Coronaviruses, Volume 96

• In Memoriam
• Preface
• Chapter One: Supramolecular Architecture of the Coronavirus Particle
  • Abstract
  • 1 Introduction
  • 2 Virion Structure and Durability
  • 3 Viral Proteins in Assembly and Fusion
  • 4 Evolution of the Structural Proteins
• Chapter Two: Coronavirus Spike Protein and Tropism Changes
  • Abstract
  • 1 Introduction
  • 2 Structure of the Coronavirus S Protein
  • 3 Spike–Receptor Interactions
  • 4 S Protein Proteolytic Cleavage and Conformational Changes
  • 5 Tropism Changes Associated with S Protein Mutations
  • 6 Concluding Remarks
  • Acknowledgments
• Chapter Three: The Nonstructural Proteins Directing Coronavirus RNA Synthesis and Processing
  • Abstract
  • 1 Introduction
  • 2 Coronavirus nsp7–10: Small but Critical Regulatory Subunits?
  • 3 Coronavirus nsp12: A Multidomain RNA Polymerase
  • 4 Coronavirus nsp13: A Multifunctional and Highly Conserved Helicase Subunit
  • 5 The Coronavirus Capping Machinery: nsp10–13–14–16
  • 6 Coronavirus nsp14 ExoN: Key to a Unique Mismatch Repair Mechanism That Promotes Fidelity
  • 7 Coronavirus nsp15: A Remarkable Endoribonuclease with Elusive Functions
  • 8 Summary and Future Perspectives
  • Acknowledgments
• Chapter Four: Coronavirus cis-Acting RNA Elements
  • Abstract
  • 1 Introduction
  • 2 Coronavirus Genome Replication and Transcription
  • 3 Coronavirus cis-Acting RNA Elements
  • 4 RNA Elements Involved in Coronavirus Genome Packaging
  • 5 Possible Roles of Cellular Proteins in Coronavirus Replication
  • 6 Conclusions and Outlook
  • Acknowledgments
• Chapter Five: Viral and Cellular mRNA Translation in Coronavirus-Infected Cells
  • Abstract
  • 1 Introduction
  • 2 Mechanisms and Control of Translation of Coronavirus mRNAs
  • 3 Host and Viral Factors That Regulate Coronavirus mRNA Translation
  • 4 Coronavirus-Mediated Control of Host Translation
  • 5 Concluding Remarks
  • Acknowledgments
• Chapter Six: Feline Coronaviruses: Pathogenesis of Feline Infectious Peritonitis
  • Abstract
  • 1 Feline Coronaviruses
  • 2 Infection with Feline Coronaviruses
  • 3 Molecular Pathogenesis of FIP
  • 4 Reverse Genetics of Feline Coronaviruses
  • 5 Perspectives
• Chapter Seven: Interaction of SARS and MERS Coronaviruses with the Antiviral Interferon Response
  • Abstract
  • 1 Introduction
  • 2 The Coronavirus Genome
  • 3 The Type I IFN System
  • 4 Antiviral Action of IFNs Against Human Coronaviruses
  • 5 Evasion Strategies of Coronaviruses
  • 6 Conclusions and Outlook
  • Acknowledgments
• Chapter Eight: Molecular Basis of Coronavirus Virulence and Vaccine Development
  • Abstract
  • 1 Introduction
  • 2 Subunit, Inactivated, and Vectored Vaccines
  • 3 Live-Attenuated Vaccines
  • 4 Vaccine Biosafety
  • 5 Coronavirus Antiviral Selection
  • 6 Conclusions
  • Acknowledgments
• Index

Coronaviruses, the latest volume in the Advances in Virus Research series first published in 1953, covers a diverse range of in-depth reviews, providing a valuable overview of the field. This series is a valuable resource for virologists, microbiologists, immunologists, molecular biologists, pathologists, and plant researchers.

• Contains contributions from leading authorities in virus research
• Provides comprehensive reviews for general and specialist use
• Presents the first and longest-running review series in virology

Professional virologists, from professors to graduate students, microbiologists and infectious diseases specialists