
CRISPR Genome Surgery in Stem Cells and Disease Tissues
Description
Key Features
- Provides a thorough review of CRISPR-Cas9, from discovery to therapy
- Covers the latest advances in gene editing and its translational applications to various diseases
- Written by global leaders in the fields of gene editing and stem cell therapy
Readership
Scientists involved in stem cell engineering and gene editing, and individuals of any medical subspecialty
Table of Contents
1. History of CRISPR
2. Different Kinds of CRISPR (SpCas9, CjCas9, CaCas9, etc.)
3. Genome engineering in iPSC cells
4. CRISPR manipulations in stem cell lines for neurological diseases
5. Gene editing for the cornea
6. CRISPR screening for eye diseases
7. Employing Non-homologous End Joining and Homology-directed Repair for Treatment of Leber Congenital Amaurosis and Retinal Degeneration
8. Ethics of Gene Editing in Human Stem Cells
9. sGRNA
10. CRISPR vs ZFN/TALEN
Product details
- No. of pages: 136
- Language: English
- Copyright: © Academic Press 2021
- Published: October 19, 2021
- Imprint: Academic Press
- eBook ISBN: 9780128178775
- Paperback ISBN: 9780128178768
About the Editor
Stephen Tsang
Affiliations and Expertise
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