Contemporary Challenges in Sudden Cardiac Death, An Issue of Cardiac Electrophysiology Clinics

1st Edition, Volume 9-4 - November 30, 2017
Authors: Mohammad Shenasa, N.A. Mark Estes III, Gordon F. Tomaselli
Language: English
Hardback ISBN:
9 7 8 - 0 - 3 2 3 - 5 5 2 6 8 - 4
eBook ISBN:
9 7 8 - 0 - 3 2 3 - 5 5 2 6 9 - 1

This issue of Cardiac Electrophysiology Clinics, edited by Drs. Mohammad Shenasa, N. A. Mark Estes III, and Gordon F. Tomaselli, will cover Contemporary Challenges in Sudden… Read more

Contemporary Challenges in Sudden Cardiac Death, An Issue of Cardiac Electrophysiology Clinics

Purchase options

Info / Buy

LIMITED OFFER

Save 50% on book bundles

Immediately download your ebook while waiting for your print delivery. No promo code is needed.

Institutional subscription on ScienceDirect

Request a sales quote

This issue of Cardiac Electrophysiology Clinics, edited by Drs. Mohammad Shenasa, N. A. Mark Estes III, and Gordon F. Tomaselli, will cover Contemporary Challenges in Sudden Cardiac Death. Topics covered in this issue include Pathophysiology; Basic electrophysiological mechanism; Channelopathy and Myopathy as causes of sudden cardiac death; Public access to defibrillation; Sudden cardiac death in children adolescence; Sudden cardiac death in specific cardiomyopathies; Ventricular arrhythmias and sudden cardiac death; lessons learned from cardiac implantable rhythm devices; future directions, and more.

Cover image
Title page
Table of Contents
Copyright
Contributors
Forthcoming Issues
Foreword
Preface
Sudden Cardiac Death: Interface Between Pathophysiology and Epidemiology
Key points
Incidence of sudden cardiac arrest
Causes and mechanisms of cardiac arrest
Mechanistic targets derived from epidemiologic subdivisions
Mechanisms and pathophysiology of sudden cardiac arrest in coronary heart disease
Transition from myocardial instability to lethal tachyarrhythmias
Asystolic arrest
Pulseless electrical activity
Basic Electrophysiologic Mechanisms of Sudden Cardiac Death Caused by Acute Myocardial Ischemia and Infarction
Key points
Introduction
The acute phase of myocardial ischemia and infarction
Channelopathies as Causes of Sudden Cardiac Death
Key points
Long QT syndrome
Catecholaminergic polymorphic ventricular tachycardia
Brugada syndrome
Public Access Defibrillation: Is This Making Any Difference? Controversial Issues in Resuscitation from Cardiac Arrest
Key points
Introduction
Launching of bystander use of automatic defibrillators: public access defibrillation
Equipping of police vehicles and training of police in the use of automated external defibrillators
Community-based studies of use and outcome
Concentration of shockable cardiac arrests in public locations
Contemporary use of automated external defibrillators in cardiac arrests witnessed in public locations
Opportunities for further improvement in use of automated external defibrillators in all cardiac arrests occurring in public locations
Circulatory phase of cardiac resuscitation in relation to shock and use of automated external defibrillators
Controversial and noncontroversial aspects of cardiopulmonary resuscitation
Summary
Sudden Cardiac Death During Sports Activities in the General Population
Key points
Sports activity: conclusively beneficial for long-term sudden cardiac death risk
Sudden death in the young competitive athlete: the apparent part of the iceberg
Sudden cardiac death among recreational sports participants: the majority of sports-related sudden cardiac death
Sports-related sudden cardiac death presents with highly homogenous characteristics
How to tackle sports-related sudden cardiac death?
Summary
Sudden Cardiac Death in Children and Adolescents
Key points
Introduction
Epidemiology
Etiologies
Autopsy findings
Genetic testing
Cascade screening
Community screening
Special populations
Treatment
Summary
Sudden Cardiac Death in Genetic Cardiomyopathies
Key points
Dilated cardiomyopathy
Hypertrophic cardiomyopathy
Arrhythmogenic right ventricular cardiomyopathy
Electrocardiographic Markers of Sudden Cardiac Death (Including Left Ventricular Hypertrophy)
Key points
Main causes of sudden cardiac death
Electrocardiographic markers of sudden cardiac death: role of the electrocardiogram as a part of a risk stratification of sudden cardiac death
Risk prediction of ventricular arrhythmias after myocardial infarction
Electrocardiographic markers of sudden cardiac death: depolarization abnormalities
Presence of ventricular late potentials using high-resolution or signal-averaged electrocardiography
Summary
Prediction and Prevention of Sudden Cardiac Death
Key points
Introduction
Ischemic heart disease
Nonischemic cardiomyopathy
Risk stratification of sudden cardiac death in inherited channelopathies
Sudden cardiac death in the athlete
Summary
Role of Cardiac Imaging in Evaluating Risk for Sudden Cardiac Death
Key points
Introduction
Concepts in risk stratification
Cardiac imaging and sudden cardiac death pathophysiology
Evaluation of arrhythmic substrates
Myocardial sympathetic denervation and the risk of sudden cardiac death
Summary
Biomarkers to Predict Cardiovascular Death
Key points
Biomarkers of cardiovascular death in the general population
Biomarkers of cardiovascular death in coronary artery disease
Biomarkers of sudden cardiac death in heart failure
Future directions
Summary
Cardiac Innervation and the Autonomic Nervous System in Sudden Cardiac Death
Key points
Introduction
Anatomy
Autonomic nervous system and cardiac pathophysiology
Neural remodeling in the setting of myocardial infarction
Neuraxial modulation to reduce risk of sudden cardiac death
Summary
Sudden Cardiac Death in Ischemic Heart Disease: Pathophysiology and Risk Stratification
Key points
Introduction
Pathophysiology of sudden cardiac death in ischemic heart disease
Remodeling after myocardial infarction and sudden cardiac death
Current risk stratification of sudden cardiac death in ischemic heart disease
Surrogate measures of conduction disorders
Imaging and quantification of myocardial scar
Surrogate measures of dispersion of repolarization
Surrogate measures of autonomic function
Imaging of cardiac sympathetic innervation
Ambulatory monitoring
Electrophysiologic study
Biomarkers
Genomics
Noninvasive clinical risk variables
Summary
Ventricular Arrhythmias and Sudden Cardiac Death
Key points
Introduction
Ischemic cardiomyopathy
Nonischemic cardiomyopathy
Hypertrophic cardiomyopathy
Arrhythmogenic right ventricular cardiomyopathy
Repaired congenital heart disease
Brugada syndrome
Long QT syndrome
Short QT syndrome
Catecholaminergic polymorphic ventricular tachycardia
Early repolarization patterns
Idiopathic ventricular tachycardia
Future directions
Summary
Heart Failure and Sudden Cardiac Death
Key points
Introduction
Risk stratification: beyond the left ventricular ejection fraction
MRI: delayed enhancement: metaiodobenzylguanidine
Medical therapies for reduction of mortality in patients with heart failure
Device and ablative strategies for reduction of mortality in patients with heart failure
Wearable cardioverter defibrillator
Antiarrhythmic drugs and ablation for ventricular tachycardia in heart patients with failure
Nonischemic cardiomyopathies
End-of-life care
Sudden Cardiac Death in Acute Coronary Syndromes
Key points
Introduction
Sudden cardiac arrest as initial manifestation of an acute coronary syndrome
In-hospital complex ventricular arrhythmias
Prognostic significance of in-hospital complex ventricular arrhythmias
Acute treatment of ventricular tachyarrhythmias in the setting of acute coronary syndromes
Other measures for management of ventricular tachyarrhythmias in patients with acute coronary syndromes
Catheter ablation in the acute setting
Implantable cardioverter-defibrillator
Summary
Neuromuscular Disease: Cardiac Manifestations and Sudden Death Risk
Key points
Introduction and general principles
Muscular dystrophies, cardiac arrhythmias, and sudden cardiac death
Summary/future directions
Sudden Cardiac Death: Lessons Learned from Cardiac Implantable Rhythm Devices
Key points
Introduction
Establishment of implantable cardioverter–defibrillator devices
The negative lessons
Summary
Primary Prevention Implantable Cardiac Defibrillator Trials: What Have We Learned?
Key points
Introduction
Primary prevention implantable cardioverter-defibrillators in ischemic cardiomyopathy, 1990s
Primary prevention implantable cardioverter-defibrillators in ischemic cardiomyopathy, 2000s
Primary prevention implantable cardioverter-defibrillators in nonischemic cardiomyopathy
Evidence that benefit from implantable cardioverter-defibrillators is not uniformly distributed in tested populations
Summary
The Subcutaneous Defibrillator
Key points
Introduction
The subcutaneous defibrillator
Subcutaneous implantable cardioverter-defibrillator efficacy
Procedural complications
Inappropriate shocks
Subcutaneous implantable cardioverter-defibrillator limitations
Comparison with transvenous implantable cardioverter-defibrillator
Summary
Future Directions: Management of Sudden Cardiac Death
Key points
Introduction
National cardiac arrest registry
Fostering a culture of action
Optimizing emergency medical service system capabilities and performance
Optimizing hospital performance
Accelerating research
Structured collaboration
Summary

Purchase options

Save 50% on book bundles

Institutional subscription on ScienceDirect

Mohammad Shenasa

N.A. Mark Estes III

Gordon F. Tomaselli