Coronary Artery Disease, An Issue of Cardiology Clinics

1st Edition, Volume 38-4 - October 20, 2020
Editor: Alberto Polimeni
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 7 7 7 0 9 - 4
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 7 7 7 1 0 - 0

This issue of Cardiology Clinics will cover Coronary Artery Disease. Curated by Dr. Alberto Polimeni, this issue will explore topics in the field that are relevant for practicing… Read more

Coronary Artery Disease, An Issue of Cardiology Clinics

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This issue of Cardiology Clinics will cover Coronary Artery Disease. Curated by Dr. Alberto Polimeni, this issue will explore topics in the field that are relevant for practicing clinicians. This issue is one of four selected each year by the series editorial board: Jamil A. Aboulhosn, David M. Shavelle, Terrence D. Welch, and Audrey H. Wu. The volume will include articles on: High sensitivity troponins in acute coronary syndromes, High bleeding risk patient with CAD, Complete revascularization in chronic coronary syndrome, Patient selection for protected PCI, Clinical applications of echo strain imaging in coronary artery disease, Mechanical circulatory support for cardiogenic shock, Impact of NO donors on atherogenesis and atherosclerosis progression, Non-invasive Imaging risk stratification for CAD, Antithrombotic therapy for patients with atrial fibrillation undergoing percutaneous coronary intervention, No-Reflow phenomenon, Coronary physiology assessment for the diagnosis and treatment of CAD, Bioresorbable coronary scaffold technologies, Non-coding RNAs in coronary artery disease, New advances in the treatment of severe coronary artery calcifications, and Refractory angina pectoris.

Cover image
Title page
Table of Contents
Copyright
Contributors
Cardiology Clinics
Preface
State of the Art—High-Sensitivity Troponins in Acute Coronary Syndromes
Key points
Introduction
Definitions
Discussion
Summary
Clinics care points
The High Bleeding Risk Patient with Coronary Artery Disease
Key points
Introduction
Prognostic impact of bleeding events after percutaneous coronary intervention or acute coronary syndrome
High bleeding risk definition and risk stratification
Dual antiplatelet therapy duration individualization among patients at high bleeding risk
Summary
Complete Revascularization in Acute and Chronic Coronary Syndrome
Key points
Introduction
Complete revascularization in acute coronary syndrome
Complete revascularization in chronic coronary syndrome
Summary
Patient Selection for Protected Percutaneous Coronary Intervention: Who Benefits the Most?
Key points
Introduction
Definition of protected percutaneous coronary intervention
Hemodynamic impact of mechanical circulatory support devices
Clinical criteria for patient selection for protected percutaneous coronary intervention
Procedure-related criteria for patient selection for protected percutaneous coronary intervention
Algorithm and scoring system for patient selection for protected percutaneous coronary intervention
Summary
Echocardiographic Strain Imaging in Coronary Artery Disease: The Added Value of a Quantitative Approach
Key points
Introduction
Left ventricular strain and myocardial ischemic process
Speckle tracking echocardiography in patients with stable angina and acute coronary syndrome
Early systolic lengthening and postsystolic shortening of left ventricular segments
Right ventricle function
Left atrial function
Summary
Currently Available Options for Mechanical Circulatory Support for the Management of Cardiogenic Shock
Key points
Introduction
Forms of percutaneous mechanical circulatory support for left ventricular support
Impella
TandemHeart
Peripherally cannulated extracorporeal membrane oxygenation
Percutaneous mechanical circulatory support for right ventricular support
Selecting the appropriate mechanical circulatory support device
Multidisciplinary shock teams and shock protocols
Mechanical circulatory support devices in development
Summary
Noninvasive Imaging Risk Stratification with Computed Tomography Angiography for Coronary Artery Disease
Key points
Background
Current indications for coronary computed tomography angiography: the definition of clinical likelihood
Coronary computed tomography angiography in suspect obstructive coronary artery disease
Coronary computed tomography angiography in special settings
Summary
Antithrombotic Therapy in Patients with Atrial Fibrillation Undergoing Percutaneous Coronary Intervention
Key points
Introduction
Antithrombotic strategies in patients undergoing percutaneous coronary intervention without an indication for oral anticoagulation
Antithrombotic therapies in patients undergoing percutaneous coronary intervention with an indication for oral anticoagulation
Antithrombotic management of patients with atrial fibrillation after percutaneous coronary intervention: guideline and consensus recommendations
Summary
State of the Art: No-Reflow Phenomenon
Key points
Introduction
Predisposing factors
Mechanisms of no reflow
Diagnostic methods
Stages of no-reflow And therapeutic measures
Non pharmacologic therapies
Pharmacologic therapies
Summary
Coronary Physiology Assessment for the Diagnosis and Treatment of Coronary Artery Disease
Key points
Introduction
Importance of ischemia and rationale for percutaneous coronary intervention
Fractional flow reserve
Evidence for fractional flow reserve–guided percutaneous coronary intervention strategy in stable coronary artery disease patients
Fractional flow reserve in acute coronary syndrome patients
Nonhyperemic indices for coronary stenosis assessment
Three-dimensional quantitative coronary angiography and blood flow simulation derived index: quantitative flow ratio
Summary
Bioresorbable Coronary Scaffold Technologies: What’s New?
Key points
Introduction
Overview of magnesium scaffolds
Mechanism of failure
Bioresorbable scaffolds perspectives
Summary
Clinics care points
MicroRNAs and Long Noncoding RNAs in Coronary Artery Disease: New and Potential Therapeutic Targets
Key points
Introduction
MicroRNA-155
MicroRNA-33
MicroRNA-92a
Other microRNAs as a potential therapeutic target
Long noncoding RNAs
Summary
Highlights of the article
Contributors
New Advances in the Treatment of Severe Coronary Artery Calcifications
Key points
Introduction
Calcific lesions phonotypes
Imaging of coronary calcific lesion
New treatment era of coronary calcific lesions
Wire selection
Balloon angioplasty for coronary artery calcifications: not just under pressure
Atherectomy techniques
What’s next to handle?
Refractory Angina—Unsolved Problem
Key points
Epidemiology
Pathophysiology
Pharmacologic treatment
Role of the heart team
Cardiac rehabilitation
Extracorporeal shockwave therapy
Neuromodulation
Coronary sinus reducer
Gene therapy and stem cells
Transmyocardial laser revascularization
Summary
Stent Thrombosis After Percutaneous Coronary Intervention: From Bare-Metal to the Last Generation of Drug-Eluting Stents
Key points
Introduction
Bare-Metal Stent
Durable polymer drug-eluting stent
Bioresorbable polymer drug-eluting stent
Polymer-free drug-eluting stent
Bioresorbable vascular scaffold
Other bioresorbable platforms