Current Topics in Cellular Regulation - 1st Edition - ISBN: 9780121528041, 9781483217031

Current Topics in Cellular Regulation, Volume 4

1st Edition

Editors: Bernard L. Horecker Earl R. Stadtman
eBook ISBN: 9781483217031
Imprint: Academic Press
Published Date: 28th October 1971
Page Count: 282
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Table of Contents


List of Contributors


Preface


Contents of Previous Volumes


The Regulation of Arginine Metabolism in Saccharomyces Cerevisiae: Exclusion Mechanisms


I. Introduction


II. Inhibition of Ornithine Transcarbamylase by Epiarginase


III. Common Genetic Elements in the Control of Biosynthetic and Degradative Enzyme Synthesis


IV. Conclusions


References


The Lac Repressor


I. Introduction


II. The Repressor Protein


III. Inducer Binding


IV. Operator Binding


V. The Mechanism of Induction


VI. The Operator


VII. Positive Control of the Lac Operon


VIII. The Mode of Action of the Lac Repressor


IX. Generalization


References


L-Glutamate Dehydrogenases


I. Introduction


II. Physical and Chemical Properties of Glutamate Dehydrogenases


III. The Catalytic Reaction


IV. Purine Nucleotide Effect


V. Other Modifiers


VI. Chemical Modification


VII. Metabolic Role of Glutamate Dehydrogenases


VIII. Conclusion


References


Regulation of Fatty Acid Biosynthesis


I. Introduction


II. Acetyl-CoA Carboxylase


III. Fatty Acid Synthetase


References


Kinetic Analysis of Allosteric Enzymes


I. Objective and Limits of the Review


II. Specific Examples


III. Conclusion


References


Phosphorylase and the Control of Glycogen Degradation


I. Introduction


II. Structure, Activity, and Interconversion of Phosphorylase


III. State of Activity of Phosphorylase in Striated Muscle


IV. Phosphorylase Kinase


V. Phosphorylase Phosphatase Structure and Enzymatic


Description

Current Topics in Cellular Regulation, Volume 4 presents the fundamental mechanisms involved in the regulation of diverse cellular activities, including cellular differentiation, intermediary metabolism, and the transfer of genetic information. This book provides information pertinent to the various aspects of cellular regulation.

Organized into six chapters, this volume begins with an overview of the activity of ornithine transcarbamylase that catalyzes the condensation of carbamyl phosphate with ornithine. This text then presents and discusses the in vitro data that are available on the molecular interactions that govern the expression of lactose (lac) operon. Other chapters consider the bovine liver, which has been characterized in terms of molecular and kinetic characteristics. This book discusses as well the de novo synthesis of saturated fatty acids, which is catalyzed by two enzyme systems. The final chapter deals with the factors leading to glycogenolysis as it occurs in mammalian skeletal muscle.

This book is a valuable resource for biologists and biochemists.


Details

No. of pages:
282
Language:
English
Copyright:
© Academic Press 1971
Published:
Imprint:
Academic Press
eBook ISBN:
9781483217031

Ratings and Reviews


About the Editors

Bernard L. Horecker Editor

Earl R. Stadtman Editor