Current Concepts in Kinin Research

Current Concepts in Kinin Research

Proceedings of the Satellite Symposium of the 7th International Congress of Pharmacology, Paris, 22 July 1978

1st Edition - January 1, 1979

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  • Editors: Gert L. Haberland, Ulla Hamberg
  • eBook ISBN: 9781483159096

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Current Concepts in Kinin Research contains the proceedings of the Satellite Symposium of the 7th International Congress of Pharmacology held in Paris on July 22, 1978. The book is organized into four parts. Part I explains the functions and mechanisms of the kinin system. Part II focuses on kallikreins and the methods of their determination. Part III describes the intrinsic blood clotting and plasma kinin formation. The last part deals with the characterization of plasma kininogens.

Table of Contents

  • Contents

    1. Functions and Mechanisms of the Kinin System


    Opening Remarks

    The Role of Kinin System in Male Fertility

    Kinin Involvement in Oestrogen-induced Hyperaemia in the Rat

    Kallikreins - Their Possible Biological Significance as Widely Distributed Serine Proteases

    The Mechanism of Action of Bradykinin on the Isolated Rat Uterus. Involvement of Prostaglandins?

    Bile may be a Stimulus for Activation of Duodenal Kallikrein during Digestion

    Interactions of Kinins with Amines and Peptides in the Microcirculation

    Plasmakinin System in Alloxan Diabetic Rats

    Large-scale Preparation of N-carboxypeptidase (Kininase I) as By-product of Routine Fractionation

    Neutral Proteases from Granulocytes and their Inhibitors

    2. Kallikreins and Methods of Determination

    The Role of Kallikrein in the Pathogenesis of African Trypanosomiasis

    Cl Inhibitor: the Main Inhibitor of Human Plasma Kallikrein

    Purification of Kallikrein in Human Pancreatic Juice, Immunological and Inhibition Studies

    Studies on the Physiological Function of Glandular Kallikrein by Radioimmunoassay

    Comparison of Kinin Release and Blood Pressure Activity of Porcine Pancreatic, Submandibular, and Urinary Kallikrein

    Isolation and Determination of Human Urinary Kallikrein

    Some Properties of Human Urinary Kallikrein obtained through Scaled-up Purification

    A New Assay for Urinary Kallikrein

    Studies on the Activation of the Pre-kininogenin-Kininogenin (Pre-kallikrein-Kallikrein) System by Sulfated Polysaccharides and Kaolin

    Fragmentation of Rabbit Low Molecular Weight Kininogenin by Pig Pancreatic Kallikrein

    3. Intrinsic Blood Clotting and Plasma Kinin Formation

    The Use of Chromogenic Substrates for the Determination of Kallikrein and Other Serine Proteases in Plasma and Synovial Fluid in Man

    The Evaluation of Hog Pancreatic Kininogenase and Methods of Measurement

    Bradykinin Radioimmunoassay in Plasma Kininase Determination

    Kinin and Myocardial Infarction: Effect of Trasylol on the Plasma Prekallikrein and Kallikrein Inhibitor

    Immunoreactive Kininogen in Acute Myocardial Infarction Determined by Single Radial Immunodiffusion using Monospecific Anti-Kininogen Serum

    4. Characterization of Plasma Kininogens — Kinin Potentiation

    Structure-Function Relationships of Human High MW Kininogen Related to Contact Activation of Plasma (Abstract)

    Heterogeneity of Native and Isolated Human Plasma Kininogens

    A Rapid Method for the Preparation of Plasma Alpha2 SH Glycoprotein: Use of the Zinc-Chelate Affinity Chromatography as an Intermediary Step

    Interaction of Smooth Muscle Endogenous Prostaglandins with Kinins-Potentiators

    Effect of Stretching of the Guinea-pig Ileum Upon its Response to Bradykinin and to Bradykinin-potentiating Peptides

    Antagonism of the Bradykinin Induced Contractile Response of Isolated Smooth Muscle Preparations by Low Molecular Weight Synthetic Chromogenic Peptide Substrates for Serine Proteases

    Plasma Kininogen, Plasma Renin Activity and Blood Pressure Responses in Sodium-induced Renal Hypertension in Rats

    The Effect of Aprotinin on Luteolysis and Uterine Motility in Late Pregnancy and Parturition in Rats

    The Kinin System and Non-adrenergic, Non-cholinergic (NANC) Nerves in the Colon

    Improved Methods to Assay Contact Activation

    Concluding Remarks


Product details

  • No. of pages: 294
  • Language: English
  • Copyright: © Pergamon 1979
  • Published: January 1, 1979
  • Imprint: Pergamon
  • eBook ISBN: 9781483159096

About the Editors

Gert L. Haberland

Ulla Hamberg

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