellular Regulation

1st Edition - December 28, 1978

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  • Editors: Bernard L. Horecker, Earl R. Stadtman
  • eBook ISBN: 9781483217130

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Current Topics in Cellular Regulation, Volume 14 reviews the advances in the general area of cellular regulation. This book discusses the mechanism and function of the C4 pathway, regulation of individual enzymes, inhibitors of isoleucine and valine biosynthesis, and patterns of derepression. The functions of 2,3-bisphosphoglycerate; 2,3-bisphosphoglycerate in erythrocytes during development; and regulation of glycogen synthetase activity are also elaborated. This publication likewise covers the substrate specificity of cAMP-dependent protein kinase, model systems of enzyme sequences, and posttranslational modifications in selected enzymes. This volume is a good source for biologists and researchers interested in the basic mechanisms involved in the regulation of diverse cellular activities.

Table of Contents

  • List of Contributors

    Regulation of Enzymes in C4 Photosynthesis

    I. Introduction

    II. Mechanism and Function of the C4 Pathway

    III. Regulation of Individual Enzymes

    IV. Other Aspects of Regulation


    Regulation of Isoleucine and Valine Biosynthesis

    I. Introduction

    II. Gene-Enzyme Relationship

    III. Specialized Plasmids

    IV. Regulation of the Metabolic Flow of Intermediates

    V. Patterns of Derepression

    VI. Inhibitors of Isoleucine and Valine Biosynthesis

    VII. The Corepressor Problem

    VIII. Gene Expression

    IX. Multiple Regulatory Mechanisms


    Functions of 2,3-Bisphosphoglycerate and Its Metabolism

    I. Introduction

    II. Historical Remarks

    III. Occurrence of 2,3-Bisphosphoglycerate

    IV. Functions of 2,3-Bisphosphoglycerate

    V Control of 2,3-Bisphosphoglycerate Metabolism

    VI. 2,3-Bisphosphoglycerate in Erythrocytes During Development


    The Role of Cyclic-AMP-Dependent Protein Kinase in the Regulation of Glycogen Metabolism in Mammalian Skeletal Muscle

    I. Introduction

    II. Discovery of the Glycogenolytic Cascade and cAMP-Dependent Protein Kinase

    III. The Regulation of Phosphorylase Kinase Activity

    IV. The Regulation of Glycogen Synthetase Activity

    V. The Regulation of Protein Phosphatase Activity

    VI. The Regulation of Protein Phosphatase 1 by Heat-Stable Inhibitor Proteins

    VII. The Substrate Specificity of cAMP-Dependent Protein Kinase

    VIII. The Substrate Specificity of Protein Phosphatases 1 and 2

    IX. The Components of the Protein-Glycogen Complex


    Immobilized Model Systems of Enzyme Sequences

    I. Introduction

    II. Naturally Occurring Systems of Enzyme Sequences

    III. Model Systems of Enzyme Sequences

    IV. On the Relevance of Immobilized Enzyme Sequences as Biological Models for Naturally Occurring Systems (Microenvironmental Compartmentation)

    V. Practical Applications of Immobilized Enzyme Sequences


    Posttranslational Modifications of Enzymes

    I. Introduction

    II. Alterations of Enzymes in Selected Systems

    III. Posttranslational Modifications in Selected Enzymes

    IV. General Mechanisms

    V. Conclusion

    VI. Summary

    List of Abbreviations


    Subject Index

    Contents of Previous Volumes

Product details

  • No. of pages: 316
  • Language: English
  • Copyright: © Academic Press 1978
  • Published: December 28, 1978
  • Imprint: Academic Press
  • eBook ISBN: 9781483217130

About the Editors

Bernard L. Horecker

Earl R. Stadtman

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