Taking a history. Examination of the patient. The clerking. Chest pain. Shortness of breath. Palpitations. Cough and haemopytsis. Pyrexia of unknown origin. Dyspepsia. Haematemesis and melaena. Change in bowel habit. Weight loss. Jaundice. Abdominal pain. Urinary symptoms. Haematuria and proteinuria. Hypertension. Headache and facial pain. Joint disease. Back pain. Skin lesions and rash. Loss of consciousness. Confusional states. Stroke and transient ischaemic attack. Lymphadenopathy and splenomegaly. Sensory and motor neurological deficits. Vertigo and dizziness. Excessive bruising and bleeding. Anaemia. Cardiovascular system. Respiratory disease. Gastrointestinal and liver disease. Genitourinary system. Central nervous system. Metabolic and endocrine disorders. Musculoskeletal and skin disorders. Haematological disorders. Infectious diseases. Drug overdose and abuse. Self-assessment.