Control Theory in Biomedical Engineering

Control Theory in Biomedical Engineering

Applications in Physiology and Medical Robotics

1st Edition - June 29, 2020

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  • Editor: Olfa Boubaker
  • Paperback ISBN: 9780128213506
  • eBook ISBN: 9780128226216

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Control Theory in Biomedical Engineering: Applications in Physiology and Medical Robotics highlights the importance of control theory and feedback control in our lives and explains how this theory is central to future medical developments. Control theory is fundamental for understanding feedback paths in physiological systems (endocrine system, immune system, neurological system) and a concept for building artificial organs. The book is suitable for graduate students and researchers in the control engineering and biomedical engineering fields, and medical students and practitioners seeking to enhance their understanding of physiological processes, medical robotics (legs, hands, knees), and controlling artificial devices (pacemakers, insulin injection devices).Control theory profoundly impacts the everyday lives of a large part of the human population including the disabled and the elderly who use assistive and rehabilitation robots for improving the quality of their lives and increasing their independence.

Key Features

  • Gives an overview of state-of-the-art control theory in physiology, emphasizing the importance of this theory in the medical field through concrete examples, e.g., endocrine, immune, and neurological systems
  • Takes a comprehensive look at advances in medical robotics and rehabilitation devices and presents case studies focusing on their feedback control
  • Presents the significance of control theory in the pervasiveness of medical robots in surgery, exploration, diagnosis, therapy, and rehabilitation


Researchers and graduate students in both control engineering and biomedical engineering fields. Medical students and practitioners who want to enhance their understanding of physiological processes and medical robotics. Professionals in medical industries including those of industry of medical robotics, of artificial devices, of artificial organs and rehabilitation devices

Table of Contents

  • Part I. Applications in Physiology
    1. Modeling and Control in Physiology
    2. Mathematical Modeling of Cholesterol Homeostasis
    3. Adaptive Control of Artificial Pancreas Systems for Treatment of Type 1 Diabetes
    4. Modeling and Optimal Control of Cancer-immune System
    5. Genetic Fuzzy Logic based System for Arrhythmia Classification
    6. Modelling Simple and Complex Handwriting based on EMG Signals

    Part II. Applications in Medical Robotics
    7. Medical Robotics
    8. Wearable Mechatronic Devices for Upper Limb Amputees
    9. Exoskeletons in Upper limb Rehabilitation: A Review to Find key Challenges to Improve Functionality
    10. A Double Pendulum Model for Human Walking Control on the Treadmill and Stride-to-stride Fluctuations: Control of Step Length, Time, Velocity and Position on the Treadmill
    11. Continuum NasoXplorer Manipulator with Shape Memory Actuators for Transnasal Exploration
    12. Tunable Stiffness using Negative Poisson’s Ratio Towards Load-bearing Continuum Tubular Mechanisms in Medical Robotics

Product details

  • No. of pages: 396
  • Language: English
  • Copyright: © Academic Press 2020
  • Published: June 29, 2020
  • Imprint: Academic Press
  • Paperback ISBN: 9780128213506
  • eBook ISBN: 9780128226216

About the Editor

Olfa Boubaker

Olfa Boubaker received her PhD degree in Electrical Engineering from the National Engineering School of Tunis (ENIT) and Habilitation Universitaire degree in Control Engineering from the National Engineering School of Sfax (ENIS), in Tunisia. She is currently a full professor at the National Institute of Applied Science and Technology (INSAT) of University of Carthage where she is actively engaged in teaching and research in control theory, nonlinear systems, and robotics. Professor Boubaker has participated in several research projects in sustainable development areas including the fields of medical robotics, green energy, water preservation, and environment protection. She has supervised 9 theses and 18 Master dissertations and mentored more than 50 engineer graduated projects in the industry. She is an associate editor of the International Journal of Advanced Robotic Systems (SAGE publishing), guest editor for the journals Complexity and Mathematical Problems in Engineering (Hindawi Publishing) and regional editor of the book series Emerging Methodologies and Applications in Modelling, Identification and Control (Elsevier Publishing). She also serves as scientific committee member in several international and peer-reviewed conferences. Professor Boubaker is the principal author of 7 books, editor of 6 special issues, and the author/co-author of more than 150 peer-reviewed papers.

Affiliations and Expertise

National Institute of Applied Science and Technology (INSAT), University of Carthage, Tunisia

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