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Current Developments in Biotechnology and Bioengineering - 1st Edition - ISBN: 9780444636683, 9780444636799

Current Developments in Biotechnology and Bioengineering

1st Edition

Foundations of Biotechnology and Bioengineering

Editors: Ashok Pandey Jose Antonio Teixeira
Hardcover ISBN: 9780444636683
eBook ISBN: 9780444636799
Imprint: Elsevier
Published Date: 15th September 2016
Page Count: 296
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Current Developments in Biotechnology and Bioengineering: Foundations of Biotechnology and Bioengineering is a package of nine books that compile the latest ideas from across the entire arena of biotechnology and bioengineering. This volume focuses on the underlying principles of biochemistry, microbiology, fermentation technology, and chemical engineering as interdisciplinary themes, constructing the foundation of biotechnology and bioengineering.

Key Features

  • Provides state-of-art information on basics and fundamental principles of biotechnology and bioengineering
  • Supports the education and understanding of biotechnology education and R&D
  • Contains advanced content for researchers engaged in bioengineering research


Postgraduate and PhD students and researchers in academia, government and corporate research in the area of bioengineering/biochemical engineering, biomedical/biological engineering and industrial biotechnology

Table of Contents

  • List of Contributors
  • About the Editors
  • Preface
  • 1. Basic Microbiology
    • 1.1. Introduction
    • 1.2. Microbial Diversity and Systematics
    • 1.3. Microbial Physiology and Metabolism
    • 1.4. Different Branches and Scope of Microbiology
    • 1.5. Microbial Reproduction
    • 1.6. Culturable and Nonculturable Microbes
    • 1.7. Microbial Genomics and Metabolomics
    • 1.8. Economic Significance of Microbes
    • 1.9. Conclusions and Perspectives
  • 2. Basic Biochemistry
    • 2.1. Introduction
    • 2.2. Structure and Function of Proteins
    • 2.3. Enzymes
    • 2.4. Physicochemical Properties of Mono-, Oligo-, and Polysaccharides
    • 2.5. Characteristics and Properties of Lipids
    • 2.6. Nucleic Acids
    • 2.7. Energetics
  • 3. Fundamentals of Molecular Biology
    • 3.1. Introduction
    • 3.2. DNA Replication
    • 3.3. Transcription
    • 3.4. Regulation of Transcription: The Operon
    • 3.5. DNA Damage and Repair
    • 3.6. Recombination
    • 3.7. Transposable Elements
    • 3.8. Plasmids
    • 3.9. Horizontal Gene Transfer and Genome Evolution
    • 3.10. Blotting Techniques
    • 3.11. Polymerase Chain Reaction
    • 3.12. DNA Sequencing
    • 3.13. Conclusions and Perspectives
  • 4. Principles of Genetic Engineering
    • 4.1. Introduction
    • 4.2. Basic Techniques
    • 4.3. Recombinant DNA Technology
    • 4.4. Genetic Engineering in Industrial Biotechnology and Bioengineering
    • 4.5. Conclusions and Perspectives
  • 5. Principles of Metabolic Engineering
    • 5.1. Introduction
    • 5.2. Metabolic Pathway Flux Map
    • 5.3. Basis of Metabolic Models and Flux Analysis
    • 5.4. Network Simplifications
    • 5.5. Concept of Reaction Stoichiometry in Flux Analysis
    • 5.6. Flux Estimation in Underdetermined Systems
    • 5.7. Metabolic Control Analysis
    • 5.8. Conclusion and Perspectives
  • 6. Fundamentals of Bio-reaction Engineering
    • 6.1. Introduction
    • 6.2. Enzyme Kinetics
    • 6.3. Cell Growth Kinetics
    • 6.4. Main Bioreactor Types
    • 6.5. Bioreactor Modes of Operation
    • 6.6. Gas–Liquid Mass Transfer
    • 6.7. Bioprocess Monitoring and Control
    • 6.8. Conclusions and Perspectives
  • 7. Fundamentals of Biological Separation Processes
    • 7.1. Introduction
    • 7.2. General Considerations
    • 7.3. Upstream Processing
    • 7.4. Cell Harvest
    • 7.5. Primary Recovery
    • 7.6. Intermediate Purification
    • 7.7. Final Purification
    • 7.8. Conclusions and Perspectives
  • 8. Synthetic Biology: Perspectives in Industrial Biotechnology
    • 8.1. Introduction
    • 8.2. Synthetic Biology Methods and Tools
    • 8.3. Synthetic Biology Applications
    • 8.4. Concerns About Synthetic Biology
    • 8.5. Summary and Conclusion
  • Index


No. of pages:
© Elsevier 2017
15th September 2016
Hardcover ISBN:
eBook ISBN:

About the Editors

Ashok Pandey

Ashok Pandey

Professor Ashok Pandey is currently Distinguished Scientist at the Centre for Innovation and Translational Research, CSIR-Indian Institute of Toxicology Research, Lucknow, India and Executive Director (Honorary) at the Centre for Energy and Environmental Sustainability – India. Formerly, he was Eminent Scientist at the Center of Innovative and Applied Bioprocessing, Mohali and Chief Scientist & Head of Biotechnology Division and Centre for Biofuels at CSIR’s National Institute for Interdisciplinary Science and Technology, Trivandrum. His major research and technological development interests are industrial & environmental biotechnology and energy biosciences, focusing on biomass to biofuels & chemicals, waste to wealth & energy, industrial enzymes, etc. Professor Pandey is Adjunct/Visiting Professor/Scientist in universities in France, Brazil, Canada, China, Korea, South Africa, and Switzerland and also in several universities several in India. He has ~ 1375 publications/communications, which include 16 patents, 83 books, ~ 700 papers and book chapters, etc with h index of 97 and >43,000 citations (Goggle scholar). He has transferred several technologies to industries and has done industrial consultancy for about a dozen projects for Indian/international industries. Professor Pandey is the recipient of many national and international awards and honours, which include Highest Cited Researcher (Top 1% in the world; Top 10 among in India), Clarivate Analytics, Web of Science (2019); Yonsei Outstanding Scholar, Yonsei University, Seoul, Korea (2019), Highest Cited Researcher (Top 1% in the world; Top 10 among in India), Clarivate Analytics, Web of Science (2018); Life-Time Achievement Award from the Biotech Research Society, India (2018); Life-Time Achievement Award from Venus International Research Awards (2018), Most Outstanding Researcher Award from Career360 (2018), Life-Time Achievement Award from the International Society for Energy, Environment and Sustainability (2017); Academician of European Academy of Sciences and Arts, Austria (2015); Honorary Doctorate degree from Univesite Blaise Pascal, France (2007); Thomson Scientific India Citation Laureate Award, USA (2006); UNESCO Professor (2000); Raman Research Fellowship Award, CSIR (1995); GBF, Germany and CNRS, France Fellowships (1992) and Young Scientist Award (1989), etc. He is Fellow of various academies, which include Royal Society of Biology, UK (2016); International Society for Energy, Environment and Sustainability (2016); National Academy of Sciences, India (2012); Association of Microbiologists of India (2008), International Organization of Biotechnology and Bioengineering (2007) and the Biotech Research Society, India (2005). Professor Pandey is Founder President of the Biotech Research Society, India (; Founder & International Coordinator of International Forum on Industrial Bioprocesses, France (, Chairman of the International Society for Energy, Environment & Sustainability (, Editor-in-chief of Bioresource Technology (, Honorary Executive Advisor of Journal of Water Sustainability ( and Journal of Energy and Environmental Sustainability (, Subject Editor of Proceedings of National Academy of Sciences, India ( and editorial board member of several international and Indian journals

Affiliations and Expertise

Distinguished Scientist, Centre for Innovation and Translational Research, CSIR-Indian Institute of Toxicology Research, Lucknow, India

Jose Antonio Teixeira

José Teixeira ( Laboratório Associado - Institute for Biotechnology and Bioengineering, Centre for Biological Engineering, Universidade of Minho, Campus de Gualtar

4710-057, Braga - Portugal, E-mail:

is a Full Professor and currently the Head of Biological Engineering Research Center (CEB) of the Engineering School of Minho University. CEB is responsible for scientific research and advanced formation in Biological and Chemical Engineering. He got a Chemical Engineering degree from University of Porto in 1980, place where he also obtained his PhD in 1988. Jose Teixeira research activities have been focused on two main topics: bioprocess development - bioreactor development and characterization; yeast physiology and bio-separation processes, bio-surfactants production for biomedical and MEOR applications; and food technology. He was scientific coordinator in 32 research projects, 7 of them EU financed, He was also the supervisor of 31 PhDs and 16 pos-doc researcher. He has authored 350 peer reviewed papers and is co-editor of the books “Reactores Biológicos-Fundamentos e Aplicações” (in Portuguese) and Engineering Aspects of Milk and Dairy Products.

Affiliations and Expertise

Full Professor and Head of the Biological Engineering Research Center (CEB), School of Engineering, University of Minho, Portugal

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