Control Mechanisms in Developmental Processes - 1st Edition - ISBN: 9780123955524, 9780323156288

Control Mechanisms in Developmental Processes

1st Edition

Editors: Michael Locke
eBook ISBN: 9780323156288
Imprint: Academic Press
Published Date: 1st January 1967
Page Count: 316
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Control Mechanisms in Developmental Processes covers the proceedings of the 1967 26th Symposium of The Society for Developmental Biology, held in La Jolla, California. This book is divided into three parts encompassing 10 chapters that summarize the role of cytoplasmic units and the nucleus in developmental processes and the regulatory mechanisms.
The opening part of the book describes the chemical changes during the development of plastids in leaves of higher plants. The book goes on discussing the nuclear and cytoplasmic controls in Neurospora morphology. This compilation also examines the aspects of development, growth, and control in the basal bodies and flagella of Chlamydomonas reinhardii. The second part describes genetic systems in plants that serve to initiate or program the sequence in plant development and the life cycle of hybrids between somatic cells of different species. A chapter discusses the genetic basis of higher plant morphogenesis by analysis of the differences between genotypes that differ from each other with respect to a single gene having a pronounced and highly specific effect upon form. A discussion on the activation of protein synthesis upon fertilization and early development of animal eggs to the biochemical basis of the determination process is also included. The concluding part deals with the differentiation of erythroid cells; the induction of hemoglobin synthesis; the regulation of heme and globin synthesis; and the role of heme in the synthesis and assembly of hemoglobin. This part also describes the differentiation of cells to the point where they can perform the various types of immunological reactions.
This book is an invaluable source for developmental biologists and researchers.

Table of Contents

Contributors and Presiding Chairmen


History of the Symposium Volumes

I. The Role of Cytoplasmic Units

Control Mechanisms in Plastid Development


The Control of Plastid Development by the Nuclear Genome

Proplastid to Chloroplast

Summary Discussion

Chairman's Comments—June Lascelles


Nuclear and Cytoplasmic Control of Morphology in Neurospora

Comparison of Biochemical and Morphological Mutants

Nuclear Control of Morphology

Extranuclear Control of Morphology

Involvement of Mitochondria

Possible Involvement of Mitochondrial DNA

Cytology of Abnormal Cultures

Biology of Conversion

Cytochrome Pattern in Conversion



Developmental and Control Processes in the Basal Bodies and Flagella of Chlamydomonas reinhardii


The Development and Regression of Flagella and Basal Bodies in Chlamydomonas reinhardii

The Genetic Control of Flagella Structure in Chlamydomonas reinhardii

Macromolecular Basis of Morphopoiesis and Structure in Flagella

Regeneration of Chlamydomonas Flagella: Some Experimental and Theoretical Considerations

General Discussion


II. The Role of the Nucleus

Genetic Systems Regulating Gene Expression during Development


Illustrations of the Mode of Operation of a Regulatory System in Maize

Evidence of Controlling Elements in Organisms Other Than Maize


Gene Action, Mitotic Frequency, and Morphogenesis in Higher Plants


Relationships between Cell Enlargements and Cell Division

Effects of Genes Acting at Different Stages of Development

Developmental Features of Corngrass in Maize

The Hooded Gene in Barley

Relationship between Mitotic Frequency and Orientation of Mitoses

Discussion and Summary


Regulation of the Cell Cycle in Mammalian Cells: Inferences and Speculations Based on Observations of Interspecific Somatic Hybrids

Prefatory Note


Properties of Rat ×Mouse and Hamster ×Mouse Hybrids

Inferences concerning the Coordination of the Events of the Cell Cycle

Appendix I: Summary of Work on Hybridization of Somatic Cells

Appendix II: Notes


Masked Messenger RNA and Cytoplasmic DNA in Relation to Protein Synthesis and Processes of Fertilization and Determination in Embryonic Development


Messenger RNA

Stimulation of Protein Synthesis upon Fertilization

Evidence for Masked Messenger RNA (mmRNA)

Extent and Duration of Action of mmRNA

mmRNA Synthesis during Early Development

Polysome Formation upon Fertilization

Protein Synthesis in Unfertilized Eggs

Location of mmRNA in Unfertilized Eggs and in Developing Embryos

Relation of Histones to mRNA Synthesis

mmRNA Synthesis and Embryonic Determination

Cytoplasmic DNA


Chairman's Comments—Arthur Η. Whiteley


III. Regulatory Mechanisms

Erythroid Cell Differentiation and the Synthesis and Assembly of Hemoglobin


Erythroid Cell Differentiation and the Induction of Hemoglobin Synthesis

Regulation of Heme Biosynthesis

Regulation of Globin Synthesis by Heme

The Role of Heme in the Assembly of Hemoglobin


The Development of Immunocompetent Cells


Tissue Interaction during Lymphoid Morphogenesis

The Thymus as a Source of Immunocompetent Cells

Bone Marrow as a Source of Immunocompetent Cells

Embryonic Liver as a Source of Immunocompetent Cells

Yolk Sac Origin of Immunocompetent Cells

Concluding Remarks



Regulatory Action of Estrogenic Hormones


The Effect of Estrogen on RNA Synthesis

The Effect of Metabolic Inhibitors

The Biological Activity of Uterine RNA

Morphological Effects

Enzymatic Effects

Physiological Effects

Estrogen Binding and RNA Synthesis


Author Index

Subject Index


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© Academic Press 1967
Academic Press
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About the Editor

Michael Locke

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