Criteria (Dose/Effect Relationships) for Organochlorine Pesticides - 1st Edition - ISBN: 9780080234410, 9781483137506

Criteria (Dose/Effect Relationships) for Organochlorine Pesticides

1st Edition

Report of a Working Group of Experts Prepared for the Commission of the European Communities, Directorate-General for Employment and Social Affairs, Health and Safety Directorate

Authors: M. Mercier
eBook ISBN: 9781483137506
Imprint: Pergamon
Published Date: 1st January 1981
Page Count: 398
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Description

Criteria (Dose/Effect Relationships) for Organochlorine Pesticides presents the effect of organochlorine compounds on the immunological processes. This book deals with several organochlorine pesticides.

Organized into 15 chapters, this book begins with an overview of the properties and toxicology of dichlorodiphenyl trichloroethane (DDT), a potent non-systemic stomach and contact insecticide of high persistence on solid surface. This text then examines the absorption, metabolism, and excretion of lindane in laboratory animals and in humans as well. Other chapters consider the studies on the carcinogenic potential as well as the mutagenic effects of dieldrin. This book discusses as well the metabolism and pharmacokinetics of endrin, which is a non-systemic and persistent insecticide used primarily on field crops. The final chapter deals with the need for further evaluation of any possible long-term risks to humans from the production and use of the technical product.

This book is a valuable resource for agriculturists and research workers.

Table of Contents


Preface

Acknowledgements, List of Experts

Chapter I DDT

Chemical and Physical Properties

Studies in Laboratory Animals

Toxic Effects in Animals

Subchronic and Chronic Effects

Mutagenic Effects

Carcinogenic Effects

Effects on Reproduction

Effects on Man

Chapter II Lindane (Gamma-HCH)

Physical and Chemical Properties

Studies in Laboratory Animals

Toxic Effects in Animals

Subchronic and Chronic Effects

Mutagenic Effects

Carcinogenic Effects

Effects on Reproduction

Effects on Man

Conclusions

Chapter III Aldrin

Chemical and Physical Properties

Studies in Laboratory Animals

Toxic Effects in Animals

Subchronic and Chronic Effects

Mutagenic Effects

Carcinogenic Effects

Effects on Reproduction

Effects on Man

Conclusions

Chapter IV Dieldrin

Chemical and Physical Properties

Studies in Laboratory Animals

Toxic Effects in Animals

Subchronic and Chronic Effects

Mutagenic Effects

Carcinogenic Effects

Effects on Reproduction

Effects on Man

Conclusions

Chapter V Endrin

Chemical and Physical Properties

Studies on Laboratory Animals

Subchronic and Chronic Effects

Effects on Reproduction

Mutagenic Effects

Carcinogenic Effects

Effects on Man

Conclusions

Chapter VI Heptachlor

Chemical and Physical Properties

Studies on Laboratory Animals

Toxic Effects in Animals

Subchronic and Chronic Effects

Carcinogenic Effects

Embryotoxic Effects

Effects on Man

Conclusions

Chapter VII Chlordane

Chemical and Physical Properties

Studies in Laboratory Animals

Toxic Effects in Animals

Subchronic and Chronic Effects

Carcinogenic Effects

Effects on Reproduction

Effects on Man

Conclusions

Chapter VIII Hexachlorobenzene

Chemical and Physical Properties

Studies on Laboratory Animals

Toxic Effects in Animals

Subchronic and Chronic Effects

Mutagenic Effects

Carcinogenic Effects

Reproductive Effects

Embryotoxic Effects

Effects on Man

Residues in Food

Conclusions

Chapter IX Pentachlorophenol

Chemical and Physical Properties

Studies on Laboratory Animals

Subchronic and Chronic Effects

Mutagenic Effects

Carcinogenic Effects

Embryotoxic Effects

Effects on Man

Conclusions

Chapter X Methoxychlor

Chemical and Physical Properties

Studies on Laboratory Animals

Subchronic and Chronic Effects

Mutagenic Effects

Carcinogenic Fffects

Embryotoxic Effects

Effects on Man

Residues in Food

Conclusions

Chapter XI Endosulfan

Chemical and Physical Properties

Studies on Laboratory Animals

Toxic Effects in Animals

Subchronic and Chronic Effects

Mutagenic Effects

Carcinogenic Effects

Embryotoxic Effects

Effects on Man

Residues in Food

Conclusions

Chapter XII Quintozene/PCNB

Chemical and Physical Properties

Studies on Laboratory Animals

Toxic Effects on Animals

Subchronic and Chronic Effects

Mutagenic Effects

Carcinogenic Effects

Embryotoxic Effects

Effects on Man

Residues in Food

Conclusions

Chapter XIII MCPA, MCPB, Mecoprop and Dichlorprop

Chemical and Physical Properties

Studies on Laboratory Animals

Toxic Effects on Animals

Subchronic and Chronic Effects

Dichlorprop

Mutagenic Effects

Embryotoxic Effects

Effects on Man

Conclusions

Chapter XIV 2,4-D

Chemical atid Physical Properties

Studies on Laboratory Animals

Toxic Effects on Animals

Subchronic and Chronic Effects

Mutagenic Effects

Carcinogenic Effects

Embryotoxic Effects

Effects on Man

Conclusions

Chapter XV 2,4,5-T

Chemical and Physical Properties

Studies on Laboratory Animals

Toxic Effects on Animals

Subchronic and Chronic Effects

Mutagenic Effects

Carcinogenic Effects

Embryotoxic Effects

Observations in Man

Conclusions

Bibliography

Appendix: 2,3,7,8-Tetrachlorodibenzop-Dioxin

Details

No. of pages:
398
Language:
English
Copyright:
© Pergamon 1981
Published:
Imprint:
Pergamon
eBook ISBN:
9781483137506

About the Author

M. Mercier

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