Current State of the Art in Spinal Trauma, An Issue of Neurosurgery Clinics of North America

1st Edition, Volume 32-3 - June 8, 2021
Editor: John Hurlbert
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 8 1 0 5 8 - 6
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 8 1 0 5 9 - 3

This issue of Neurosurgery Clinics, guest edited by Dr. John Hurlbert, is devoted to Current State of the Art in Spinal Cord Injury. This is one of four issues selected each year… Read more

Current State of the Art in Spinal Trauma, An Issue of Neurosurgery Clinics of North America

Purchase options

Info / Buy

LIMITED OFFER

Save 50% on book bundles

Immediately download your ebook while waiting for your print delivery. No promo code is needed.

Institutional subscription on ScienceDirect

Request a sales quote

This issue of Neurosurgery Clinics, guest edited by Dr. John Hurlbert, is devoted to Current State of the Art in Spinal Cord Injury. This is one of four issues selected each year by the series Consulting Editors, Russell R. Lonser and Daniel K. Resnick. Articles in this issue are dedicated to basics of spinal cord injury and emerging therapy and include topics such as: Pathophysiology of spinal cord injury, Natural history of spinal cord injury, Diagnostic imaging in spinal cord injury, Spinal cord injury clinical assessment tools, Spinal cord injury management on the front line, Central Cord Syndrome redefined, Compartment Syndrome, Hypothermia, Pharmaceutical, Regeneration, and Neural interfacing and modulation.

Cover image
Title page
Table of Contents
Copyright
Contributors
Forthcoming Issues
Preface
Section I: Basics of SCI
Pathophysiology of Spinal Cord Injury
Key points
Introduction
Phases of injury
Molecular and chemical mediators of spinal cord injury pathogenesis
Alterations in neural circuitry
Emerging concepts in the study of spinal cord injury pathogenesis
Summary
Clinics care points
The Natural History of Spinal Cord Injury
Key points
Introduction
The natural history of spinal cord injury
Complete spinal cord injuries
Incomplete spinal cord injuries
Recovery of walking ability after spinal cord injury
Neuromodulation after spinal cord injury
Future directions
Summary
Clinics care points
Diagnostic Imaging in Spinal Cord Injury
Key points
Introduction
Imaging in acute spinal cord injury diagnosis
Perfusion imaging
Summary
Clinics care points
Spinal Cord Injury Clinical Classification Systems: What Is Available and a Proposed Alternative
Key points
Introduction
A tool for next-generation spinal cord injury assessment
Summary
Clinics care points
Spinal Cord Injury Management on the Front Line: ABCs of Spinal Cord Injury Treatment Based on American Association of Neurological Surgeons/Congress of Neurological Surgeons Guidelines and Common Sense
Key points
Introduction
Airway
Breathing
Circulation
Summary of the ABCs
Closed reduction
Prereduction MRI
Timing of surgical management
Summary
Clinics care points
Central Cord Syndrome Redefined
Key points
Introduction
Epidemiology
Pathophysiology
Management
Central cord syndrome redefined
Summary
Clinics care points
Section II: Emerging Therapies
Acute, Severe Traumatic Spinal Cord Injury: Monitoring from the Injury Site and Expansion Duraplasty
Introduction
History
Lessons from traumatic brain injury
Monitoring from the injury site in spinal cord injury
Optimizing cord perfusion
Microdialysis monitoring
Injury site monitoring and outcome
Expansion duraplasty
Summary
Clinics care points
Hypothermia for Acute Spinal Cord Injury
Key points
Introduction
History of hypothermia in humans
Mechanisms of action of hypothermia for neuroprotection
Animal evidence for hypothermia after spinal cord injury
Human evidence for hypothermia after spinal cord injury
Complications of therapeutic hypothermia and rewarming
Summary
Clinics care points
Pharmacologic and Cell-Based Therapies for Acute Spinal Cord Injury
Key points
Introduction
Pharmacologic therapies
Biodegradable polymers as scaffolds
Cell therapies
Summary
Clinics care points
Targeting Central Nervous System Regeneration with Cell Type Specificity
Key points
Introduction
Pathology: cellular and molecular responses to spinal cord injury
Cell reactivity: astrocyte scar-border formation
Cell reactivity: fibrotic scar formation
Neuronal heterogeneity: lessons from the optic nerve
Neuronal heterogeneity: application to spinal cord injury
Summary
Clinics care points
Brain-Computer Interface, Neuromodulation, and Neurorehabilitation Strategies for Spinal Cord Injury
Key points
Introduction
Brain-computer interfacing
Neurorehabilitation
Functional electrical stimulation
High-intensity, high-volume targeted training
Exoskeleton use in spinal cord injury
Summary
Clinics care points